{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T02:38:39Z","timestamp":1790563119461,"version":"4.1.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Patella fractures are not typically considered osteoporotic fractures. We compared bone mineral density (BMD) and microstructure in elderly women from a multiethnic population-based study in New York City with any history of a patella fracture (n\u2009=\u200927) to those without historical fracture (n\u2009=\u2009384) and those with an adult fragility forearm fracture (n\u2009=\u200928) using dual energy x-ray absorptiometry (DXA) and high resolution peripheral quantitative computed tomography (HR-pQCT). Compared to those without fracture, women with patella fracture had 6.5% lower areal BMD (aBMD) by DXA only at the total hip (p=.007), while women with forearm fracture had lower aBMD at multiple sites and lower trabecular bone score (TBS), adjusted for age, body mass index, race and ethnicity (all p&amp;lt;.05). By HR-pQCT, adjusted radial total and trabecular (Tb) volumetric BMD (vBMD) and Tb number were 10%\u201324% lower while Tb spacing was 12-23% higher (all p&amp;lt;.05) in the fracture groups versus women without fracture. Women with a forearm, but not a patella, fracture also had lower adjusted radial cortical (Ct) area and vBMD and 21.8% (p&amp;lt;.0001) lower stiffness vs. women without fracture. At the tibia, the fracture groups had 9.3%\u201315.7% lower total and Tb vBMD (all p&amp;lt;.05) compared to the non-fracture group. Women with a forearm fracture also had 10.9, and 14.7% lower tibial Ct area and thickness versus those without fracture. Compared to women without fracture, tibial stiffness was 9.9% and 12% lower in the patella and forearm fracture groups, respectively (all p&amp;lt;.05). By HR-pQCT, the patella vs. forearm fracture group had 36% higher radial Tb heterogeneity (p&amp;lt;.05). In summary, women with patella fracture had Tb deterioration by HR-pQCT associated with lower tibial mechanical competence that was similar to those with fragility forearm fracture, a more universally accepted \u201costeoporotic\u201d fracture. These data suggest patella fractures are associated with skeletal fragility and warrant skeletal evaluation.<\/jats:p>","DOI":"10.1093\/jbmr\/zjae165","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T15:26:30Z","timestamp":1728314790000},"page":"1752-1761","source":"Crossref","is-referenced-by-count":6,"title":["Patella fractures are associated with bone fragility \u2013 a retrospective study"],"prefix":"10.1093","volume":"39","author":[{"given":"Isabella","family":"Rosillo","sequence":"first","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Germosen","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4978-0717","authenticated-orcid":false,"given":"Sanchita","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ragyie","family":"Rawal","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivelisse","family":"Colon","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Bucovsky","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayoung","family":"Kil","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Shane","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7205-6527","authenticated-orcid":false,"given":"Marcella","family":"Walker","sequence":"additional","affiliation":[{"name":"Division of Endocrinology , Department of Medicine, , New York, NY 10032 ,","place":["United States"]},{"name":"Columbia University Irving Medical Center , Department of Medicine, , New York, NY 10032 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,10]]},"reference":[{"issue":"2","key":"2024121308332974100_ref1","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S2215-0366(21)00395-3","article-title":"Global, regional, and national burden of bone fractures in 204 countries and territories, 1990-2019: a systematic analysis from the global burden of disease study 2019","volume":"9","author":"Collaborators GBDF","year":"2021","journal-title":"Lancet Healthy Longev"},{"issue":"3","key":"2024121308332974100_ref2","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1002\/jbmr.2072","article-title":"Trends in fracture incidence: a population-based study over 20 years","volume":"29","author":"Amin","year":"2014","journal-title":"J Bone Miner Res"},{"issue":"11","key":"2024121308332974100_ref3","doi-asserted-by":"publisher","first-page":"837","DOI":"10.7326\/0003-4819-115-11-837","article-title":"Which fractures are associated with low appendicular bone mass in elderly women? 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