{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T18:52:02Z","timestamp":1781463122260,"version":"3.54.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T00:00:00Z","timestamp":1632182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Methaqualone, known previously under the brand name Quaalude, is a Schedule I sedative hypnotic drug that may cause neurotoxicity in overdose, characterized by somnolence, hyperreflexia and muscular hyperactivity. We present a case of a 21-year-old male who reportedly ingested methaqualone in addition to insufflation of street cocaine. He subsequently developed hypoxia, hyperreflexia, myoclonus and altered mental status. His laboratory results were notable for the presence of methemoglobinemia, which was most likely due to a cocaine contaminant. Laboratory analysis of the alleged methaqualone pills identified the substance as SL-164, a dichlorinated methaqualone analog. Urine toxicology results were positive for SL-164 (and presumed metabolites) as well as for cocaine and tetrahydrocannabinol metabolites. The patient was treated with supplemental oxygen and a benzodiazepine (lorazepam) and observed in the Emergency Department until his symptoms resolved. This case highlights current community access to methaqualone analogs. The case also focuses on laboratory techniques used to identify the methaqualone analog.<\/jats:p>","DOI":"10.1093\/jat\/bkab103","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T03:11:10Z","timestamp":1632193870000},"page":"e82-e87","source":"Crossref","is-referenced-by-count":9,"title":["Qua-alluding to the Past: A Case of Methaqualone Analog Ingestion"],"prefix":"10.1093","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1944-3288","authenticated-orcid":false,"given":"Kyle","family":"Lund","sequence":"first","affiliation":[{"name":"Department of Pathology, Center for Advanced Laboratory Medicine, UC San Diego Health, 10300 Campus Point Dr. Suite 150, San Diego, CA 92121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Srihari","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Keck School of Medicine of USC, 1200 N. State Street Room 1060R, Los Angeles, CA 90033, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond T","family":"Suhandynata","sequence":"additional","affiliation":[{"name":"Department of Pathology, Center for Advanced Laboratory Medicine, UC San Diego Health, 10300 Campus Point Dr. Suite 150, San Diego, CA 92121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristy","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Emergency Medicine, UC San Diego Health, 200 W. Arbor Dr. #8676, San Diego, CA 92103, USA"},{"name":"Department of Emergency Medicine, UC San Diego Health, 200 W. Arbor Dr. #8676, San Diego, CA 92103, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"Department of Pathology, Center for Advanced Laboratory Medicine, UC San Diego Health, 10300 Campus Point Dr. Suite 150, San Diego, CA 92121, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allyson A","family":"Kreshak","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Division of Medical Toxicology, UC San Diego Health, 200 W. 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