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As part of a routine procedure, Psychemedics frequently encounters questions from clients\/Medical Review Officers regarding opioid hair concentrations in relation to the amount of opioids taken as part of a prescription. In this article, we have analyzed a large number of real-world examples of opioid hair concentrations following self-reported consumption of an opioid prescription regimen. This dataset provides a reference point of opioid hair concentrations after an extensive aqueous wash that likely corresponds to consumption of an opioid prescription regimen. Practitioners in the field could use this reference to make decisions on the opioid concentration of a hair sample in relation to a client-provided prescription.<\/jats:p>","DOI":"10.1093\/jat\/bkae101","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T17:29:36Z","timestamp":1735838976000},"page":"201-207","source":"Crossref","is-referenced-by-count":2,"title":["Opioid hair concentrations using retrospective prescription data from a United States workplace testing population"],"prefix":"10.1093","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2076-4505","authenticated-orcid":false,"given":"G Neil","family":"Stowe","sequence":"first","affiliation":[{"name":"Psychemedics Corporation , 5832 Uplander Way, Culver City, CA 90230,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7331-2871","authenticated-orcid":false,"given":"Ryan B","family":"Paulsen","sequence":"additional","affiliation":[{"name":"Psychemedics Corporation , 5832 Uplander Way, Culver City, CA 90230,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael I","family":"Schaffer","sequence":"additional","affiliation":[{"name":"Non-Affiliated , 5832 Uplander Way, Culver City, CA 90230,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,1,2]]},"reference":[{"key":"2025031016571181700_R1","doi-asserted-by":"publisher","first-page":"4358","DOI":"10.1021\/ac049555t","article-title":"Simultaneous quantification of opiates, cocaine and metabolites in hair by LC-APCI-MS\/MS","volume":"76","author":"Scheidweiler","year":"2004","journal-title":"Anal Chem"},{"key":"2025031016571181700_R2","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1093\/jat\/23.6.396","article-title":"Drug testing with alternative matrices II. 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