{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T01:59:11Z","timestamp":1791079151649,"version":"4.1.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pediatric burn injuries can lead to both acute procedural distress and longer-term psychological challenges, including anxiety, depression, and post-traumatic stress symptoms. While physical rehabilitation is well integrated into burn care, mental health interventions remain underutilized and inconsistently applied. This systematic review and meta-analysis evaluate procedural and psychological strategies used to improve mental health and pain-related outcomes in pediatric burn survivors. A comprehensive search of PubMed, Embase, and Scopus was conducted for studies published from January 2000 to December 2023. Eligible studies included pediatric burn patients (\u226418\u00a0years) and evaluated interventions targeting either acute pain\/anxiety during wound care or longer-term psychological recovery. Random-effects meta-analyses were performed for studies reporting extractable continuous outcomes. Heterogeneity was assessed using I2 and \u03c42 statistics. Twenty-four studies involving 1705 pediatric burn patients were included. Interventions addressed either procedural distress (eg, virtual reality [VR], music therapy) or psychological sequelae (eg, cognitive-behavioral therapy, pharmacologic treatments, school-based support).VR demonstrated a significant and consistent effect in reducing procedural pain, with a pooled standardized mean difference (SMD) of \u22120.95 (95% CI, \u22121.31 to \u22120.59, P &amp;lt; .0001, I2\u2009=\u20090%). Music therapy showed a nonsignificant pooled effect (SMD\u2009=\u2009\u22120.47, 95% CI, \u22126.62 to 5.69, P = .51, I2\u2009=\u200980.8%), though individual studies suggested benefits in older children or when paired with physical therapy. Cognitive-behavioral, creative, and psychosocial interventions showed promise but varied in effectiveness. Virtual reality is a robust, nonpharmacological intervention for procedural pain management in pediatric burn care. However, robust evidence supporting interventions for long-term psychological outcomes remains limited.<\/jats:p>","DOI":"10.1093\/jbcr\/iraf190","type":"journal-article","created":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:46:07Z","timestamp":1760269567000},"page":"519-530","source":"Crossref","is-referenced-by-count":3,"title":["Pain, Distress, and Psychological Sequelae in Pediatric Burn Care: A Systematic Review and Meta-Analysis of Interventions Across the Care Continuum"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9552-6483","authenticated-orcid":false,"given":"Antoinette","family":"Nguyen","sequence":"first","affiliation":[{"name":"University of Rochester School of Medicine and Dentistry , Rochester, NY 14620 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishika","family":"Chikoti","sequence":"additional","affiliation":[{"name":"University of Rochester School of Medicine and Dentistry , Rochester, NY 14620 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek","family":"Bell","sequence":"additional","affiliation":[{"name":"University of Rochester School of Medicine and Dentistry , Rochester, NY 14620 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"2026030600223493000_ref1","doi-asserted-by":"publisher","first-page":"13","DOI":"10.2147\/PHMT.S288154","article-title":"Clinical profile of pediatric burn patients in burn care unit of Halibet hospital in 2018: Asmara, Eritrea","volume":"12","author":"Mohammed","year":"2021","journal-title":"Pediatric Health Med Ther"},{"key":"2026030600223493000_ref2","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1136\/bmj.329.7462.391","article-title":"ABC of burns. 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