{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T19:09:04Z","timestamp":1788808144559,"version":"build-2803163510"},"reference-count":26,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Diabetes mellitus causes vascular dysfunction, immune dysregulation, and cellular abnormalities. Prior studies suggest worse outcomes in patients with burn injuries and diabetes mellitus but are limited by single-institution studies and small sample sizes. National databases like the Burn Care Quality Platform (BCQP) can provide higher-powered multi-institutional datasets to determine outcomes otherwise unseen. Using the BCQP, adult patients with burn injuries admitted for burn care from 2016 to 2018 were retrospectively reviewed for diabetes status. Primary outcomes were time to 95% wound closure. Secondary outcomes were hospital and intensive care unit (ICU) length of stay (LOS), rates of acute respiratory distress syndrome (ARDS), ventilator-associated pneumonia (VAP), central line\u2013associated bloodstream infection (CLABSI), operative intervention rates, and in-hospital mortality. Patients with diabetes had longer wound closure time (25 vs 22\u00a0days; P\u2009=\u2009.0006) and more operative procedures (15.8 vs 1.3; P\u2009&amp;lt;\u2009.0001) than nondiabetic patients. Patients with diabetes also had longer hospital LOS (8 vs 5\u00a0days; P\u2009&amp;lt;\u2009.0001) and higher mortality (5.7% vs 4.1%; P\u2009=\u2009.045) than nondiabetic patients, with no differences in ARDS, VAP, or CLABSI. On multivariable analysis, diabetes mellitus itself was not an independent predictor of complications or mortality, but early hyperglycemia was the strongest modifiable predictor of ARDS, VAP, and CLABSI. Overall, diabetes mellitus was associated with delayed wound healing, longer hospital LOS, and ICU LOS. Acute complications were driven by early hyperglycemia following admission and injury severity, highlighting early glycemic optimization in burn care.<\/jats:p>","DOI":"10.1093\/jbcr\/irag149","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T11:36:18Z","timestamp":1787052978000},"source":"Crossref","is-referenced-by-count":0,"title":["Impact of Diabetes Mellitus on Wound Healing and Clinical Outcomes After Burn Injury: An Analysis Using the Burn Care Quality Platform"],"prefix":"10.1093","author":[{"given":"Arthur","family":"Kom Sipowa","sequence":"first","affiliation":[{"name":"Firefighters\u2019 Burn and Surgical Research Laboratory, MedStar Health Research Institute , Washington, DC 20010 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Furcolo","sequence":"additional","affiliation":[{"name":"Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuan D","family":"Le","sequence":"additional","affiliation":[{"name":"Firefighters\u2019 Burn and Surgical Research Laboratory, MedStar Health Research Institute , Washington, DC 20010 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa M","family":"McLawhorn","sequence":"additional","affiliation":[{"name":"Firefighters\u2019 Burn and Surgical Research Laboratory, MedStar Health Research Institute , Washington, DC 20010 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie C","family":"Carney","sequence":"additional","affiliation":[{"name":"Firefighters\u2019 Burn and Surgical Research Laboratory, MedStar Health Research Institute , Washington, DC 20010 ,","place":["United States"]},{"name":"Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]},{"name":"Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren T","family":"Moffatt","sequence":"additional","affiliation":[{"name":"Firefighters\u2019 Burn and Surgical Research Laboratory, MedStar Health Research Institute , Washington, DC 20010 ,","place":["United States"]},{"name":"Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]},{"name":"Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey W","family":"Shupp","sequence":"additional","affiliation":[{"name":"Firefighters\u2019 Burn and Surgical Research Laboratory, MedStar Health Research Institute , Washington, DC 20010 ,","place":["United States"]},{"name":"Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]},{"name":"Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]},{"name":"Department of Surgery, Georgetown University School of Medicine , Washington, DC 20007,","place":["United States"]},{"name":"The Burn Center, Department of Surgery, MedStar Washington Hospital Center , Washington, DC 20010 ,","place":["United States"]},{"name":"Department of Plastic and Reconstructive Surgery, Georgetown University School of Medicine , Washington, DC 20010 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5478-8935","authenticated-orcid":false,"given":"Shawn","family":"Tejiram","sequence":"additional","affiliation":[{"name":"Firefighters\u2019 Burn and Surgical Research Laboratory, MedStar Health Research Institute , Washington, DC 20010 ,","place":["United States"]},{"name":"Georgetown University School of Medicine , Washington, DC 20007 ,","place":["United States"]},{"name":"Department of Surgery, Georgetown University School of Medicine , Washington, DC 20007,","place":["United States"]},{"name":"The Burn Center, Department of Surgery, MedStar Washington Hospital Center , Washington, DC 20010 ,","place":["United States"]},{"name":"Department of Plastic and Reconstructive Surgery, Georgetown University School of Medicine , Washington, DC 20010 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"2026090714562713100_ref1","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1097\/BCR.0b013e3182700025","article-title":"The relationship between acute and chronic hyperglycemia and outcomes in burn injury","volume":"34","author":"Murphy","year":"2013","journal-title":"J Burn Care 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