{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T14:39:11Z","timestamp":1772548751799,"version":"3.50.1"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the utility of SCOUT radar localization (SCOUT) placement at the time of axillary lymph node (LN) biopsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was conducted on SCOUT placement during axillary LN core-needle biopsy (CNB) between January 2018 and September 2023. The SCOUT was considered utilized if detected and removed during targeted axillary dissection with or without subsequent axillary LN dissection. Analysis was performed with a Fisher\u2019s exact test and Wilcoxon rank-sum test to determine association of features with either LN disease status or SCOUT utilization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>SCOUT placement was performed in 127 patients during US-guided CNB, with 77% (98\/127) malignant and 23% (29\/127) benign results. Three patients were lost to follow-up and excluded. SCOUTs placed during LN biopsy were utilized in 70% (87\/124) of patients. A total of 104 patients underwent axillary surgery, including 80 malignant and 24 benign CNB specimen cases. The SCOUT-localized node did not take up blue dye or radiotracer in 28% (22\/80) of patients with malignant CNB LNs, 86% (19\/22) of whom were in postneoadjuvant treatment. SCOUTs were not utilized for 30% (37\/124) of patients. Age was a significant predictor of SCOUT utilization, with 87% (40\/46) of utilization among patients &amp;lt;50 years old (P &amp;lt;.001). Among the 24 patients with benign CNB specimens who underwent axillary surgery, 25% (6\/24) had nodal metastasis, of which 50% (3\/6) were within the SCOUT-localized node.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SCOUTs placed at the time of LN biopsy facilitate detection of the biopsied node and may be particularly beneficial after neoadjuvant treatment and in women &amp;lt;50 years old.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jbi\/wbaf049","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T11:21:32Z","timestamp":1754306492000},"page":"32-41","source":"Crossref","is-referenced-by-count":0,"title":["SCOUT Localization at Time of Lymph Node Biopsy"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3832-1649","authenticated-orcid":false,"given":"Meng","family":"Hao","sequence":"first","affiliation":[{"name":"Department of Radiology, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5026-371X","authenticated-orcid":false,"given":"Steven P","family":"Poplack","sequence":"additional","affiliation":[{"name":"Department of Radiology, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of Surgery, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tie","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Radiology, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0545-5165","authenticated-orcid":false,"given":"Brittany Z","family":"Dashevsky","sequence":"additional","affiliation":[{"name":"Department of Radiology, Stanford University , Stanford, CA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"issue":"22","key":"2026030305341414000_wbaf049-B1","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1001\/jama.1996.03540220042028","article-title":"Lymphatic mapping and sentinel node biopsy in the patient with breast cancer","volume":"276","author":"Albertini","year":"1996","journal-title":"JAMA"},{"issue":"6","key":"2026030305341414000_wbaf049-B2","doi-asserted-by":"publisher","first-page":"691","DOI":"10.6004\/jnccn.2022.0030","article-title":"Breast Cancer, version 3.2022, NCCN Clinical Practice Guidelines in oncology","volume":"20","author":"Gradishar","year":"2022","journal-title":"J Natl Compr Canc Netw"},{"issue":"10","key":"2026030305341414000_wbaf049-B3","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/S1470-2045(10)70207-2","article-title":"Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial","volume":"11","author":"Krag","year":"2010","journal-title":"Lancet Oncol"},{"issue":"5","key":"2026030305341414000_wbaf049-B4","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1053\/j.semnuclmed.2022.01.006","article-title":"Sentinel lymph node methods in breast cancer","volume":"52","author":"Giammarile","year":"2022","journal-title":"Semin Nucl Med"},{"issue":"4","key":"2026030305341414000_wbaf049-B5","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S1470-2045(13)70035-4","article-title":"Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial","volume":"14","author":"Galimberti","year":"2013","journal-title":"Lancet Oncol"},{"issue":"10","key":"2026030305341414000_wbaf049-B6","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1001\/jama.2017.11470","article-title":"Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis: the ACOSOG Z0011 (Alliance) randomized clinical trial","volume":"318","author":"Giuliano","year":"2017","journal-title":"JAMA"},{"issue":"6","key":"2026030305341414000_wbaf049-B7","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1001\/jama.2011.90","article-title":"Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial","volume":"305","author":"Giuliano","year":"2011","journal-title":"JAMA"},{"issue":"14","key":"2026030305341414000_wbaf049-B8","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1001\/jama.2013.278932","article-title":"Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: the ACOSOG Z1071 (Alliance) clinical trial","volume":"310","author":"Boughey","year":"2013","journal-title":"JAMA"},{"issue":"4","key":"2026030305341414000_wbaf049-B9","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1097\/SLA.0000000000001375","article-title":"Identification and resection of clipped node decreases the false-negative rate of sentinel lymph node surgery in patients presenting with node-positive breast cancer (T0-T4, N1-N2) who receive neoadjuvant chemotherapy: results from ACOSOG Z1071 (Alliance)","volume":"263","author":"Boughey","year":"2016","journal-title":"Ann Surg"},{"issue":"10","key":"2026030305341414000_wbaf049-B10","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1200\/JCO.2015.64.0094","article-title":"Improved axillary evaluation following neoadjuvant therapy for patients with node-positive breast cancer using selective evaluation of clipped nodes: implementation of targeted axillary dissection","volume":"34","author":"Caudle","year":"2016","journal-title":"J Clin Oncol"},{"issue":"10","key":"2026030305341414000_wbaf049-B11","doi-asserted-by":"publisher","first-page":"3011","DOI":"10.1245\/s10434-017-6023-z","article-title":"Localizing the clipped node in patients with node-positive breast cancer treated with neoadjuvant chemotherapy: early learning experience and challenges","volume":"24","author":"Nguyen","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"2026030305341414000_wbaf049-B12","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.clinimag.2017.10.003","article-title":"Lymph node wire localization post-chemotherapy: towards improving the false negative sentinel lymph node biopsy rate in breast cancer patients","volume":"48","author":"Dashevsky","year":"2018","journal-title":"Clin Imaging"},{"issue":"4","key":"2026030305341414000_wbaf049-B13","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.clinimag.2017.10.003","article-title":"Clinical utility of axillary nodal markers in breast cancer","volume":"49","author":"Barry","year":"2023","journal-title":"Eur J Surg Oncol"},{"issue":"4","key":"2026030305341414000_wbaf049-B14","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.3390\/cancers15041173","article-title":"Localization techniques for non-palpable breast lesions: current status, knowledge gaps, and rationale for the MELODY study (EUBREAST-4\/iBRA-NET, NCT 05559411)","volume":"15","author":"Banys-Paluchowski","year":"2023","journal-title":"Cancers"},{"key":"2026030305341414000_wbaf049-B15","first-page":"348","article-title":"Innovative diagnostics for breast cancer: new frontiers for the new millennium using radioactive seed localization","volume":"1999","author":"Dauway"},{"issue":"11","key":"2026030305341414000_wbaf049-B16","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.1016\/j.ejso.2019.06.035","article-title":"Is the future magnetic? Magseed localisation for non palpable breast cancer. A multi-centre non randomised control study","volume":"45","author":"Zacharioudakis","year":"2019","journal-title":"Eur J Surg Oncol"},{"issue":"2","key":"2026030305341414000_wbaf049-B17","doi-asserted-by":"publisher","first-page":"e008","DOI":"10.1097\/as9.0000000000000008","article-title":"Effectiveness and Safety of Magseed-localization for excision of breast lesions: a prospective, phase IV trial","volume":"1","author":"Singh","year":"2020","journal-title":"Ann Surg Open"},{"issue":"4","key":"2026030305341414000_wbaf049-B18","doi-asserted-by":"publisher","first-page":"W69","DOI":"10.2214\/AJR.15.15962","article-title":"Evaluation of the SAVI SCOUT surgical guidance system for localization and excision of nonpalpable breast lesions: a feasibility study","volume":"207","author":"Mango","year":"2016","journal-title":"AJR Am J Roentgenol"},{"issue":"7","key":"2026030305341414000_wbaf049-B19","doi-asserted-by":"publisher","first-page":"3633","DOI":"10.21873\/anticanres.14352","article-title":"Savi Scout\u00ae radar localisation of non-palpable breast lesions: systematic review and pooled analysis of 842 Cases","volume":"40","author":"Kasem","year":"2020","journal-title":"Anticancer Res"},{"issue":"4","key":"2026030305341414000_wbaf049-B20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.37549\/AR-D-24-0001","article-title":"A practical guide to wireless breast localization devices","volume":"53","author":"Sabato","year":"2024","journal-title":"Appl Radiol"},{"key":"2026030305341414000_wbaf049-B21","author":"Krause"},{"issue":"3","key":"2026030305341414000_wbaf049-B22","doi-asserted-by":"publisher","first-page":"e189","DOI":"10.1016\/j.clbc.2020.08.001","article-title":"Feasibility of axillary lymph node localization and excision using radar reflector localization","volume":"21","author":"Sun","year":"2021","journal-title":"Clin Breast Cancer"},{"key":"2026030305341414000_wbaf049-B23","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.clinimag.2022.07.007","article-title":"Ultrasound-guided radar reflector localization of axillary lymph nodes facilitates targeted axillary dissection","volume":"90","author":"Weinfurtner","year":"2022","journal-title":"Clin Imaging"},{"issue":"4","key":"2026030305341414000_wbaf049-B24","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1093\/jbi\/wbae024","article-title":"SCOUT\u00ae radar localization at time of breast biopsy","volume":"6","author":"Dashevsky","year":"2024","journal-title":"J Breast Imaging"},{"key":"2026030305341414000_wbaf049-B25","first-page":"29","volume-title":"Breast Imaging","author":"D\u2019Orsi","year":"2018"},{"issue":"3","key":"2026030305341414000_wbaf049-B26","doi-asserted-by":"publisher","first-page":"399","DOI":"10.2214\/AJR.22.28399","article-title":"Image-guided radar reflector localization for small soft-tissue lesions in the musculoskeletal system","volume":"220","author":"Burke","year":"2023","journal-title":"AJR Am J Roentgenol"},{"issue":"6","key":"2026030305341414000_wbaf049-B27","doi-asserted-by":"publisher","first-page":"3916","DOI":"10.1245\/s10434-024-15142-x","article-title":"Cost-effectiveness of radar localisation versus wire localisation for wide local excision of non-palpable breast cancer","volume":"31","author":"Nguyen","year":"2024","journal-title":"Ann Surg Oncol"},{"issue":"9","key":"2026030305341414000_wbaf049-B28","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1016\/j.ultrasmedbio.2017.05.003","article-title":"Axillary lymph node sonographic features and breast tumor characteristics as predictors of malignancy: a nomogram to predict risk","volume":"43","author":"Akissue de Camargo Teixeira","year":"2017","journal-title":"Ultrasound Med Biol"},{"issue":"3","key":"2026030305341414000_wbaf049-B29","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1200\/JCO.2014.55.7827","article-title":"Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study","volume":"33","author":"Boileau","year":"2015","journal-title":"J Clin Oncol"},{"issue":"1","key":"2026030305341414000_wbaf049-B30","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1245\/s10434-017-6090-1","article-title":"Pre-operative axillary ultrasound-guided needle sampling in breast cancer: comparing the sensitivity of fine needle aspiration cytology and core needle biopsy","volume":"25","author":"Topps","year":"2018","journal-title":"Ann Surg Oncol"},{"issue":"11","key":"2026030305341414000_wbaf049-B31","doi-asserted-by":"publisher","first-page":"3102","DOI":"10.1245\/s10434-007-9494-5","article-title":"Preoperative identification of the sentinel lymph node in breast cancer","volume":"14","author":"Nathanson","year":"2007","journal-title":"Ann Surg Oncol"},{"key":"2026030305341414000_wbaf049-B32","doi-asserted-by":"publisher","first-page":"100207","DOI":"10.1016\/j.clinsp.2023.100207","article-title":"The effectiveness of ultrasound-guided core needle biopsy in detecting lymph node metastases in the axilla in patients with breast cancer: systematic review and meta-analysis","volume":"78","author":"Xu","year":"2023","journal-title":"Clinics (Sao Paulo)"},{"issue":"1","key":"2026030305341414000_wbaf049-B33","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.breast.2008.09.003","article-title":"Ultrasound guided percutaneous axillary lymph node core biopsy: how often is the sentinel lymph node being biopsied?","volume":"18","author":"Britton","year":"2009","journal-title":"Breast"},{"issue":"4","key":"2026030305341414000_wbaf049-B34","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1001\/jamaoncol.2016.4163","article-title":"Axillary nodal management following neoadjuvant chemotherapy","volume":"3","author":"Pilewskie","year":"2017","journal-title":"JAMA Oncol"},{"issue":"7","key":"2026030305341414000_wbaf049-B35","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/S1470-2045(13)70166-9","article-title":"Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study","volume":"14","author":"Kuehn","year":"2013","journal-title":"Lancet Oncol"}],"container-title":["Journal of Breast Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jbi\/article-pdf\/8\/1\/32\/66844538\/wbaf049.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbi\/article-pdf\/8\/1\/32\/66844538\/wbaf049.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T10:34:16Z","timestamp":1772534056000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbi\/article\/8\/1\/32\/8471620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,10]]},"published-print":{"date-parts":[[2026,3,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jbi\/wbaf049","relation":{},"ISSN":["2631-6110","2631-6129"],"issn-type":[{"value":"2631-6110","type":"print"},{"value":"2631-6129","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1]]},"published":{"date-parts":[[2026,1]]}}}