{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:30:38Z","timestamp":1782844238765,"version":"3.54.5"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,16]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In Nepal, burn is the third most common injury after falls and road traffic accidents. Infection is the leading cause of mortality in burn injury. A profile exploring predominant flora and antimicrobial sensitivity is important to facilitate treatment ahead of microbiology results and to aid prevention of multidrug-resistant organisms. The aim of this study was to document epidemiological and bacteriological data of burn wound infections at a tertiary level burns center in Nepal. Samples were collected from January 2017 to May 2017, over a period of 5 months. Patient notes were referred to and information regarding baseline characteristics and burn wound infection data was collected. A total of 76 patients were included in the study during the 5-month period, which resulted in 113 samples being included for review. Females were injured most with burns 70% (n = 53) compared with males 30% (n = 23). Only 6 (8%) of 77 patients lived locally in Kathmandu. The average distance traveled by patients was 233 km (median 208, range 0\u2013765, SD 181). Average TBSA% of burn was 22% (median 20, range 3\u201350, SD 12). Gram-negative organisms predominated, with Acinetobacter spp. in 42 cases (55%), Pseudomonas aeruginosa in 26 cases (34%), and Enterobacter spp. in 16 cases (21%). Colistin, polymyxin B, and tigecycline were found to be most sensitive covering 108, 98, and 94 organisms. Gram-negative bacteria colonized the majority of burn wounds. Colistin, polymyxin B, and tigecycline were the most sensitive to gram-negative bacteria. Gram-positive Staphylococcus aureus was sensitive most to vancomycin and tigecycline.<\/jats:p>","DOI":"10.1093\/jbcr\/irz096","type":"journal-article","created":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T02:49:45Z","timestamp":1560480585000},"page":"838-845","source":"Crossref","is-referenced-by-count":19,"title":["The Bacteriological Profile of Burn Wound Infections at a Tertiary Burns Center in Nepal"],"prefix":"10.1093","volume":"40","author":[{"given":"Ojas Jyoti Singh","family":"Pujji","sequence":"first","affiliation":[{"name":"Department of General Surgery, The Royal Wolverhampton NHS Trust, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran Kishor","family":"Nakarmi","sequence":"additional","affiliation":[{"name":"Department of Burns, Plastic and Reconstructive Surgery, Kirtipur Hospital, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basudha","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Kathmandu Hospital, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shankar Man","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Burns, Plastic and Reconstructive Surgery, Kirtipur Hospital, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven Leonard Alexander","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Department of Burns and Plastic Surgery, The Queen Elizabeth Hospital, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,6,13]]},"reference":[{"key":"2019101713492495600_CIT0001","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1128\/CMR.19.2.403-434.2006","article-title":"Burn wound infections","volume":"19","author":"Church","year":"2006","journal-title":"Clin Microbiol Rev"},{"key":"2019101713492495600_CIT0002","unstructured":"World Health Organization. 2017. Burns (online). 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