{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T08:24:04Z","timestamp":1786955044334,"version":"build-2736575974"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,29]]},"DOI":"10.1093\/jbmr\/zjaf204","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T12:22:50Z","timestamp":1767442970000},"page":"590-591","source":"Crossref","is-referenced-by-count":0,"title":["Tuning RUNX2 in craniofacial development and metaphyseal dysplasia with maxillary hypoplasia and brachydactyly (MDMHB)"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9577-3249","authenticated-orcid":false,"given":"Yuki","family":"Matsushita","sequence":"first","affiliation":[{"name":"Department of Skeletal Development and Regenerative Biology, Nagasaki University Graduate School of Biomedical Sciences , Nagasaki 852-8588 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"issue":"5","key":"2026081703264408600_ref1","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/s0092-8674(00)80258-5","article-title":"Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts","volume":"89","author":"Komori","year":"1997","journal-title":"Cell"},{"issue":"5","key":"2026081703264408600_ref2","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/s0092-8674(00)80257-3","article-title":"Osf2\/Cbfa1: a transcriptional activator of osteoblast differentiation","volume":"89","author":"Ducy","year":"1997","journal-title":"Cell"},{"key":"2026081703264408600_ref3","author":"Bikas","year":"2025","journal-title":"J Bone Miner Res"},{"issue":"41","key":"2026081703264408600_ref4","doi-asserted-by":"publisher","first-page":"14665","DOI":"10.1073\/pnas.0504750102","article-title":"Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors","volume":"102","author":"Akiyama","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"2026081703264408600_ref5","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.ajhg.2012.12.001","article-title":"Metaphyseal dysplasia with maxillary hypoplasia and brachydactyly is caused by a duplication in RUNX2","volume":"92","author":"Moffatt","year":"2013","journal-title":"Am J Hum Genet"},{"issue":"6937","key":"2026081703264408600_ref6","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1038\/nature01657","article-title":"Developmental regulation of the growth plate","volume":"423","author":"Kronenberg","year":"2003","journal-title":"Nature"},{"issue":"33","key":"2026081703264408600_ref7","doi-asserted-by":"publisher","first-page":"12097","DOI":"10.1073\/pnas.1302703111","article-title":"Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation","volume":"111","author":"Yang","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"issue":"7730","key":"2026081703264408600_ref8","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1038\/s41586-018-0662-5","article-title":"Resting zone of the growth plate houses a unique class of skeletal stem cells","volume":"563","author":"Mizuhashi","year":"2018","journal-title":"Nature"}],"container-title":["Journal of Bone and Mineral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jbmr\/advance-article-pdf\/doi\/10.1093\/jbmr\/zjaf204\/66281744\/zjaf204.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/41\/6\/590\/66281744\/zjaf204.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/41\/6\/590\/66281744\/zjaf204.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T07:26:48Z","timestamp":1786951608000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbmr\/article\/41\/6\/590\/8415514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,6]]},"references-count":8,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,1,6]]},"published-print":{"date-parts":[[2026,5,29]]}},"URL":"https:\/\/doi.org\/10.1093\/jbmr\/zjaf204","relation":{},"ISSN":["0884-0431","1523-4681"],"issn-type":[{"value":"0884-0431","type":"print"},{"value":"1523-4681","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2026,1,6]]}}}