{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:31:43Z","timestamp":1788827503487,"version":"build-2803163510"},"reference-count":29,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:00:00Z","timestamp":1784937600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluates concordance between abbreviated protocol breast MRIs (abMRI) and standard full-protocol MRI in the post-neoadjuvant chemotherapy (NAC) setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multi-site single institution retrospective study included breast cancer patients with pre- and post-NAC breast MRI during 2016-2023. The abMRI sequences included localizers, pre-contrast fat sat T1, fat sat first post-contrast phase, reconstructed first post-contrast phase subtraction, and maximum-intensity projection images from the institution\u2019s standard protocol. Four breast radiologists interpreted abMRIs and full MRIs after a washout period of at least 1 month. Residual tumor size (RTS) was compared to pathology. Statistical analysis with multivariable logistic regression, Receiver Operating Curve analysis, Kappa analysis, and paired t-tests were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Ninety-two of 237 patients (38.8%; mean age, 52.6 years) had pathologic complete response (pCR). There was no significant difference between abMRI and full MRI for predicting pCR for any reader individually (P-value range 0.30\u20130.91) with overall area under curve (AUC) = 0.70. Intraobserver and interobserver agreement for abMRI and full MRI was moderate to good (\u03ba = 0.52\u20130.78). There was concordance between abMRI and full MRI for predicting pCR when stratified by menopause status, background parenchymal enhancement, tumor stage, tumor biomarkers, and Ki-67. When compared to pathology, all readers demonstrated no significant difference in RTS with abMRI, and one reader underestimated RTS on full MRI by 7\u2005mm (P = 0.005).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study found no significant difference in diagnostic performance between abMRI and full MRI when compared to pathology for evaluating post-NAC patients for pCR and evaluation of residual disease in the breast. Abbreviated MRI and full MRI show similar effectiveness in predicting complete tumor response and assessing residual disease on post-NAC assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jbi\/wbag033","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T11:47:42Z","timestamp":1779968862000},"source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Abbreviated Breast MRI Following Neoadjuvant Chemotherapy"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1394-6543","authenticated-orcid":false,"given":"Iris","family":"Chen","sequence":"first","affiliation":[{"name":"University of California Los Angeles, Department of Radiological Sciences , Los Angeles, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Linden","sequence":"additional","affiliation":[{"name":"University of California Los Angeles, Department of Radiological Sciences , Los Angeles, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6090-8713","authenticated-orcid":false,"given":"James","family":"Sayre","sequence":"additional","affiliation":[{"name":"University of California Los Angeles, Department of Radiological Sciences , Los Angeles, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kendall","family":"Clark","sequence":"additional","affiliation":[{"name":"University of California Los Angeles, Department of Radiological Sciences , Los Angeles, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Dascalos","sequence":"additional","affiliation":[{"name":"University of California Los Angeles, Department of Radiological Sciences , Los Angeles, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4046-038X","authenticated-orcid":false,"given":"Hannah","family":"Milch","sequence":"additional","affiliation":[{"name":"University of California Los Angeles, Department of Radiological Sciences , Los Angeles, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Joines","sequence":"additional","affiliation":[{"name":"University of California Los Angeles, Department of Radiological Sciences , Los Angeles, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,25]]},"reference":[{"key":"2026072511263347600_wbag033-B1","doi-asserted-by":"publisher","first-page":"8705531","DOI":"10.1155\/2022\/8705531","article-title":"A Concise Review on the Utilization of Abbreviated Protocol Breast MRI over Full Diagnostic Protocol in Breast Cancer Detection","volume":"2022","author":"Ewaidat","year":"2022","journal-title":"Int J Biomed Imaging"},{"issue":"22","key":"2026072511263347600_wbag033-B2","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1200\/JCO.2013.52.5386","article-title":"Abbreviated Breast Magnetic Resonance Imaging (MRI): First Postcontrast Subtracted Images and Maximum-Intensity Projection\u2014A Novel Approach to Breast Cancer Screening With MRI","volume":"32","author":"Kuhl","year":"2014","journal-title":"J Clin Oncol"},{"issue":"2","key":"2026072511263347600_wbag033-B3","doi-asserted-by":"publisher","first-page":"154.e23","DOI":"10.1016\/j.crad.2020.08.036","article-title":"A meta-analysis comparing the diagnostic performance of abbreviated MRI and a full diagnostic protocol in breast cancer","volume":"76","author":"Baxter","year":"2021","journal-title":"Clin Radiol"},{"issue":"2","key":"2026072511263347600_wbag033-B4","doi-asserted-by":"publisher","first-page":"284","DOI":"10.2214\/AJR.16.17205","article-title":"Abbreviated MRI Protocols: Wave of the Future for Breast Cancer Screening","volume":"208","author":"Chhor","year":"2017","journal-title":"AJR Am J Roentgenol"},{"issue":"6","key":"2026072511263347600_wbag033-B5","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1148\/rg.2020200006","article-title":"Abbreviated and Ultrafast Breast MRI in Clinical Practice","volume":"40","author":"Gao","year":"2020","journal-title":"Radiographics."},{"issue":"2","key":"2026072511263347600_wbag033-B6","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1148\/radiol.2018172868","article-title":"Dynamic Contrast-enhanced Breast MRI for Evaluating Residual Tumor Size after Neoadjuvant Chemotherapy","volume":"289","author":"Kim","year":"2018","journal-title":"Radiology."},{"issue":"3","key":"2026072511263347600_wbag033-B7","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1148\/radiol.2015150006","article-title":"Breast Cancer: Influence of Taxanes on Response Assessment with Dynamic Contrast-enhanced MR Imaging","volume":"277","author":"Schrading","year":"2015","journal-title":"Radiology."},{"issue":"3","key":"2026072511263347600_wbag033-B8","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1148\/radiol.2016160176","article-title":"Neoadjuvant Systemic Therapy in Breast Cancer: Association of Contrast-enhanced MR Imaging Findings, Diffusion-weighted Imaging Findings, and Tumor Subtype with Tumor Response","volume":"283","author":"Santamar\u00eda","year":"2017","journal-title":"Radiology."},{"issue":"10","key":"2026072511263347600_wbag033-B9","doi-asserted-by":"publisher","first-page":"e0222917","DOI":"10.1371\/journal.pone.0222917","article-title":"Higher underestimation of tumour size post-neoadjuvant chemotherapy with breast magnetic resonance imaging (MRI)\u2014A concordance comparison cohort analysis","volume":"14","author":"Wu","year":"2019","journal-title":"PLoS One."},{"issue":"10","key":"2026072511263347600_wbag033-B10","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.2174\/1573405618666220223142009","article-title":"Abbreviated and Standard Breast MRI in Neoadjuvant Chemotherapy Response Evaluation: A Comparative Study","volume":"18","author":"Yirgin","year":"2022","journal-title":"Curr Med Imaging."},{"issue":"6","key":"2026072511263347600_wbag033-B11","doi-asserted-by":"publisher","first-page":"817","DOI":"10.2214\/AJR.22.28686","article-title":"Abbreviated Versus Full-Protocol MRI for Breast Cancer Neoadjuvant Chemotherapy Response Assessment: Diagnostic Performance by General and Breast Radiologists","volume":"220","author":"Tang","year":"2023","journal-title":"AJR Am J Roentgenol."},{"issue":"3","key":"2026072511263347600_wbag033-B12","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1148\/rg.2021200134","article-title":"Breast MRI for Evaluation of Response to Neoadjuvant Therapy","volume":"41","author":"Reig","year":"2021","journal-title":"Radiographics."},{"issue":"2","key":"2026072511263347600_wbag033-B13","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.ejca.2008.10.026","article-title":"New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)","volume":"45","author":"Eisenhauer","year":"2009","journal-title":"Eur J Cancer."},{"issue":"9","key":"2026072511263347600_wbag033-B14","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1038\/modpathol.2015.74","article-title":"Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group","volume":"28","author":"Provenzano","year":"2015","journal-title":"Mod Pathol."},{"issue":"1","key":"2026072511263347600_wbag033-B15","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics."},{"issue":"3","key":"2026072511263347600_wbag033-B16","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1159\/000543958","article-title":"Evaluation of Interreader Agreement between Optimized Short and Full Breast MRI Protocols for Screening Breast Cancer in Moderate- and High-Risk Women","volume":"20","author":"Lopes Da Silva Filho","year":"2025","journal-title":"Breast Care (Basel)."},{"key":"2026072511263347600_wbag033-B17","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.clinimag.2023.06.007","article-title":"Can breast MRI predict pathologic response following neoadjuvant chemotherapy for breast cancer? A retrospective cohort study","volume":"101","author":"Kwak","year":"2023","journal-title":"Clin Imaging."},{"issue":"6","key":"2026072511263347600_wbag033-B18","doi-asserted-by":"publisher","first-page":"e15516","DOI":"10.7759\/cureus.15516","article-title":"Diagnostic Accuracy of MRI in Evaluating Response After Neoadjuvant Systemic Therapy in Operable Breast Cancer","volume":"13","author":"Khazindar","year":"2021","journal-title":"Cureus."},{"issue":"5","key":"2026072511263347600_wbag033-B19","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1093\/jnci\/djs528","article-title":"Meta-Analysis of Magnetic Resonance Imaging in Detecting Residual Breast Cancer After Neoadjuvant Therapy","volume":"105","author":"Marinovich","year":"2013","journal-title":"J Natl Cancer Inst."},{"issue":"6","key":"2026072511263347600_wbag033-B20","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1245\/s10434-009-0441-5","article-title":"Residual Breast Cancer Diagnosed by MRI in Patients Receiving Neoadjuvant Chemotherapy with and Without Bevacizumab","volume":"16","author":"Bahri","year":"2009","journal-title":"Ann Surg Oncol."},{"issue":"5","key":"2026072511263347600_wbag033-B21","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.1245\/s10434-018-6413-x","article-title":"Contrast-Enhanced Spectral Mammography is Comparable to MRI in the Assessment of Residual Breast Cancer Following Neoadjuvant Systemic Therapy","volume":"25","author":"Patel","year":"2018","journal-title":"Ann Surg Oncol."},{"issue":"10","key":"2026072511263347600_wbag033-B22","doi-asserted-by":"publisher","first-page":"6207","DOI":"10.1245\/s10434-022-12128-5","article-title":"Accuracy of Posttreatment Imaging for Evaluation of Residual in Breast Disease After Neoadjuvant Endocrine Therapy","volume":"29","author":"Zhang","year":"2022","journal-title":"Ann Surg Oncol."},{"issue":"9","key":"2026072511263347600_wbag033-B23","doi-asserted-by":"publisher","first-page":"2254","DOI":"10.1007\/s00268-019-05032-9","article-title":"MRI Performance in Detecting pCR After Neoadjuvant Chemotherapy by Molecular Subtype of Breast Cancer","volume":"43","author":"Yu","year":"2019","journal-title":"World J Surg."},{"issue":"3","key":"2026072511263347600_wbag033-B24","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1159\/000537874","article-title":"Neoadjuvant Chemotherapy and Pathologic Complete Response in HR+\/HER2\u2212 Breast Cancer: Impact of Tumor Ki67 and ER Status","volume":"69","author":"Akdag","year":"2024","journal-title":"Chemotherapy."},{"issue":"6","key":"2026072511263347600_wbag033-B25","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1111\/tbj.12811","article-title":"Magnetic resonance imaging patterns of tumor regression in breast cancer patients after neo-adjuvant chemotherapy, and an analysis of the influencing factors","volume":"23","author":"Li","year":"2017","journal-title":"Breast J."},{"issue":"1","key":"2026072511263347600_wbag033-B26","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1186\/s40064-016-2419-7","article-title":"Diagnostic accuracy of metastatic axillary lymph nodes in breast MRI","volume":"5","author":"Arslan","year":"2016","journal-title":"Springerplus."},{"issue":"6","key":"2026072511263347600_wbag033-B27","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1007\/s12282-023-01488-9","article-title":"Diagnostic accuracy of pre-operative breast magnetic resonance imaging (MRI) in predicting axillary lymph node metastasis: variations in intrinsic subtypes, and strategy to improve negative predictive value\u2014an analysis of 2473 invasive breast cancer patie","volume":"30","author":"Chen","year":"2023","journal-title":"Breast Cancer."},{"issue":"11","key":"2026072511263347600_wbag033-B28","doi-asserted-by":"publisher","first-page":"3865","DOI":"10.1007\/s00330-016-4235-4","article-title":"Preoperative axillary lymph node evaluation in breast cancer patients by breast magnetic resonance imaging (MRI): Can breast MRI exclude advanced nodal disease?","volume":"26","author":"Hyun","year":"2016","journal-title":"Eur Radiol."},{"issue":"2","key":"2026072511263347600_wbag033-B29","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1148\/radiol.11110639","article-title":"Accuracy of Unenhanced MR Imaging in the Detection of Axillary Lymph Node Metastasis: Study of Reproducibility and Reliability","volume":"262","author":"Scaranelo","year":"2012","journal-title":"Radiology."}],"container-title":["Journal of Breast Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jbi\/advance-article-pdf\/doi\/10.1093\/jbi\/wbag033\/70032045\/wbag033.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbi\/advance-article-pdf\/doi\/10.1093\/jbi\/wbag033\/70032045\/wbag033.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T15:26:39Z","timestamp":1784993199000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbi\/advance-article\/doi\/10.1093\/jbi\/wbag033\/8741882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,25]]},"references-count":29,"URL":"https:\/\/doi.org\/10.1093\/jbi\/wbag033","relation":{},"ISSN":["2631-6110","2631-6129"],"issn-type":[{"value":"2631-6110","type":"print"},{"value":"2631-6129","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,25]]},"article-number":"wbag033"}}