{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:42:33Z","timestamp":1792734153674,"version":"4.5.0"},"reference-count":94,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This Clinical Practice Guideline addresses early mobilization and rehabilitation (EMR) of critically ill adult burn patients in an intensive care unit (ICU) setting. We defined EMR as any systematic or protocolized intervention that could include muscle activation, active exercises in bed, active resistance exercises, active side-to-side turning, or mobilization to sitting at the bedside, standing, or walking, including mobilization using assistance with hoists or tilt tables, which was initiated within at least 14 days of injury, while the patient was still in an ICU setting. After developing relevant PICO (Population, Intervention, Comparator, Outcomes) questions, a comprehensive literature search was conducted with the help of a professional medical librarian. Available literature was reviewed and systematically evaluated. Recommendations were formulated through the consensus of a multidisciplinary committee, which included burn nurses, physicians, and rehabilitation therapists, based on the available scientific evidence. No recommendation could be formed on the use of EMR to reduce the duration of mechanical ventilation in the burn ICU, but we conditionally recommend the use of EMR to reduce ICU-acquired weakness in critically ill burn patients. No recommendation could be made regarding EMR\u2019s effects on the development of hospital-acquired pressure injuries or disruption or damage to the skin grafts and skin substitutes. We conditionally recommend the use of EMR to reduce delirium in critically ill burn patients in the ICU.<\/jats:p>","DOI":"10.1093\/jbcr\/irac008","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T17:48:32Z","timestamp":1654019312000},"page":"1-15","source":"Crossref","is-referenced-by-count":54,"title":["Clinical Practice Guideline: Early Mobilization and Rehabilitation of Critically Ill Burn Patients"],"prefix":"10.1093","volume":"44","author":[{"given":"Robert","family":"Cartotto","sequence":"first","affiliation":[{"name":"Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, University of Toronto , Ontario , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Johnson","sequence":"additional","affiliation":[{"name":"Burns and Trauma, MedStar Washington Hospital Center, Georgetown University , Washington, DC , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jody M","family":"Rood","sequence":"additional","affiliation":[{"name":"Regions Hospital Burn Center , St. Paul, Minneapolis , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Lorello","sequence":"additional","affiliation":[{"name":"Arizona Burn Center , Glendale, Arizona , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Matherly","sequence":"additional","affiliation":[{"name":"University of Utah Health Burn Center , Salt Lake City, Utah , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Parry","sequence":"additional","affiliation":[{"name":"Shriners Hospital for Children, Northern California, University of California at Davis , Sacramento, California , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Romanowski","sequence":"additional","affiliation":[{"name":"Firefighters Burn Institute Regional Burn Center, University of California at Davis , Sacramento, California , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley","family":"Wiechman","sequence":"additional","affiliation":[{"name":"Regional Burn Center at Harborview, University of Washington , Seattle, Washington , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Bettencourt","sequence":"additional","affiliation":[{"name":"University of Michigan Trauma Burn Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua S","family":"Carson","sequence":"additional","affiliation":[{"name":"Loyola Burn Center , Maywood, Illinois , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry T","family":"Lam","sequence":"additional","affiliation":[{"name":"Sunnybrook Health Sciences Centre , Toronto, Ontario , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Nedelec","sequence":"additional","affiliation":[{"name":"McGill University , Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"2023010803181146800_CIT0001","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13054-020-03446-9","article-title":"Systematic early versus late mobilization or standard mobilization in mechanically ventilated adult ICU patients: systematic review and meta-analysis","volume":"25","author":"Menges","year":"2021","journal-title":"Crit Care"},{"key":"2023010803181146800_CIT0002","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/CCM.0b013e3181cc4b53","article-title":"Intensive care unit acquired weakness","volume":"38","author":"Griffiths","year":"2010","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0003","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1056\/NEJMoa1011802","article-title":"for the","volume":"364","author":"Herridge","year":"2011","journal-title":"New Engl J Med"},{"key":"2023010803181146800_CIT0004","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/ams2.415","article-title":"Postintensive care syndrome: its pathophysiology, prevention, and future directions","volume":"6","author":"Inoue","year":"2019","journal-title":"Acute Med Surg"},{"key":"2023010803181146800_CIT0005","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1097\/CCM.0b013e318232da75","article-title":"Improving long term outcomes after discharge from intensive care unit: report from a stakeholders\u2019 conference","volume":"40","author":"Needham","year":"2012","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0006","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1183\/09031936.00090011","article-title":"Molecular mechanisms of intensive care unit-acquired weakness","volume":"39","author":"Bloch","year":"2012","journal-title":"Eur Respir J"},{"key":"2023010803181146800_CIT0007","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/cc7885","article-title":"Bench-to-bedside review: mobilizing patients in the intensive care unit-from pathophysiology to clinical trials","volume":"13","author":"Truong","year":"2009","journal-title":"Crit Care"},{"key":"2023010803181146800_CIT0008","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0735-1097(03)00848-9","article-title":"Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure","volume":"42","author":"Gielen","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"2023010803181146800_CIT0009","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s40560-019-0413-1","article-title":"Early versus delayed mobilization for in-hospital mortality and health-related quality of life among critically ill patients: a systematic review and meta-analysis","volume":"7","author":"Okada","year":"2019","journal-title":"J Intensive Care"},{"key":"2023010803181146800_CIT0010","first-page":"CD010754","article-title":"Early intervention (mobilization or active exercise) for critically ill adults in the intensive care unit","volume":"3","author":"Doiron","year":"2018","journal-title":"Cochrane Datab Syst Rev"},{"key":"2023010803181146800_CIT0011","doi-asserted-by":"crossref","first-page":"e019998","DOI":"10.1136\/bmjopen-2017-019998","article-title":"Early rehabilitation to prevent postintensive care syndrome in patients with critical illness: a systematic review and meta-analysis","volume":"8","author":"Fuke","year":"2018","journal-title":"BMJ Open"},{"key":"2023010803181146800_CIT0012","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00134-016-4612-0","article-title":"The effects of active mobilisation and rehabilitation in ICU on mortality and function: a systematic review","volume":"43","author":"Tipping","year":"2017","journal-title":"Intensive Care Med"},{"key":"2023010803181146800_CIT0013","doi-asserted-by":"crossref","first-page":"e0130722","DOI":"10.1371\/journal.pone.0130722","article-title":"Effect of early rehabilitation during intensive care unit stay on functional status: systematic review and meta-analysis","volume":"10","author":"Castro-Avila","year":"2015","journal-title":"PLoS One"},{"key":"2023010803181146800_CIT0014","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1097\/CCM.0b013e31827ca637","article-title":"Physical therapy for the critically ill in the ICU: a systematic review and meta-analysis","volume":"41","author":"Kayambu","year":"2013","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0015","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1186\/s13054-014-0658-y","article-title":"Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults","volume":"18","author":"Hodgson","year":"2014","journal-title":"Crit Care"},{"key":"2023010803181146800_CIT0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00101-015-0071-1","article-title":"S2e guideline: positioning and early mobilisation in prophylaxis or therapy of pulmonary disorders: revision 2015: S2e guideline of the German Society of Anaesthesiology and Intensive Care Medicine (DGAI)","volume":"64","author":"Bein","year":"2015","journal-title":"Anaesthetist"},{"key":"2023010803181146800_CIT0017","article-title":"Early mobility guide for reducing ventilator-associated events in mechanically ventilated patients","author":"Agency for Healthcare Research and Quality (AHRQ)","journal-title":"AHRQ Publ No. 1617-0018-4-EF. Baltimore, USA: Johns Hopkins Medicine\/Armstrong Institute for Patient Safety and Quality;"},{"key":"2023010803181146800_CIT0018","doi-asserted-by":"crossref","first-page":"e825","DOI":"10.1097\/CCM.0000000000003299","article-title":"Clinical practice guidelines for the prevention and management of pain, agitation\/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU","volume":"46","author":"Devlin","year":"2018","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0019","author":"National Institute for Health and Care Excellence (NICE).","year":"2018"},{"key":"2023010803181146800_CIT0020","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/ACO.0000000000000568","article-title":"Recent evidence on early mobilization in critically ill patients","volume":"31","author":"Fuest","year":"2018","journal-title":"Curr Opin Anesthesiol"},{"key":"2023010803181146800_CIT0021","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/00000658-200010000-00001","article-title":"Determinants of skeletal muscle catabolism after severe burn","volume":"232","author":"Hart","year":"2000","journal-title":"Ann Surg"},{"key":"2023010803181146800_CIT0022","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0140-6736(16)31469-6","article-title":"The metabolic stress response to burn trauma: current understanding and therapies","volume":"388","author":"Porter","year":"2016","journal-title":"Lancet"},{"key":"2023010803181146800_CIT0023","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1164\/arrd.1980.122.5.731","article-title":"Pulmonary function measurements in patients with thermal injury and smoke inhalation","volume":"122","author":"Whitener","year":"1980","journal-title":"Am Rev Respir Dis"},{"key":"2023010803181146800_CIT0024","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0305-4179(98)00012-6","article-title":"Lung function following thermal injury in children\u2014an 8-year follow up","volume":"24","author":"Mlcak","year":"1998","journal-title":"Burns"},{"key":"2023010803181146800_CIT0025","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/BCR.0b013e31820aafcf","article-title":"Changes in cardiac physiology after severe burn injury","volume":"32","author":"Williams","year":"2011","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0026","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jocn.2018.10.089","article-title":"Neurocognitive sequela of burn injury in the elderly","volume":"59","author":"Esechie","year":"2019","journal-title":"J Clin Neurosci"},{"key":"2023010803181146800_CIT0027","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00004630-200207000-00013","article-title":"Effect of exercise training on pulmonary function in children with thermal injury","volume":"23","author":"Suman","year":"2002","journal-title":"J Burn Care Rehabil"},{"key":"2023010803181146800_CIT0028","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1152\/jappl.2001.91.3.1168","article-title":"Effects of a 12-wk resistance exercise program on skeletal muscle strength in children with burn injuries","volume":"91","author":"Suman","year":"2001","journal-title":"J Appl Physiol"},{"key":"2023010803181146800_CIT0029","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1249\/MSS.0000000000000296","article-title":"Early rehabilitative exercise training in the recovery from pediatric burn","volume":"46","author":"Hardee","year":"2014","journal-title":"Med Sci Sports Exerc"},{"key":"2023010803181146800_CIT0030","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1093\/jbcr\/iry002","article-title":"Strength and cardiorespiratory exercise rehabilitation for severely burned patients during intensive care units: a survey of practice","volume":"39","author":"Cambiaso-Daniel","year":"2018","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0031","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.burns.2016.07.029","article-title":"Effects of mobility training on severe burn patients in the BICU: a retrospective cohort study","volume":"42","author":"Deng","year":"2016","journal-title":"Burns"},{"key":"2023010803181146800_CIT0032","first-page":"S0305","article-title":"Physiotherapeutic and dietetic parameters in burns patients modelling a multidisciplinary approach to burns practice: a bi-disciplinary illustration of interrelated factors","volume":"26","author":"Baytieh","year":"2020","journal-title":"Burns"},{"key":"2023010803181146800_CIT0033","doi-asserted-by":"crossref","first-page":"e205","DOI":"10.1097\/BCR.0000000000000238","article-title":"Reducing the indication for ventilatory support in the severely burned patient: results of a new protocol approach at a regional burn center","volume":"37","author":"Gille","year":"2016","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0034","doi-asserted-by":"crossref","first-page":"186","DOI":"10.2522\/ptj.20110417","article-title":"Effectiveness of an early mobilization protocol in a trauma and burns intensive care unit: a retrospective cohort study","volume":"93","author":"Clark","year":"2013","journal-title":"Phys Therapy"},{"key":"2023010803181146800_CIT0035","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1097\/TA.0000000000002588","article-title":"Impact of an early mobilization protocol on outcome in trauma patients admitted to the intensive care unit: a retrospective pre-post study","volume":"88","author":"Coles","year":"2020","journal-title":"J Trauma Acute Care Surg"},{"key":"2023010803181146800_CIT0036","author":"Law","year":"1998"},{"key":"2023010803181146800_CIT0037","author":"Sch\u00fcnemann"},{"key":"2023010803181146800_CIT0038","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1016\/S0140-6736(09)60658-9","article-title":"Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised control trial","volume":"373","author":"Schweickert","year":"2009","journal-title":"Lancet"},{"key":"2023010803181146800_CIT0039","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1590\/S0103-507X2012000200013","article-title":"Influence of early mobilization on respiratory and peripheral muscle strength in critically ill patients","volume":"24","author":"Dantas","year":"2012","journal-title":"Rev Bras Ter Intensiva"},{"key":"2023010803181146800_CIT0040","doi-asserted-by":"crossref","first-page":"R156","DOI":"10.1186\/cc12835","article-title":"Exercise rehabilitation for patients with critical illness: a randomized controlled trial with 12 months of follow-up","volume":"17","author":"Denehy","year":"2013","journal-title":"Crit Care"},{"key":"2023010803181146800_CIT0041","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1097\/CCM.0b013e3181a38937","article-title":"Early exercise in critically ill patients enhances short-term functional recovery","volume":"37","author":"Burtin","year":"2009","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0042","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/s00134-015-3763-8","article-title":"Early physical rehabilitation in intensive care patients with sepsis syndromes: a pilot randomised controlled trial","volume":"41","author":"Kayambu","year":"2015","journal-title":"Intensive Care Med"},{"key":"2023010803181146800_CIT0043","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1536\/ihj.15-316","article-title":"Early rehabilitation therapy is beneficial for patients with prolonged mechanical ventilation after coronary artery bypass surgery","volume":"57","author":"Dong","year":"2016","journal-title":"Int Heart J"},{"key":"2023010803181146800_CIT0044","doi-asserted-by":"crossref","first-page":"48","DOI":"10.5847\/wjem.j.issn.1920-8642.2014.01.008","article-title":"Effects of early rehabilitation therapy on patients with mechanical ventilation","volume":"5","author":"Dong","year":"2014","journal-title":"World J Emerg Med"},{"key":"2023010803181146800_CIT0045","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1097\/CCM.0000000000001643","article-title":"A binational multicenter pilot feasibility randomized controlled trial of early goal-directed mobilization in ICU","volume":"44","author":"Hodgson","year":"2016","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0046","doi-asserted-by":"crossref","first-page":"e0207428","DOI":"10.1371\/journal.pone.0207428","article-title":"Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: a randomised controlled trial","volume":"13","author":"Eggmann","year":"2018","journal-title":"PLoS One"},{"key":"2023010803181146800_CIT0047","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s13054-016-1199-3","article-title":"Muscle mass, strength and functional outcomes in critically ill patients after cardiothoracic surgery: does neuromuscular electrical stimulation help? The Catastim 2 randomized controlled trial","volume":"20","author":"Fischer","year":"2016","journal-title":"Crit Care"},{"key":"2023010803181146800_CIT0048","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.1001\/jama.2016.7201","article-title":"Standardized rehabilitation and hospital length of stay among patients with acute respiratory failure: a randomized clinical trial","volume":"315","author":"Morris","year":"2016","journal-title":"JAMA"},{"key":"2023010803181146800_CIT0049","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/s00134-013-3136-0","article-title":"Feasibility and safety of early combined cognitive and physical therapy for critically ill medical and surgical patients: the Activity and Cognitive Therapy in ICU (ACT-ICU) trial","volume":"40","author":"Brummel","year":"2014","journal-title":"Intensive Care Med"},{"key":"2023010803181146800_CIT0050","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/S0140-6736(16)31637-3","article-title":"Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial","volume":"388","author":"Schaller","year":"2016","journal-title":"Lancet"},{"key":"2023010803181146800_CIT0051","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1016\/j.apmr.2017.01.028","article-title":"Intensive early rehabilitation in the intensive care unit for liver transplant recipients: a randomized controlled trial","volume":"98","author":"Maffei","year":"2017","journal-title":"Arch Phys Med Rehabil"},{"key":"2023010803181146800_CIT0052","doi-asserted-by":"crossref","first-page":"R74","DOI":"10.1186\/cc8987","article-title":"Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial","volume":"14","author":"Routsi","year":"2010","journal-title":"Crit Care"},{"key":"2023010803181146800_CIT0053","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/crj.12091","article-title":"Effect of physical therapy on muscle strength, respiratory muscles and functional parameters in patients with intensive care unit-acquired weakness","volume":"9","author":"Yosef-Brauner","year":"2015","journal-title":"Clin Respir J"},{"key":"2023010803181146800_CIT0054","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1164\/rccm.201505-1039OC","article-title":"A randomized trial of an intensive physical therapy program for acute respiratory failure patients","volume":"193","author":"Moss","year":"2016","journal-title":"Am J Resp Crit Care Med"},{"key":"2023010803181146800_CIT0055","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S0003-9993(98)90369-0","article-title":"Rehabilitation of patients admitted to a respiratory intensive care unit","volume":"79","author":"Nava","year":"1998","journal-title":"Arch Phys Med Rehabil"},{"key":"2023010803181146800_CIT0056","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.2522\/ptj.20050036","article-title":"Effects of physical training on functional status in patients with prolonged mechanical ventilation","volume":"86","author":"Chiang","year":"2006","journal-title":"Phys Ther"},{"key":"2023010803181146800_CIT0057","doi-asserted-by":"crossref","first-page":"338","DOI":"10.4037\/ajcc2019264","article-title":"Hospital acquired pressure injuries in critical care and progressive care: avoidable versus unavoidable","volume":"28","author":"Pittman","year":"2019","journal-title":"Am J Crit Care"},{"key":"2023010803181146800_CIT0058","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.aucc.2020.12.001","article-title":"Prevalence of pressure injuries among critically ill patients and factors associated with the occurrence in the intensive care unit: the PRESSURE study","volume":"34","author":"Jaq","year":"2021","journal-title":"Aust Crit Care"},{"key":"2023010803181146800_CIT0059","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/BCR.0b013e31825d5538","article-title":"Pressure ulcers and risk assessment in severe burns","volume":"33","author":"Lewis","year":"2012","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0060","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1093\/jbcr\/irab061","article-title":"Using pressure mapping to optimize hospital acquired pressure injury prevention strategies in the burn intensive care unit","volume":"42","author":"Yesanthrao","year":"2021","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0061","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/iwj.13516","article-title":"Can an early mobilization programme prevent hospital-acquired pressure injuries in an intensive care unit? A systematic review and meta-analysis","volume":"18","author":"Nieto-Garc\u00eda","year":"2021","journal-title":"Int Wound J"},{"key":"2023010803181146800_CIT0062","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/nicc.12455","article-title":"The effect of early mobilization in critically ill patients: a meta-analysis","volume":"25","author":"Zang","year":"2020","journal-title":"Nurs Crit Care"},{"key":"2023010803181146800_CIT0063","first-page":"CD009958","article-title":"Repositioning for pressure injury in adults","volume":"6","author":"Gillespie","year":"2020","journal-title":"Cochran Database of Syst. Rev"},{"key":"2023010803181146800_CIT0064","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s41038-019-0151-6","article-title":"Joint contractures in severe burn patients with early rehabilitation intervention in one of the largest burn intensive care unit in China: a descriptive analysis","volume":"7","author":"Tan","year":"2019","journal-title":"Burn Trauma"},{"key":"2023010803181146800_CIT0065","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/j.burns.2020.10.023","article-title":"Early physiotherapy experience with a biodegradable polyurethane dermal substitute: therapy guidelines for use","volume":"47","author":"Schmitt","year":"2021","journal-title":"Burns"},{"key":"2023010803181146800_CIT0066","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/BCR.0b013e31823359d9","article-title":"Practice guidelines for early ambulation of burn survivors after lower extremity grafts","volume":"33","author":"Nedelec","year":"2012","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0067","first-page":"431","article-title":"Results of aprospective randomized controlled trial of early ambulation for patients with lower extremity autografts","volume":"35","author":"Lorello","year":"2014","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0068","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/01.JAT.0000462351.77719.26","article-title":"Early mobilization of patients after split-thickness skin grafting to the lower extremities with the use of subatmospheric pressure wound therapy","volume":"6","author":"Franczyk","year":"2015","journal-title":"J Acute Care Phys Ther"},{"key":"2023010803181146800_CIT0069","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1440-0960.2011.00829.x","article-title":"Effect of early and late mobilisation on split skin graft outcome","volume":"53","author":"Luczak","year":"2012","journal-title":"Australas J Dermatol"},{"key":"2023010803181146800_CIT0070","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.burns.2017.07.005","article-title":"Early ambulation after-grafting of lower extremity burns","volume":"44","author":"Gawaziuk","year":"2018","journal-title":"Burns"},{"key":"2023010803181146800_CIT0071","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1093\/jbcr\/iry003","article-title":"The impact of time of mobilization after split thickness skin graft on lower extremity wound healing \u2013 systematic review and meta-analysis","volume":"39","author":"Retrouvey","year":"2018","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0072","author":"Mayo Foundation for Medical Education and Research.","year":"2020"},{"key":"2023010803181146800_CIT0073","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1177\/089198878800100302","article-title":"Delirium in the elderly","volume":"1","author":"Beresin","year":"1988","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"2023010803181146800_CIT0074","doi-asserted-by":"crossref","first-page":"474","DOI":"10.7326\/0003-4819-119-6-199309150-00005","article-title":"A predictive model for delirium in hospitalized elderly medical patients based on admission characteristics","volume":"119","author":"Inouye","year":"1993","journal-title":"Ann Intern Med"},{"key":"2023010803181146800_CIT0075","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1001\/jama.1996.03530350034031","article-title":"Precipitating factors for delirium in hospitalized elderly persons. Predictive model and interrelationship with baseline vulnerability","volume":"275","author":"Inouye","year":"1996","journal-title":"JAMA"},{"key":"2023010803181146800_CIT0076","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1525-1497.1998.00047.x","article-title":"Delirium risk factors in elderly hospitalized patients","volume":"13","author":"Elie","year":"1998","journal-title":"J Gen Intern Med"},{"key":"2023010803181146800_CIT0077","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1097\/01.CCM.0000164540.58515.BF","article-title":"Delirium as detected by the CAMICU predicts restraint use among mechanically ventilated medical patients","volume":"33","author":"Micek","year":"2005","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0078","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/cc7892","article-title":"Risk factors for delirium in intensive care patients: a prospective cohort study","volume":"13","author":"Van Rompaey","year":"2009","journal-title":"Crit Care"},{"key":"2023010803181146800_CIT0079","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.apmr.2010.01.002","article-title":"Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project","volume":"91","author":"Needham","year":"2010","journal-title":"Arch Phys Med Rehabil"},{"key":"2023010803181146800_CIT0080","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1001\/jama.300.14.1685","article-title":"Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function","volume":"300","author":"Needham","year":"2008","journal-title":"JAMA"},{"key":"2023010803181146800_CIT0081","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1056\/NEJM199903043400901","article-title":"A multicomponent intervention to prevent delirium in hospitalized older patients","volume":"340","author":"Inouye","year":"1999","journal-title":"New Engl J Med"},{"key":"2023010803181146800_CIT0082","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/CCM.0b013e3182783b72","article-title":"Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit","volume":"41","author":"Barr","year":"2013","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0083","doi-asserted-by":"crossref","first-page":"e825","DOI":"10.1097\/CCM.0000000000003299","article-title":"Clinical practice guidelines for the prevention and management of pain, agitation\/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU","volume":"46","author":"Devlin","year":"2018","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0084","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/MCC.0b013e3283427243","article-title":"Sedation, delirium, and mechanical ventilation: the \u201cABCDE\u201d approach","volume":"17","author":"Morandi","year":"2011","journal-title":"Curr Opin Crit Care"},{"key":"2023010803181146800_CIT0085","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1378\/chest.10-0466","article-title":"Reducing iatrogenic risks: ICU acquired delirium and weakness\u2014crossing the quality chasm","volume":"138","author":"Vasilevskis","year":"2010","journal-title":"Chest"},{"key":"2023010803181146800_CIT0086","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/CCM.0b013e3181f245d3","article-title":"A screening, prevention, and restoration model for saving the injured brain in intensive care unit survivors","volume":"38","author":"Vasilevskis","year":"2010","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0087","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4037\/ccn2012229","article-title":"Critical care nurses\u2019 role in implementing the \u201cABCDE bundle\u201d into practice","volume":"32","author":"Balas","year":"2012","journal-title":"Crit Care Nurse"},{"key":"2023010803181146800_CIT0088","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1097\/CCM.0000000000000129","article-title":"Effectiveness and safety of the awakening and breathing coordination, delirium monitoring\/management, and early exercise\/mobility bundle","volume":"42","author":"Balas","year":"2014","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0089","author":"Society of Critical Care Medicine (SCCM)"},{"key":"2023010803181146800_CIT0090","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/CCM.0000000000003482","article-title":"Caring for critically ill patients with the ABCDEF bundle: results of the ICU liberation collaborative in over 15,000 adults","volume":"47","author":"Pun","year":"2019","journal-title":"Crit Care Med"},{"key":"2023010803181146800_CIT0091","doi-asserted-by":"crossref","first-page":"S80","DOI":"10.1093\/jbcr\/irab032.124","article-title":"A survey of burn care professionals to characterize patterns of early mobility in ICU burn patients","volume":"42","author":"Higgins","year":"2021","journal-title":"J Burn Care Res"},{"key":"2023010803181146800_CIT0092","doi-asserted-by":"crossref","first-page":"E448","DOI":"10.9778\/cmajo.20160021","article-title":"Early mobilization of critically ill adults: a survey of knowledge perceptions and practices of Canadian physicians and physiotherapists","volume":"4","author":"Koo","year":"2016","journal-title":"CMAJ Open"},{"key":"2023010803181146800_CIT0093","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0004-9514(14)60294-4","article-title":"Physiotherapy following cardiac surgery: is it necessary during the intubation period?","volume":"47","author":"Patman","year":"2001","journal-title":"Aust J Physiother"},{"key":"2023010803181146800_CIT0094","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.4037\/ajcc2017297","article-title":"Organizational domains and variations in attitudes of intensive care providers towards the ABCDE bundle","volume":"26","author":"Boehm","year":"2017","journal-title":"Am J Crit Care"}],"container-title":["Journal of Burn Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jbcr\/advance-article-pdf\/doi\/10.1093\/jbcr\/irac008\/44242745\/irac008.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbcr\/advance-article-pdf\/doi\/10.1093\/jbcr\/irac008\/48514684\/irac008.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbcr\/advance-article-pdf\/doi\/10.1093\/jbcr\/irac008\/48514684\/irac008.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T03:20:30Z","timestamp":1673148030000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbcr\/article\/44\/1\/1\/6590256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,26]]},"references-count":94,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,5,26]]},"published-print":{"date-parts":[[2023,1,5]]}},"URL":"https:\/\/doi.org\/10.1093\/jbcr\/irac008","relation":{},"ISSN":["1559-047X","1559-0488"],"issn-type":[{"value":"1559-047X","type":"print"},{"value":"1559-0488","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,1,1]]},"published":{"date-parts":[[2022,5,26]]}}}