{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:37:34Z","timestamp":1759401454605,"version":"3.37.3"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We aimed to evaluate the characteristics and colonization by pathogenic microorganisms of the ocular surface in patients in a burn center and to determine their association with sedation, mechanical ventilation, and periocular burn. We prospectively evaluated 40 patients during an 8-mo period. Five evaluations where performed, at baseline and weekly on four more occasions or until hospital discharge or death. On each visit, we assessed periocular burn, lid position, Bell\u2019s phenomenon, Schirmer\u2019s test, presence of chemosis, conjunctival hyperemia, and exposure keratopathy; conjunctival fornix swabs were taken for microbiology culture. Also, we documented the level of sedation, mechanical ventilation status, and systemic and ocular treatment. Absent Bell\u2019s phenomenon and chemosis were significantly different at baseline in patients under mechanical ventilation, sedation, and in those with a periocular burn. The cumulative incidence of exposure keratopathy was 22.5% and the cumulative incidence of ocular surface colonization by pathogenic microorganisms was 32.5%. Both outcomes were associated with mechanical ventilation and periocular burn. The most frequent pathogenic microorganisms on the ocular surface were Candida parapsilosis, Acinetobacter baumanii, and Pseudomonas aeuroginosa. We did not observe any case of a persistent epithelial defect, infectious keratitis, corneal perforation or corneal opacity in this cohort. Results from our study may benefit future patients by allowing better risk stratification and treatment strategies for the ocular surface care in burn units.<\/jats:p>","DOI":"10.1093\/jbcr\/irab040","type":"journal-article","created":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T07:57:14Z","timestamp":1615017434000},"page":"43-50","source":"Crossref","is-referenced-by-count":3,"title":["Ocular Surface Characteristics and Colonization in a Burn Center: A Prospective Cohort Study"],"prefix":"10.1093","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7879-7142","authenticated-orcid":false,"given":"Paola","family":"De La Parra-Colin","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Cornea and Ocular Surface Clinic, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Ministry of Health, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Gonzalez-De La Torre","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea and Ocular Surface Clinic, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Ministry of Health, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1574-1138","authenticated-orcid":false,"given":"Rafael","family":"Franco-Cendejas","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Gonzalez-Veliz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea and Ocular Surface Clinic, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Ministry of Health, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vania","family":"Zarza-Garcia","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cornea and Ocular Surface Clinic, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Ministry of Health, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivette Paola","family":"V\u00e1zquez Mellado Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, National Center for Burn Research and Care (CENIAQ), Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda de Lourdes","family":"Garc\u00eda Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0826-9106","authenticated-orcid":false,"given":"Tonatiuh","family":"Barrientos-Gutierrez","sequence":"additional","affiliation":[{"name":"Center for Population Health Research. 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