{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T04:56:20Z","timestamp":1679633780935},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To determine the imaging characteristics and stability over time of sternal lesions identified on breast MRI in patients without history of cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>An IRB-approved retrospective analysis of all breast MRIs performed at our institution from September 1, 2017 to December 1, 2021 that included one of several key words related to the sternum. Studies with history of non-dermatologic malignancy including breast cancer, absence of a true sternal lesion, or presence of symptoms during the examination were excluded. Imaging was reviewed for size, distribution, signal characteristics, and presence of contrast enhancement, perilesional edema, periosteal edema, or intralesional fat. Available comparison imaging, clinical history, and follow-up recommendations were reviewed. Descriptive statistics were used to summarize lesion data.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 60 lesions included from 60 patients, 40 lesions with more than two years of comparison imaging were either stable or decreased in size and none demonstrated change in signal characteristics. The majority of these presumed benign lesions demonstrated hypointense signal on T1-weighted sequences (21\/40, 52.5%), hyperintense signal on fluid-sensitive sequences (33\/40, 82.5%), contrast enhancement (32\/40, 80.0%), and absence of clear intralesional fat (29\/40, 72.5%). One patient who did not have comparison imaging was diagnosed with malignancy (multiple myeloma) eight months following their MRI. This lesion demonstrated uniquely diffuse and heterogeneous enhancement but did not undergo biopsy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Sternal lesions in women without history of non-dermatologic malignancy have a very low likelihood of malignancy. Common imaging characteristics of the presumed benign lesions can inform imaging recommendations when incidental sternal lesions are discovered.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jbi\/wbac078","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T19:42:24Z","timestamp":1671738144000},"page":"48-55","source":"Crossref","is-referenced-by-count":1,"title":["A Retrospective Analysis of Sternal Lesions Detected on Breast MRI in Patients Without History of Cancer"],"prefix":"10.1093","volume":"5","author":[{"given":"Aaron","family":"Jen","sequence":"first","affiliation":[{"name":"Brigham and Women\u2019s Hospital and Harvard Medical School, Department of Radiology , Boston, MA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanne","family":"Kochkodan-Self","sequence":"additional","affiliation":[{"name":"Brigham and Women\u2019s Hospital and Harvard Medical School, Department of Radiology , Boston, MA , 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