{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:53:58Z","timestamp":1761648838787,"version":"3.37.3"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T00:00:00Z","timestamp":1612224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Severe cutaneous adverse drug reactions are uncommon but potentially critical clinical situations demanding prompt diagnosis and treatment. We report a rare and severe case of terbinafine-induced acute generalized pustulosis. The patient was directly referred to a Burn Unit where she underwent diagnostic confirmation, systemic supportive care, and wound care treatments. Clinical and histopathological differential diagnosis of severe cutaneous adverse drug reactions is fundamental due to their significantly different management and prognosis.<\/jats:p>","DOI":"10.1093\/jbcr\/irab023","type":"journal-article","created":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T01:57:22Z","timestamp":1612403842000},"page":"829-831","source":"Crossref","is-referenced-by-count":6,"title":["Terbinafine-Induced Acute Generalized Exanthematous Pustulosis"],"prefix":"10.1093","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0901-0673","authenticated-orcid":false,"given":"Bernardo","family":"Correia","sequence":"first","affiliation":[{"name":"Plastic and Reconstructive Surgery - Burn Unit, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Costa","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery - Burn Unit, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Egipto","sequence":"additional","affiliation":[{"name":"Anesthesiology - Burn Unit, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Reis","sequence":"additional","affiliation":[{"name":"Anesthesiology - Burn Unit, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"key":"2021080411304782900_CIT0001","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1001\/jamadermatol.2018.5605","article-title":"Development and validation of a risk prediction model for in-hospital mortality among patients with Stevens-Johnson syndrome\/toxic epidermal necrolysis-ABCD-10","volume":"155","author":"Noe","year":"2019","journal-title":"JAMA Dermatol"},{"key":"2021080411304782900_CIT0002","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1056\/NEJM199512143332404","article-title":"Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis","volume":"333","author":"Roujeau","year":"1995","journal-title":"N Engl J Med"},{"key":"2021080411304782900_CIT0003","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s11882-018-0778-6","article-title":"Severe cutaneous adverse drug reactions: presentation, risk factors, and management","volume":"18","author":"Mustafa","year":"2018","journal-title":"Curr Allergy Asthma Rep"},{"key":"2021080411304782900_CIT0004","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.jaad.2015.07.017","article-title":"Acute generalized exanthematous pustulosis (AGEP): a review and update","volume":"73","author":"Szatkowski","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"2021080411304782900_CIT0005","first-page":"281","article-title":"Acute generalized exanthematous pustulosis: report of five cases and systematic review of clinical and histopathological findings","volume":"149","author":"Vassallo","year":"2014","journal-title":"G Ital Dermatol Venereol"},{"key":"2021080411304782900_CIT0006","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.bjps.2004.04.025","article-title":"Lyell syndrome revisited: analysis of 18 cases of severe bullous skin disease in a burns unit","volume":"58","author":"Neff","year":"2005","journal-title":"Br J Plast Surg"}],"container-title":["Journal of Burn Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jbcr\/advance-article-pdf\/doi\/10.1093\/jbcr\/irab023\/36434693\/irab023.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jbcr\/article-pdf\/42\/4\/829\/39561947\/irab023.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jbcr\/article-pdf\/42\/4\/829\/39561947\/irab023.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T11:40:18Z","timestamp":1628077218000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbcr\/article\/42\/4\/829\/6126544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,2]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,2,2]]},"published-print":{"date-parts":[[2021,8,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jbcr\/irab023","relation":{},"ISSN":["1559-047X","1559-0488"],"issn-type":[{"type":"print","value":"1559-047X"},{"type":"electronic","value":"1559-0488"}],"subject":[],"published-other":{"date-parts":[[2021,7,1]]},"published":{"date-parts":[[2021,2,2]]}}}