{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:21:46Z","timestamp":1792099306859,"version":"4.4.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T00:00:00Z","timestamp":1542758400000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5,1]]},"DOI":"10.1093\/jat\/bky092","type":"journal-article","created":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T04:46:29Z","timestamp":1540356389000},"page":"316-320","source":"Crossref","is-referenced-by-count":24,"title":["A Liquid-Chromatography High-Resolution Mass Spectrometry Method for Non-FDA Approved Benzodiazepines"],"prefix":"10.1093","volume":"43","author":[{"given":"Xander M R","family":"van Wijk","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, University of California, San Francisco and Zuckerberg San Francisco General, 1001 Potrero Ave, ZSFG Bldg 5, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra","family":"Yun","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of California, San Francisco and Zuckerberg San Francisco General, 1001 Potrero Ave, ZSFG Bldg 5, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin","family":"Hooshfar","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of California, San Francisco and Zuckerberg San Francisco General, 1001 Potrero Ave, ZSFG Bldg 5, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann M","family":"Arens","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Hennepin Healthcare, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derrick","family":"Lung","sequence":"additional","affiliation":[{"name":"California Poison Control System, San Francisco Division, CA, USA"},{"name":"Emergency Medicine, San Mateo Medical Center, San Mateo, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan H B","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of California, San Francisco and Zuckerberg San Francisco General, 1001 Potrero Ave, ZSFG Bldg 5, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara L","family":"Lynch","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of California, San Francisco and Zuckerberg San Francisco General, 1001 Potrero Ave, ZSFG Bldg 5, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,11,14]]},"reference":[{"key":"2019041204484768000_bky092C1","doi-asserted-by":"crossref","first-page":"686","DOI":"10.2105\/AJPH.2016.303061","article-title":"Increasing benzodiazepine prescriptions and overdose mortality in the United States, 1996\u20132013","volume":"106","author":"Bachhuber","year":"2016","journal-title":"American Journal of Public Health"},{"key":"2019041204484768000_bky092C2","author":"U.S. Department of Justice, Drug Enforcement Administration and Office of Diversion Control","year":"2016"},{"key":"2019041204484768000_bky092C3","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1001\/jamainternmed.2016.4306","article-title":"Adverse effects from counterfeit alprazolam tablets","volume":"176","author":"Arens","year":"2016","journal-title":"JAMA Internal Medicine"},{"key":"2019041204484768000_bky092C4","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1080\/15563650.2016.1240806","article-title":"Synthetic agents off the darknet: a case of U-47700 and phenazepam abuse","volume":"55","author":"Vo","year":"2017","journal-title":"Clinical Toxicology (Philadelphia, Pa.)"},{"key":"2019041204484768000_bky092C5","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/dta.2211","article-title":"The emergence of new psychoactive substance (NPS) benzodiazepines: a review","volume":"10","author":"Manchester","year":"2018","journal-title":"Drug Testing and Analysis"},{"key":"2019041204484768000_bky092C6","author":"Mignone","year":"2017"},{"key":"2019041204484768000_bky092C7","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1002\/dta.2003","article-title":"Detectability of designer benzodiazepines in CEDIA, EMIT II Plus, HEIA, and KIMS II immunochemical screening assays","volume":"9","author":"Pettersson Bergstrand","year":"2017","journal-title":"Drug Testing and Analysis"},{"key":"2019041204484768000_bky092C8","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jchromb.2016.08.047","article-title":"Development and application of a multi-component LC-MS\/MS method for determination of designer benzodiazepines in urine","volume":"1035","author":"Pettersson Bergstrand","year":"2016","journal-title":"Journal of Chromatography. B: Analytical Technologies in the Biomedical and Life Sciences"},{"key":"2019041204484768000_bky092C9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1373\/clinchem.2015.241315","article-title":"Comparison of information-dependent acquisition on a tandem quadrupole TOF vs a triple quadrupole linear ion trap mass spectrometer for broad-spectrum drug screening","volume":"62","author":"Thoren","year":"2016","journal-title":"Clinical Chemistry"},{"key":"2019041204484768000_bky092C10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jat\/bkw112","article-title":"Optimization and validation of high-resolution mass spectrometry data analysis parameters","volume":"41","author":"Colby","year":"2017","journal-title":"Journal of Analytical Toxicology"},{"key":"2019041204484768000_bky092C11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.forsciint.2016.09.006","article-title":"Blood concentrations of new designer benzodiazepines in forensic cases","volume":"268","author":"Hoiseth","year":"2016","journal-title":"Forensic Science International"},{"key":"2019041204484768000_bky092C12","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1002\/jms.3279","article-title":"Detection and identification of the designer benzodiazepine flubromazepam and preliminary data on its metabolism and pharmacokinetics","volume":"48","author":"Moosmann","year":"2013","journal-title":"Journal of Mass Spectrometry"},{"key":"2019041204484768000_bky092C13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF00280074","article-title":"Single and multiple dose pharmacokinetics of etizolam in healthy subjects","volume":"40","author":"Fracasso","year":"1991","journal-title":"European Journal of Clinical Pharmacology"},{"key":"2019041204484768000_bky092C14","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.forsciint.2008.08.012","article-title":"Case report: Etizolam and its major metabolites in two unnatural death cases","volume":"182","author":"Nakamae","year":"2008","journal-title":"Forensic Science International"},{"key":"2019041204484768000_bky092C15","doi-asserted-by":"crossref","DOI":"10.1093\/jat\/bkx107","article-title":"Suspect screening using LC-QqTOF is a useful tool for detecting drugs in biological samples","author":"Colby","year":"2018","journal-title":"Journal of Analytical Toxicology"}],"container-title":["Journal of Analytical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jat\/article-pdf\/43\/4\/316\/28359177\/bky092.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,4]],"date-time":"2022-09-04T14:33:59Z","timestamp":1662302039000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jat\/article\/43\/4\/316\/5194291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,14]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,11,14]]},"published-print":{"date-parts":[[2019,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jat\/bky092","relation":{},"ISSN":["0146-4760","1945-2403"],"issn-type":[{"value":"0146-4760","type":"print"},{"value":"1945-2403","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,5]]},"published":{"date-parts":[[2018,11,14]]}}}