{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:47:47Z","timestamp":1790894867871,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T00:00:00Z","timestamp":1698278400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Burn management has significantly advanced in the past 75 years, resulting in improved mortality rates. However, there are still over one million burn victims in the United States each year, with over 3,000 burn-related deaths annually. The impacts of individual patient, hospital, and regional demographics on length of stay (LOS) and total cost have yet to be fully explored in a large nationally representative cohort. Thus, this study aimed to examine various hospital and patient characteristics using a sample of over 20,000 patients. Inpatient data from the National Inpatient Sample from 2008 to 2015 were analyzed, and only patients with an ICD-9 code for second- or third-degree burns were included. In addition, a major operating room procedure must have been indicated on the discharge summary for patients to be included in the final dataset, ensuring that only severe burns requiring complex care were analyzed. Analysis of covariance models was used to evaluate the impact of various patient, hospital, and regional variables on both LOS and cost. The study found that skin grafts and fasciotomy significantly increased the cost of hospitalization. Having burns on the face, neck, and trunk significantly increased costs for patients with second-degree burns, while burns on the trunk resulted in the longest LOS for patients with third-degree burns. Infections in the hospital and additional procedures, such as flaps and skin grafts, also led to longer stays. The study also found that the prevalence of postoperative complications, such as electrolyte imbalance, was high among patients with burn surgery.<\/jats:p>","DOI":"10.1093\/jbcr\/irad168","type":"journal-article","created":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T12:28:13Z","timestamp":1698323293000},"page":"425-431","source":"Crossref","is-referenced-by-count":10,"title":["Understanding the Drivers of Cost and Length of Stay in a Cohort of 21,875 Patients with Severe Burn"],"prefix":"10.1093","volume":"45","author":[{"given":"Sacha C","family":"Hauc","sequence":"first","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola Antonia","family":"St\u00f6gner","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]},{"name":"Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Burn Center, Hannover Medical School , Hannover ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6187-8605","authenticated-orcid":false,"given":"Jacqueline M","family":"Ihnat","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helia","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4795-0225","authenticated-orcid":false,"given":"Lioba","family":"Huelsboemer","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Kauke-Navarro","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean C","family":"Rivera","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5388-2017","authenticated-orcid":false,"given":"Mica","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3607-1340","authenticated-orcid":false,"given":"Joshua Z","family":"Glahn","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7710-3276","authenticated-orcid":false,"given":"Alisa","family":"Savetamal","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3703-8240","authenticated-orcid":false,"given":"Bohdan","family":"Pomahac","sequence":"additional","affiliation":[{"name":"Department of Surgery, Plastic and Reconstructive Surgery, Yale School of Medicine , New Haven, 06511, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,10,26]]},"reference":[{"issue":"2 Suppl 1","key":"2025052403470820200_CIT0001","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1097\/SAP.0000000000000896","article-title":"History and advancement of burn treatments","volume":"78","author":"Liu","year":"2017","journal-title":"Ann Plast Surg"},{"issue":"1","key":"2025052403470820200_CIT0002","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s13287-019-1203-3","article-title":"Skin tissue regeneration for burn injury","volume":"10","author":"Shpichka","year":"2019","journal-title":"Stem Cell Res Ther"},{"issue":"24","key":"2025052403470820200_CIT0003","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1056\/NEJMra1807442","article-title":"Management of burns","volume":"380","author":"Greenhalgh","year":"2019","journal-title":"N Engl J Med"},{"issue":"2","key":"2025052403470820200_CIT0004","first-page":"175","article-title":"Therapeutic use of stem cells in treatment of burn injuries","volume":"39","author":"Cheng","year":"2018","journal-title":"J Burn Care Res"},{"issue":"2","key":"2025052403470820200_CIT0005","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/ALN.0000000000000559","article-title":"Acute and perioperative care of the burn-injured 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