{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T08:41:06Z","timestamp":1790066466317,"version":"4.0.1"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T00:00:00Z","timestamp":1648857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>5-MeO-DALT or 5-methoxy-N,N-diallyltryptamine is a derivative of tryptamines, consumed for its hallucinogenic and entheogenic effects. We report the case of a 46-year-old-man, presenting with a brief loss of consciousness and visual hallucinations, after the consumption of three 5-MeO-DALT tablets bought online. Liquid chromatography coupled to tandem mass spectrometry method was performed, and 5-MeO-DALT was quantified in both the tablets (32.5\u2009mg per tablet, 11% of purity) and the patient\u2019s plasma (7\u2009ng\/mL\u20148\u2009h between the consumption and the blood sample). 5-MeO-DALT poisonings are rarely described. Given the broad availability of these products, it is important that emergency department physicians and clinical toxicologists do not overlook the possibility of the ingestion of recreational tryptamines, especially since they are not detected by most routine toxicological screening.<\/jats:p>","DOI":"10.1093\/jat\/bkac021","type":"journal-article","created":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T03:01:48Z","timestamp":1648868508000},"page":"e186-e190","source":"Crossref","is-referenced-by-count":4,"title":["Loss of Consciousness and Visual Hallucinations Related to 5-MeO-DALT Intake, a Case Report Confirmed by Toxicological Analyses"],"prefix":"10.1093","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6594-5855","authenticated-orcid":false,"given":"Laur\u00e8ne","family":"Dufayet","sequence":"first","affiliation":[{"name":"Centre Antipoison de Paris\u2014F\u00e9d\u00e9ration de Toxicologie (FeTox), H\u00f4pital Fernand-Widal, APHP , 200 Rue du Faubourg Saint-Denis, Paris 75010, France"},{"name":"INSERM, UMRS-1144, Facult\u00e9 de Pharmacie, Universit\u00e9 Paris Cit\u00e9, 4 Avenue de L\u2019observatoire , Paris 75006, France"},{"name":"Unit\u00e9 M\u00e9dico-judiciaire, H\u00f4tel-Dieu, APHP , 1 Place du Parvis Notre Dame, Paris 75004, France"},{"name":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 de Paris Cit\u00e9, 15 Rue de L\u2019\u00e9cole de M\u00e9decine , Paris 75006, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Langrand","sequence":"additional","affiliation":[{"name":"Centre Antipoison de Paris\u2014F\u00e9d\u00e9ration de Toxicologie (FeTox), H\u00f4pital Fernand-Widal, APHP , 200 Rue du Faubourg Saint-Denis, Paris 75010, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Laboratoire de Pharmacologie-Toxicologie, Centre Hospitalier Universitaire Raymond Poincar\u00e9, APHP , 104 Bd Raymond Poincar\u00e9, Garches 92380, France"},{"name":"Plateforme de Spectrometrie de Masse (MasSpecLab) INSERM UMR 1173, UFR des Sciences de la Sante Simone Veil, Universit\u00e9 Versailles Saint-Quentin-En-Yvelines (UVSQ-Paris Saclay) , Montigny le Bretonneux 78180, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amine","family":"Islam Larabi","sequence":"additional","affiliation":[{"name":"Laboratoire de Pharmacologie-Toxicologie, Centre Hospitalier Universitaire Raymond Poincar\u00e9, APHP , 104 Bd Raymond Poincar\u00e9, Garches 92380, France"},{"name":"Plateforme de Spectrometrie de Masse (MasSpecLab) INSERM UMR 1173, UFR des Sciences de la Sante Simone Veil, Universit\u00e9 Versailles Saint-Quentin-En-Yvelines (UVSQ-Paris Saclay) , Montigny le Bretonneux 78180, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,4,2]]},"reference":[{"key":"2022081310470785100_R1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.2174\/1570159X13666141210222409","article-title":"Recreational use, analysis and toxicity of tryptamines","volume":"13","author":"Tittarelli","year":"2015","journal-title":"Current Neuropharmacology"},{"key":"2022081310470785100_R2","author":"PubChem"},{"key":"2022081310470785100_R3","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s00204-015-1513-x","article-title":"The hallucinogenic world of tryptamines: an updated review","volume":"89","author":"Ara\u00fajo","year":"2015","journal-title":"Archives of Toxicology"},{"key":"2022081310470785100_R4","article-title":"The Last Interview With Alexander Shulgin","author":"Hamilton","year":"2010"},{"key":"2022081310470785100_R5","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.pnpbp.2012.05.022","article-title":"The recreational tryptamine 5-MeO-DALT (N,N-diallyl-5-methoxytryptamine): a brief review","volume":"39","author":"Corkery","year":"2012","journal-title":"Progress in Neuro-psychopharmacology & Biological Psychiatry"},{"key":"2022081310470785100_R6","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2019.06.011","article-title":"Prevalence of New Psychoactive Substances (NPS) and conventional drugs of abuse (DOA) in high risk populations from Paris (France) and its suburbs","volume":"204","author":"Larabi","year":"2019","journal-title":"Drug and Alcohol Dependence"},{"key":"2022081310470785100_R7","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1373\/clinchem.2018.299727","article-title":"Effect of smoked cannabis on vigilance and accident risk using simulated driving in occasional and chronic users and the pharmacokinetic\u2013pharmacodynamic relationship","volume":"65","author":"Hartley","year":"2019","journal-title":"Clinical Chemistry"},{"key":"2022081310470785100_R8","doi-asserted-by":"crossref","DOI":"10.1016\/j.toxac.2015.03.063","article-title":"Analyses de poudres : int\u00e9r\u00eat du dosage des produits de coupage","volume":"27","author":"Mayer","year":"2015","journal-title":"Toxicologie Analytique Et Clinique"},{"key":"2022081310470785100_R9","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/dta.2936","article-title":"Hair analysis can support the follow-up addiction care after acute New Psychoactive Substances intoxication: illustration by two cases","volume":"13","author":"Lagoutte-Renosi","year":"2021","journal-title":"Drug Testing and Analysis"},{"key":"2022081310470785100_R10","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.toxac.2015.03.019","article-title":"Apport d\u2019une strat\u00e9gie analytique combinant des approches in vitro, in silico et in vivo dans un cas de polyintoxication impliquant deux nouvelles drogues de synth\u00e8se","volume":"27","author":"Phanithavong","year":"2015","journal-title":"Toxicologie Analytique Et Clinique"},{"key":"2022081310470785100_R11","doi-asserted-by":"crossref","DOI":"10.1016\/j.toxac.2015.03.025","article-title":"M\u00e9thiopropamine, m\u00e9thoxph\u00e9nidine, diph\u00e9nidine, D2PM, 5-MeO-DALT: \u00e0 propos de nouveaux cas d\u2019exposition unique ou en polyconsommation","volume":"27","author":"Ferec","year":"2015","journal-title":"Toxicologie Analytique Et Clinique"},{"key":"2022081310470785100_R12","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/1556-4029.12367","article-title":"Delirium due to intoxication from the novel synthetic tryptamine 5-MeO-DALT","volume":"59","author":"Jovel","year":"2014","journal-title":"Journal of Forensic Sciences"},{"key":"2022081310470785100_R13","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1111\/aas.12765","article-title":"5-MeO-DALT; a novel designer drug on the market causing acute delirium and rhabdomyolysis","volume":"60","author":"Kalasho","year":"2016","journal-title":"Acta Anaesthesiologica Scandinavica"},{"key":"2022081310470785100_R14","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1016\/j.bmcl.2013.03.066","article-title":"An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging \u2018Novel Psychoactive Drugs\u2019","volume":"23","author":"Arunotayanun","year":"2013","journal-title":"Bioorganic & Medicinal Chemistry Letters"},{"key":"2022081310470785100_R15","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.neuropharm.2018.02.028","article-title":"Receptor binding profiles and behavioral pharmacology of ring-substituted N,N-diallyltryptamine analogs","volume":"142","author":"Klein","year":"2018","journal-title":"Neuropharmacology"},{"key":"2022081310470785100_R16","doi-asserted-by":"crossref","first-page":"7831","DOI":"10.1007\/s00216-015-8955-0","article-title":"Metabolism of the new psychoactive substances N,N-diallyltryptamine (DALT) and 5-methoxy-DALT and their detectability in urine by GC-MS, LC-MSn, and LC-HR-MS-MS","volume":"407","author":"Michely","year":"2015","journal-title":"Analytical and Bioanalytical Chemistry"},{"key":"2022081310470785100_R17","article-title":"Critical Review Report: 5-MeO-DALT","author":"World Health Organization","year":"2020"}],"container-title":["Journal of Analytical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jat\/advance-article-pdf\/doi\/10.1093\/jat\/bkac021\/43469223\/bkac021.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jat\/article-pdf\/46\/7\/e186\/45413997\/bkac021.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jat\/article-pdf\/46\/7\/e186\/45413997\/bkac021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T10:47:50Z","timestamp":1660387670000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jat\/article\/46\/7\/e186\/6562548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,2]]},"references-count":17,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,4,2]]},"published-print":{"date-parts":[[2022,8,13]]}},"URL":"https:\/\/doi.org\/10.1093\/jat\/bkac021","relation":{},"ISSN":["0146-4760","1945-2403"],"issn-type":[{"value":"0146-4760","type":"print"},{"value":"1945-2403","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,9,1]]},"published":{"date-parts":[[2022,4,2]]}}}