{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T01:03:19Z","timestamp":1793494999498,"version":"4.5.0"},"reference-count":201,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>With advances in analytical technology and new research informing result interpretation, oral fluid (OF) testing has gained acceptance over the past decades as an alternative biological matrix for detecting drugs in forensic and clinical settings. OF testing offers simple, rapid, non-invasive, observed specimen collection. This article offers a review of the scientific literature covering analytical methods and interpretation published over the past two decades for amphetamines, cannabis, cocaine, opioids, and benzodiazepines. Several analytical methods have been published for individual drug classes and, increasingly, for multiple drug classes. The method of OF collection can have a significant impact on the resultant drug concentration. Drug concentrations for amphetamines, cannabis, cocaine, opioids, and benzodiazepines are reviewed in the context of the dosing condition and the collection method. Time of last detection is evaluated against several agencies' cutoffs, including the proposed Substance Abuse and Mental Health Services Administration, European Workplace Drug Testing Society and Driving Under the Influence of Drugs, Alcohol and Medicines cutoffs. A significant correlation was frequently observed between matrices (i.e., between OF and plasma or blood concentrations); however, high intra-subject and inter-subject variability precludes prediction of blood concentrations from OF concentrations. This article will assist individuals in understanding the relative merits and limitations of various methods of OF collection, analysis and interpretation.<\/jats:p>","DOI":"10.1093\/jat\/bkz048","type":"journal-article","created":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T15:10:50Z","timestamp":1559661050000},"page":"415-443","source":"Crossref","is-referenced-by-count":115,"title":["Oral Fluid Drug Testing: Analytical Approaches, Issues and Interpretation of Results"],"prefix":"10.1093","volume":"43","author":[{"given":"Nathalie A","family":"Desrosiers","sequence":"first","affiliation":[{"name":"Centre of Forensic Sciences, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn A","family":"Huestis","sequence":"additional","affiliation":[{"name":"Lambert Center for the Study of Medicinal Cannabis and Hemp, Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,7,2]]},"reference":[{"key":"2019101604085239400_ref1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1034\/j.1601-0825.2002.02851.x","article-title":"Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion","volume":"8","author":"Pedersen","year":"2002","journal-title":"Oral Diseases"},{"key":"2019101604085239400_ref2","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1373\/clinchem.2008.108670","article-title":"Oral fluid testing for drugs of abuse","volume":"55","author":"Bosker","year":"2009","journal-title":"Clinical Chemistry"},{"key":"2019101604085239400_ref3","first-page":"85","volume-title":"Physiology Textbook Series","author":"Davenport","year":"1977"},{"key":"2019101604085239400_ref4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.forsciint.2005.02.028","article-title":"Oral fluid collection: the neglected variable in oral fluid testing","volume":"150","author":"Crouch","year":"2005","journal-title":"Forensic Science International"},{"key":"2019101604085239400_ref5","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/dta.1514","article-title":"Current knowledge on cannabinoids in oral fluid","volume":"6","author":"Lee","year":"2014","journal-title":"Drug Testing and Analysis"},{"key":"2019101604085239400_ref6","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.forsciint.2004.10.026","article-title":"Review: the physiology of saliva and transfer of drugs into saliva","volume":"150","author":"Aps","year":"2005","journal-title":"Forensic Science International"},{"key":"2019101604085239400_ref7","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1067\/mpr.2001.113778","article-title":"A review of saliva: normal composition, flow, and function","volume":"85","author":"Humphrey","year":"2001","journal-title":"The Journal of Prosthetic Dentistry"},{"key":"2019101604085239400_ref8","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1515\/CCLM.2004.248","article-title":"Oral fluid as a diagnostic tool","volume":"42","author":"Choo","year":"2004","journal-title":"Clinical Chemistry and Laboratory Medicine"},{"key":"2019101604085239400_ref9","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/FTD.0b013e318228bb2a","article-title":"Preliminary buprenorphine sublingual tablet pharmacokinetic data in plasma, oral fluid, and sweat during treatment of opioid-dependent pregnant women","volume":"33","author":"Concheiro","year":"2011","journal-title":"Therapeutic Drug Monitoring"},{"key":"2019101604085239400_ref10","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.1365-2125.2008.03252.x","article-title":"The concentration of oxazepam and oxazepam glucuronide in oral fluid, blood and serum after controlled administration of 15 and 30\u00a0mg oxazepam","volume":"66","author":"Smink","year":"2008","journal-title":"British Journal of Clinical Pharmacology"},{"key":"2019101604085239400_ref11","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1093\/jat\/19.6.359","article-title":"Comparison of heroin and cocaine concentrations in saliva with concentrations in blood and plasma","volume":"19","author":"Jenkins","year":"1995","journal-title":"Journal of Analytical Toxicology"},{"key":"2019101604085239400_ref12","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1373\/clinchem.2016.263475","article-title":"Free and glucuronide whole blood cannabinoids' pharmacokinetics after controlled smoked, vaporized, and oral cannabis administration in frequent and occasional cannabis users: identification of recent cannabis intake","volume":"62","author":"Newmeyer","year":"2016","journal-title":"Clinical 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administration","volume":"405","author":"Desrosiers","year":"2013","journal-title":"Analytical and Bioanalytical Chemistry"},{"key":"2019101604085239400_ref16","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1002\/cpt1979256777","article-title":"Creatinine VIII: saliva levels of endogenous \u2018true\u2019 creatinine in normal subjects","volume":"25","author":"Chiou","year":"1979","journal-title":"Clinical Pharmacology and Therapeutics"},{"key":"2019101604085239400_ref17","first-page":"549","article-title":"Correlation of creatinine levels in saliva and plasma in normal subjects and renal patients","volume":"16","author":"Chiou","year":"1977","journal-title":"Research Communications in Chemical Pathology and Pharmacology"},{"key":"2019101604085239400_ref18","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1093\/jat\/bkw057","article-title":"Normalizing oral fluid hydrocodone data using calculated blood 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administration","volume":"63","author":"Newmeyer","year":"2017","journal-title":"Clinical Chemistry"},{"key":"2019101604085239400_ref39","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/dta.1966","article-title":"Cocaine and benzoylecgonine oral fluid on-site screening and confirmation","volume":"8","author":"Ellefsen","year":"2016","journal-title":"Drug Testing and Analysis"},{"key":"2019101604085239400_ref40","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1373\/clinchem.2012.189001","article-title":"On-site test for cannabinoids in oral fluid","volume":"58","author":"Desrosiers","year":"2012","journal-title":"Clinical Chemistry"},{"key":"2019101604085239400_ref41","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/dta.1742","article-title":"Morphine and codeine in oral fluid after controlled poppy seed administration","volume":"7","author":"Concheiro","year":"2015","journal-title":"Drug Testing and 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administration","volume":"27","author":"Barnes","year":"2003","journal-title":"Journal of Analytical Toxicology"},{"key":"2019101604085239400_ref56","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/jat\/bkt009","article-title":"Effects of oral fluid contamination on two oral fluid testing systems","volume":"37","author":"Reichardt","year":"2013","journal-title":"Journal of Analytical Toxicology"},{"key":"2019101604085239400_ref57","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1097\/FTD.0b013e31823d8e8d","article-title":"Which amphetamine-type stimulants can be detected by oral fluid immunoassays?","volume":"34","author":"Souza","year":"2012","journal-title":"Therapeutic Drug Monitoring"},{"key":"2019101604085239400_ref58","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/jat\/bkw060","article-title":"ELISA detection of 30 new amphetamine designer drugs in whole blood, urine and oral fluid using Neogen(R) \u2018Amphetamine\u2019 and \u2018Methamphetamine\/MDMA\u2019 Kits","volume":"40","author":"Nieddu","year":"2016","journal-title":"Journal of Analytical Toxicology"},{"key":"2019101604085239400_ref59","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S1570-0232(02)00400-2","article-title":"Simultaneous, quantitative determination of opiates, amphetamines, cocaine and benzoylecgonine in oral fluid by liquid chromatography quadrupole-time-of-flight mass spectrometry","volume":"779","author":"Mortier","year":"2002","journal-title":"Journal of Chromatography. 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A"},{"key":"2019101604085239400_ref93","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/jat\/bkx079","article-title":"Chiral analysis of methamphetamine in oral fluid samples: a method to distinguish licit from illicit drug use","volume":"42","author":"Borg","year":"2018","journal-title":"Journal of Analytical Toxicology"},{"key":"2019101604085239400_ref94","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S1570-0232(04)00650-6","article-title":"Development and validation of a method for the quantitation of Delta9tetrahydrocannabinol in oral fluid by liquid chromatography electrospray-mass-spectrometry","volume":"810","author":"Concheiro","year":"2004","journal-title":"Journal of Chromatography. 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