{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:15:59Z","timestamp":1778876159214,"version":"3.51.4"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The intentional ingestion of sodium nitrite causes toxicity by inducing methemoglobinemia, which can lead to cyanosis, hypotension and death. The number of reported suicide cases has significantly increased in the past 10 years as sodium nitrite is readily available online. The traditional tests for nitrite and nitrate require specialized detection methods which are not typically available in a postmortem toxicology laboratory. This rise in sodium nitrite overdose cases indicates the need for a simple, quick test for suspected nitrite toxicity. In this study, a common Griess reagent color test (MQuant\u2122 Nitrite Test Strips) was used as a presumptive method in cases where the ingestion of sodium nitrite was suspected. The test results were consistent between specimens in all cases, and vitreous humor was identified as a reliable matrix to be used in the cases of suspected sodium nitrite poisonings. Case reports of five patients who died of suicide by sodium nitrite in a 6-month span are presented.<\/jats:p>","DOI":"10.1093\/jat\/bkad038","type":"journal-article","created":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T12:25:04Z","timestamp":1687004704000},"page":"746-749","source":"Crossref","is-referenced-by-count":11,"title":["Presumptive identification of\u00a0nitrite by Griess reagent test strips\u2014Case reports of\u00a0fatal poisoning with sodium nitrite"],"prefix":"10.1093","volume":"47","author":[{"given":"Man","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine , 4800 S.W. 35th Drive, Gainesville, FL 32610, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3747-5379","authenticated-orcid":false,"given":"Michael T","family":"Truver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L","family":"Hoyer","sequence":"additional","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine , 4800 S.W. 35th Drive, Gainesville, FL 32610, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris W","family":"Chronister","sequence":"additional","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine , 4800 S.W. 35th Drive, Gainesville, FL 32610, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5799-1787","authenticated-orcid":false,"given":"Bruce A","family":"Goldberger","sequence":"additional","affiliation":[{"name":"Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine , 4800 S.W. 35th Drive, Gainesville, FL 32610, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,6,17]]},"reference":[{"key":"2023110617123186500_R1","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1056\/NEJMc1712813","article-title":"Methemoglobinemia due to antifreeze ingestion","volume":"377","author":"Farkas","year":"2017","journal-title":"New England Journal of Medicine"},{"key":"2023110617123186500_R2","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3109\/15563659409000447","article-title":"Methemoglobinemia caused by the accidental contamination of\u00a0drinking water with sodium nitrite","volume":"32","author":"Bradberry","year":"1994","journal-title":"Journal of Toxicology. 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