{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T10:35:58Z","timestamp":1787999758533,"version":"build-2784847793"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,1,28]],"date-time":"2024-01-28T00:00:00Z","timestamp":1706400000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Roche pharmaceutical company"},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-07-PHYSIO-023"],"award-info":[{"award-number":["ANR-07-PHYSIO-023"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-10-BLAN-1137"],"award-info":[{"award-number":["ANR-10-BLAN-1137"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006451","name":"Hospices Civils de Lyon","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006451","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Abondement ANVAR","award":["E1482.042"],"award-info":[{"award-number":["E1482.042"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Studies on muscle strength and physical function after fracture are focused on short follow-ups and adjacent anatomical region. We compared loss of muscle strength and physical function in men after fracture with normal ageing-related decline. In 823 men aged 60\u201387, measurements of grip strength and clinical tests (chair stands, balance) were performed every 4\u00a0years for 12\u00a0years. In 155 men with incident fracture, we compared the status after vs. before the fracture. In men without fracture (controls), we compared the status on the first follow-up (4\u00a0years) vs. baseline. In men with fracture, grip strength decreased more than in the controls (41%, 0.28SD, P\u2009&amp;lt;\u2009.01). Men with fracture had higher risk of incident deterioration on the five chair-stand test vs. the controls (OR\u2009=\u20092.45, P\u2009&amp;lt;\u2009.001). They had higher risk of incident inability to stand for 10s with closed eyes vs. the controls (OR\u2009=\u20094.80, P\u2009&amp;lt;\u2009.01). They also had higher risk of deterioration on the tandem walk than the controls: forwards (OR\u2009=\u20092.04, P\u2009&amp;lt;\u2009.01), backwards (OR\u2009=\u20092.25, P\u2009&amp;lt;\u2009.005). The rapid physical decline was not limited to the region of the fracture site. In men who had incident non-upper limb fractures, grip strength decreased more (32%, P\u2009&amp;lt;\u2009.05) vs. the controls. In men who had incident non-lower limb fractures, the risk of decline in the tests of the lower limbs was higher vs. controls (chair stands, OR\u2009=\u20092.73, P\u2009&amp;lt;\u2009.001). The risk of decline was higher in men with clinical fractures which occurred &amp;gt;1\u00a0year before the next visit vs. controls (tandem walk forwards, OR\u2009=\u20092.98, P\u2009&amp;lt;\u2009.005). Overall, in older men, fractures were associated with greater loss of muscle strength and physical function vs. normal ageing. This accelerated decline was also found in the anatomical regions remote from the fracture site. Thus, programs to decrease or reverse the post-fracture decline could have beneficial effects on subsequent fracture risk.<\/jats:p>","DOI":"10.1093\/jbmr\/zjae014","type":"journal-article","created":{"date-parts":[[2024,1,28]],"date-time":"2024-01-28T20:45:51Z","timestamp":1706474751000},"page":"252-259","source":"Crossref","is-referenced-by-count":8,"title":["Decline in muscle strength and physical function after fracture in men \u2013 the prospective STRAMBO study"],"prefix":"10.1093","volume":"39","author":[{"given":"Pawe\u0142","family":"Szulc","sequence":"first","affiliation":[{"name":"INSERM UMR 1033, University of Lyon, Hospices Civils de Lyon, H\u00f4pital Edouard Herriot , 69437 Lyon, Place d\u2019Arsonval , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua R","family":"Lewis","sequence":"additional","affiliation":[{"name":"Institute for Nutrition Research , School of Medical and Health Sciences, , 270 Joondalup Drive, Joondalup, Perth WA 6027 , Australia"},{"name":"Edith Cowan University , School of Medical and Health Sciences, , 270 Joondalup Drive, Joondalup, Perth WA 6027 , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Chapurlat","sequence":"additional","affiliation":[{"name":"INSERM UMR 1033, University of Lyon, Hospices Civils de Lyon, H\u00f4pital Edouard Herriot , 69437 Lyon, Place d\u2019Arsonval , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,1,28]]},"reference":[{"issue":"9021","key":"2024041923052887400_ref1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0140-6736(96)01440-7","article-title":"Fall-related factors and risk of hip fracture: the EPIDOS prospective 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