{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:42:31Z","timestamp":1791499351316,"version":"4.3.4"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Massive burn injuries are a unique patient population with unique treatment paradigms. Data from 155 adult patients, admitted from 2009 to 2019, with &amp;gt;50% total body surface area burns (TBSA) were collected and analyzed. Average burn size was 70% TBSA and 63% had a concomitant inhalation injury. Approximately 30% of patients (46\/155) transitioned to comfort care-only measures within 24 hours of admission. Standard treatment patients were younger (37 \u00b1 13 vs 60 \u00b1 19 years; p &amp;lt; .00001), male (94% vs 28%; p = .001) and had smaller TBSA (66 \u00b1 13 vs 80 \u00b1 16; p &amp;lt; .00001). Of the standard treatment group, 72 (66%) survived to discharge. Survivors had smaller TBSA (64 \u00b1 13 vs 71 \u00b1 13; p = .003), less third-degree TBSA (48 \u00b1 25 vs 71 \u00b1 13; p = .003) and lower incidence of renal failure requiring dialysis (22% vs 73%, p &amp;lt; .00001). Multivariate regression analysis showed that age (OR 1.05; p = .025), total TBSA (OR 1.07; p = .005), and renal failure (OR 10.2; p = .00005) were independently associated with mortality. Inhalation injury was not significantly associated with mortality. About 23% (35\/155) of patients had a psychiatric condition on admission and 19% (30\/155) of patients were burned attempting suicide. Patients with psychiatric conditions spent more time in the hospital (62 vs 30 days; p = .004), more time on ventilator (31 vs 12 days; p = .046), underwent more surgery (4 vs 2 operations, p = .03), and were less likely to die (34% vs 59%; p = .02). In summary, age, burn size, and renal failure were independently associated with mortality, with renal failure being the strongest factor. Psychiatric conditions are prevalent pre-injury and tend to require more inpatient care.<\/jats:p>","DOI":"10.1093\/jbcr\/irac173","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T13:09:11Z","timestamp":1668517751000},"page":"925-930","source":"Crossref","is-referenced-by-count":13,"title":["Massive Burn Injuries: Characteristics and Outcomes From a Single Institution"],"prefix":"10.1093","volume":"44","author":[{"given":"J","family":"Heard","sequence":"first","affiliation":[{"name":"Burn Division, Department of Surgery University of California Davis , Sacramento, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Cronin","sequence":"additional","affiliation":[{"name":"Burn Division, Department of Surgery University of California Davis , Sacramento, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Romanowski","sequence":"additional","affiliation":[{"name":"Burn Division, Department of Surgery University of California Davis , Sacramento, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Greenhalgh","sequence":"additional","affiliation":[{"name":"Burn Division, Department of Surgery University of California Davis , Sacramento, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Palmieri","sequence":"additional","affiliation":[{"name":"Burn Division, Department of Surgery University of California Davis , Sacramento, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Sen","sequence":"additional","affiliation":[{"name":"Burn Division, Department of Surgery University of California Davis , Sacramento, California ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,11,15]]},"reference":[{"key":"2025121801222597900_CIT0001","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.burns.2006.10.002","article-title":"Burns in Sweden: an analysis of 24,538 cases during the period 1987-2004","volume":"33","author":"Akerlund","year":"2007","journal-title":"Burns J Int Soc Burn Inj"},{"key":"2025121801222597900_CIT0002","volume-title":"Web-Based Injury Statistics Query and Reporting System (WISQARS) [Online]","author":"Center for Disease Control and Prevention.","year":"2022"},{"key":"2025121801222597900_CIT0003","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1016\/j.burns.2014.03.003","article-title":"Epidemiology and trends in severe burns in the Netherlands","volume":"40","author":"Dokter","year":"2014","journal-title":"Burns J Int Soc Burn Inj"},{"key":"2025121801222597900_CIT0004","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1097\/BCR.0B013E318148C9AC","article-title":"National study of Emergency Department visits for burn injuries, 1993 to 2004","volume":"28","author":"Fagenholz","year":"2007","journal-title":"J Burn Care Res Off Publ Am Burn Assoc"},{"key":"2025121801222597900_CIT0005","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.burns.2011.06.005","article-title":"Epidemiology of burns throughout the world. 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