{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T04:02:12Z","timestamp":1784865732351,"version":"3.55.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Pulmonary insufficiency is the primary cause of death in cases of major burns accompanied by inhalation damage. It is important to consider the impact on the face and neck in flame burns. Early implementation of bronchial hygiene measures and oxygenation treatment in inhalation injury can reduce mortality. This case series presents the effects of high-flow nasal oxygen (HFNO) application on patient outcomes in major burns and inhalation injury. This report discusses 3 different patients. One patient, a 29-year-old male with 35% TBSA burns, received HFNO treatment for inhalation injury on the sixth day after the trauma. After 72 hours of HFNO application, the patient\u2019s pulmonary symptoms improved. The second patient had 60% TBSA burns and developed respiratory distress symptoms on the fifth day after the trauma. After 7 days of HFNO application, all symptoms and findings of acute respiratory distress syndrome (ARDS) were resolved. HFNO has been used for the treatment of ARDS related to major burn (60% of burned TBSA) in a 28-year-old patient, and improvement was achieved. The use of HFNO in pulmonary insufficiency among burn patients has not been reported previously. This series of patient cases demonstrates the successful application of HFNO in treating inhalation injury and burn-related ARDS. However, further clinical studies are necessary to increase its clinical utilization.<\/jats:p>","DOI":"10.1093\/jbcr\/irae066","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T22:50:40Z","timestamp":1713394240000},"page":"1060-1065","source":"Crossref","is-referenced-by-count":2,"title":["New Treatment Modality for Burn Injury-Related Acute Respiratory Distress Syndrome: High-Flow Nasal Oxygen Therapy in Major Burns"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7224-4774","authenticated-orcid":false,"given":"Merve","family":"Ak\u0131n","sequence":"first","affiliation":[{"name":"General Surgery, Burn Treatment Unit, Ankara City Hospital , Ankara, 06800 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0764-6248","authenticated-orcid":false,"given":"Huriye Bilge","family":"Tuncer","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation, Ankara City Hospital , Ankara, 06800 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0389-4922","authenticated-orcid":false,"given":"Ali Emre","family":"Akg\u00fcn","sequence":"additional","affiliation":[{"name":"General Surgery, Burn Treatment Unit, Ankara City Hospital , Ankara, 06800 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1211-9354","authenticated-orcid":false,"given":"Ezgi","family":"Erk\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation, Ankara City Hospital , Ankara, 06800 , Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"key":"2024082909572169900_CIT0001","first-page":"8","article-title":"Teamwork for total burn care: burn centers and multidisciplinary burn teams","volume-title":"Total Burn Care","author":"Janos","year":"2018","edition":"5"},{"key":"2024082909572169900_CIT0002","first-page":"36","article-title":"Burn management in disasters and humanitarian crises","volume-title":"Total Burn Care","author":"Herbert","year":"2018","edition":"5"},{"key":"2024082909572169900_CIT0003","first-page":"221","article-title":"Host defense antibacterial effector cells influenced by massive burns","volume-title":"Total Burn Care","author":"Makiko","year":"2018","edition":"5"},{"key":"2024082909572169900_CIT0004","first-page":"174","article-title":"The pathophysiology of inhalation injury","volume-title":"Total Burn Care","author":"Perenlei","year":"2018","edition":"5"},{"key":"2024082909572169900_CIT0005","first-page":"195","article-title":"Respiratory care","volume-title":"Total Burn Care","author":"Ronald","year":"2018","edition":"5"},{"issue":"2","key":"2024082909572169900_CIT0006","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S2213-2600(21)00414-8","article-title":"Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research","volume":"10","author":"Weerakkody","year":"2022","journal-title":"The Lancet. 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