{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T14:31:18Z","timestamp":1793802678977,"version":"4.6.1"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Burn injuries during pregnancy are associated with significant maternal and fetal morbidity and mortality; however, available evidence is fragmented and largely based on small observational studies.<\/jats:p>\n                  <jats:p>To estimate pooled maternal and fetal mortality among pregnant women with burn injuries and explore the impact of burn severity.<\/jats:p>\n                  <jats:p>A systematic review and meta-analysis of proportions was conducted following PRISMA 2020 guidelines. PubMed\/MEDLINE, Scopus, Web of Science, and LILACS were searched from inception to March 2026. Observational studies and case series reporting maternal and\/or fetal outcomes were included. Risk of bias was assessed using Newcastle\u2013Ottawa Scale and Joanna Briggs Institute tools, and certainty of evidence using Grading of Recommendations Assessment, Development and Evaluation. Random-effects models with Freeman\u2013Tukey double arcsine transformation were applied.<\/jats:p>\n                  <jats:p>Results: Twenty-two studies including 1162 pregnant women were analyzed. Most studies were case series (n\u2009=\u200915), followed by cohort studies (n\u2009=\u20095) one cross-sectional study, and one case report. Maternal mortality ranged from 0% to 70%. The pooled maternal mortality proportion was 0.43 (95% CI, 0.36-0.50), with substantial heterogeneity (I2\u00a0=\u200972.9%). Fetal mortality ranged from 31.3% to 90.5%, with a pooled estimate of 0.57 (95% CI, 0.49-0.65; I2\u00a0=\u200978.6%). Burn severity, particularly TBSA burned \u226550%, was consistently associated with worse outcomes. Funnel plots suggested possible publication bias. The overall certainty of evidence was low. Burn injuries during pregnancy are associated with high maternal and fetal mortality, strongly influenced by burn severity. Despite consistent findings, the low certainty of evidence highlights the need for high-quality prospective studies.<\/jats:p>","DOI":"10.1093\/jbcr\/irag155","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T17:22:07Z","timestamp":1787937727000},"page":"1746-1756","source":"Crossref","is-referenced-by-count":0,"title":["Maternal and Fetal Outcomes in Pregnant Women with Burn Injuries: A Systematic Review and Meta-Analysis"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8985-4266","authenticated-orcid":false,"given":"Juan Jose Parra","family":"Molina","sequence":"first","affiliation":[{"name":"Universidad Industrial de Santander , Bucaramanga, Santander ,","place":["Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7706-6006","authenticated-orcid":false,"given":"Sergio","family":"Romero","sequence":"additional","affiliation":[{"name":"Universidad Industrial de Santander , Bucaramanga, Santander ,","place":["Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3634-8821","authenticated-orcid":false,"given":"Edgar Fabian Manrique","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Universidad Industrial de Santander , Bucaramanga, Santander ,","place":["Colombia"]},{"name":"Hospital Internacional de Colombia HIC - Fundaci\u00f3n Cardiovascular de Colombia FCV - Fundaci\u00f3n Universitaria FCV , Piedecuesta ,","place":["Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"2026110409173161700_ref1","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.burns.2005.10.003","article-title":"Burns in pregnancy","volume":"32","author":"Maghsoudi","year":"2006","journal-title":"Burns"},{"key":"2026110409173161700_ref2","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.ijgo.2008.10.003","article-title":"Burn injuries during pregnancy in Iran","volume":"104","author":"Karimi","year":"2009","journal-title":"Int J Gynaecol Obstet"},{"key":"2026110409173161700_ref3","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.burns.2004.07.005","article-title":"Burnt pregnant wives: a social stigma","volume":"31","author":"Mago","year":"2005","journal-title":"Burns."},{"key":"2026110409173161700_ref4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1080\/01443610120101646","article-title":"Severe burn injury in pregnancy in northern Nigeria","volume":"22","author":"Chama","year":"2002","journal-title":"J Obstet Gynaecol"},{"key":"2026110409173161700_ref5","doi-asserted-by":"publisher","first-page":"QC01","DOI":"10.7860\/JCDR\/2022\/57694.17305","article-title":"Foetomaternal outcome in pregnancy with burn injury: a prospective cohort study","volume":"16","author":"Ambedkar","year":"2022","journal-title":"J Clin Diagn Res"},{"key":"2026110409173161700_ref6","first-page":"392","article-title":"Major burns during pregnancy: effects on fetal well-being","volume":"63","author":"Rayburn","year":"1984","journal-title":"Obstet Gynecol"},{"key":"2026110409173161700_ref7","first-page":"434","article-title":"Thermal injury during pregnancy","volume":"47","author":"Taylor","year":"1976","journal-title":"Obstet Gynecol"},{"key":"2026110409173161700_ref8","first-page":"209","article-title":"Thermal injury in the pregnant patient","volume":"161","author":"Amy","year":"1985","journal-title":"Surg Gynecol Obstet"},{"key":"2026110409173161700_ref9","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/0301-2115(95)02272-4","article-title":"A retrospective study of 11 pregnant women with thermal injuries","volume":"64","author":"Unsur","year":"1996","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2026110409173161700_ref10","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0305-4179(94)90066-3","article-title":"Burns in pregnancy: effect on maternal and fetal outcomes","volume":"20","author":"Akhtar","year":"1994","journal-title":"Burns."},{"key":"2026110409173161700_ref11","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1093\/jbcr\/irae177","article-title":"Burns during pregnancy: is the outcome still gloomy? A follow-up case series","volume":"46","author":"Mabrouk","year":"2025","journal-title":"J Burn Care Res"},{"key":"2026110409173161700_ref12","first-page":"90","article-title":"Maternal and fetal outcome of burn during pregnancy: 3rd report from Kermanshah, Iran","volume":"11","author":"Seyedzadeh","year":"2021","journal-title":"Int J Burns Trauma"},{"key":"2026110409173161700_ref13","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1016\/j.burns.2020.04.005","article-title":"Pregnancy and burns: guidelines for safe management","volume":"46","author":"Karimi","year":"2020","journal-title":"Burns."},{"key":"2026110409173161700_ref14","doi-asserted-by":"publisher","first-page":"226","DOI":"10.5005\/jp-journals-10006-1932","article-title":"Assessment of maternal and fetal outcomes of burn in pregnancy","volume":"13","author":"Sapre","year":"2021","journal-title":"J South Asian Fed Obstet Gynaecol"},{"key":"2026110409173161700_ref15","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1111\/j.1471-0528.1982.tb04712.x","article-title":"Obstetric implications of burns in pregnancy","volume":"89","author":"Matthews","year":"1982","journal-title":"Br J Obstet Gynaecol"},{"key":"2026110409173161700_ref16","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/0305-4179(92)90154-M","article-title":"Management of thermal injury in pregnancy: an analysis of 16 patients","volume":"18","author":"Gang","year":"1992","journal-title":"Burns."},{"key":"2026110409173161700_ref17","author":"Rayyan"},{"key":"2026110409173161700_ref18","author":"Newcastle-Ottawa Scale (NOS)"},{"key":"2026110409173161700_ref19","author":"Critical appraisal tools"},{"key":"2026110409173161700_ref20","author":"GRADE"},{"key":"2026110409173161700_ref21","author":"Documentation"},{"key":"2026110409173161700_ref22","first-page":"174","article-title":"Maternal and foetal outcome of burns during pregnancy in Kermanshah, Iran","volume":"19","author":"Rezavand","year":"2006","journal-title":"Ann Burns Fire Disasters"},{"key":"2026110409173161700_ref23","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1007\/s13224-017-1021-4","article-title":"Feto-maternal outcomes in pregnancies complicated by thermal burns","volume":"68","author":"Mittal","year":"2018","journal-title":"J Obstet Gynaecol India"},{"key":"2026110409173161700_ref24","first-page":"196","article-title":"Evaluation of maternal and foetal outcomes in pregnant women hospitalized in Kermanshah hospitals, Iran, owing to burn injury, 2003-2008","volume":"25","author":"Rezavand","year":"2012","journal-title":"Ann Burns Fire Disasters"},{"key":"2026110409173161700_ref25","first-page":"153","article-title":"Epidemiology of burns during pregnancy in southern Iran: effect on maternal and fetal outcomes","volume":"28","author":"Pasalar","year":"2013","journal-title":"World Appl Sci J"},{"key":"2026110409173161700_ref26","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1016\/j.burns.2015.10.001","article-title":"Epidemiology of burns during pregnancy in Tehran","volume":"42","author":"Vaghardoost","year":"2016","journal-title":"Iran Burns"},{"key":"2026110409173161700_ref27","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/S0305-4179(97)00055-7","article-title":"Burns during pregnancy: a gloomy outcome","volume":"23","author":"Mabrouk","year":"1997","journal-title":"Burns."}],"container-title":["Journal of Burn Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jbcr\/advance-article-pdf\/doi\/10.1093\/jbcr\/irag155\/70830271\/irag155.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbcr\/article-pdf\/47\/6\/1746\/70830271\/irag155.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbcr\/article-pdf\/47\/6\/1746\/70830271\/irag155.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T14:17:37Z","timestamp":1793801857000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbcr\/article\/47\/6\/1746\/8772592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,28]]},"references-count":27,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,8,28]]},"published-print":{"date-parts":[[2026,11,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jbcr\/irag155","relation":{},"ISSN":["1559-047X","1559-0488"],"issn-type":[{"value":"1559-047X","type":"print"},{"value":"1559-0488","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,11]]},"published":{"date-parts":[[2026,8,28]]}}}