{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:17:54Z","timestamp":1784132274481,"version":"3.55.0"},"reference-count":127,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:00:00Z","timestamp":1714608000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The global increasing spread of multidrug-resistant organisms (MDROs) is threatening the control of various infections in vulnerable populations and patient groups. One of the most affected groups is patients with burns, who are prone to hyperinfection as they suffer from a hypermetabolic state and weaken immune barriers. Those patients also share the infection risk of patients hospitalized for a long time, including ventilator-associated pneumonia and urinary tract infections. While some preventative and therapeutic management styles are still controversial, we discuss consensuses here. In this review, we aim to present the current knowledge on multidrug resistance with a special focus on patients with burns, discuss various causative organisms and their treatment options, and highlight the importance of antibiotic stewardship and teamwork in responding to an outbreak of MDROs.<\/jats:p>","DOI":"10.1093\/jbcr\/irae075","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T08:05:39Z","timestamp":1714637139000},"page":"877-886","source":"Crossref","is-referenced-by-count":14,"title":["Multidrug-Resistant Organisms: The Silent Plight of Burn Patients"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5811-9907","authenticated-orcid":false,"given":"Randa","family":"Elsheikh","sequence":"first","affiliation":[{"name":"Deanery of Biomedical Sciences at Edinburgh Medical School, University of Edinburgh , Edinburgh EH8 9YL , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2011-8092","authenticated-orcid":false,"given":"Abdelrahman M","family":"Makram","sequence":"additional","affiliation":[{"name":"School of Public Health, Imperial College London , London SW7 2AZ , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,2]]},"reference":[{"issue":"2","key":"2024080703330604200_CIT0001","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.burns.2016.08.013","article-title":"Recent trends in burn epidemiology worldwide: a systematic review","volume":"43","author":"Smolle","year":"2017","journal-title":"Burns"},{"issue":"4","key":"2024080703330604200_CIT0002","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1093\/jbcr\/irac160","article-title":"prevalence of multi drug resistant organism in ICU burns patients at tertiary care 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