{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:06:35Z","timestamp":1785416795854,"version":"3.56.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01 HD-095825"],"award-info":[{"award-number":["R01 HD-095825"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Women living with HIV (WLWH) in resource-limited settings have benefited greatly from antiretroviral therapy (ART). However, they have several risk factors that can affect their bone health including being female, high parity\/breastfeeding, use of life-long ART, and HIV disease itself. This study assessed bone mineral density (BMD) among recently pregnant WLWH (WLWH-P), and compared BMD changes over 3\u00a0yr with WLWH who were not pregnant (WLWH-NP) and with recently pregnant HIV-negative women (HIV-neg-P). We co-enrolled 104 WLWH-P from an ongoing cohort study in Malawi and Uganda, and used linear mixed models to compare standardized BMD values over 30-36\u00a0mo with 109 HIV-neg-P women matched for age-group\/parity, and 99 age-group\/parity matched WLWH who did not plan to become pregnant over 36\u00a0mo. BMD was assessed via DXA at baseline, 12, 24, and 30-36\u00a0mo. At baseline, median age of WLWH was 33\u00a0yr with HIV-neg-P being 32\u00a0yr. 91.4% of WLWH-P, and 87.9% of WLWH-NP were on Tenofovir-ART regimens. At baseline, 12, 24, and 30-36\u00a0mo postpartum, WLWH-P had lower mean standardized BMD values for FN, LS, and TH compared to HIV-neg-P women, although differences were not statistically significant except for baseline TH. In conclusion, both groups demonstrated BMD increase to above baseline scores by 30-36\u00a0mo. For WLWH-P compared to WLWH-NP, mean standardized BMD values trended lower between baseline and 24\u00a0mo. Both WLWH-P and HIV-neg-P women showed BMD recovery to baseline for FN, LS, and TH by 30-36\u00a0mo postpartum. However, mean BMD standard-scores trended lower throughout follow-up for WLWH-P compared to HIV-neg-P women. WLWH-P and WLWH-NP women had similar BMD standardized scores by 30-36\u00a0mo. The BMD recovery results are encouraging, but longer follow-up is needed to assess fracture risk among older WLWH compared to HIV-negative women.<\/jats:p>","DOI":"10.1093\/jbmr\/zjag021","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T15:46:06Z","timestamp":1773330366000},"page":"837-847","source":"Crossref","is-referenced-by-count":1,"title":["Recovery in BMD following recent repeat pregnancy and breastfeeding among African women with and without HIV"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0046-4353","authenticated-orcid":false,"given":"Flavia Matovu","family":"Kiweewa","sequence":"first","affiliation":[{"name":"Makerere University-Johns Hopkins University (MU-JHU) Research Collaboration , Kampala, +256 ,","place":["Uganda"]},{"name":"School of Public Health, Makerere University , Kampala, 000256 ,","place":["Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5373-2086","authenticated-orcid":false,"given":"Lara","family":"Lewis","sequence":"additional","affiliation":[{"name":"Centre for AIDS Programme of Research in South Africa , Durban, 4001 ,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynda","family":"Stranix-Chibanda","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences, University of Zimbabwe , Harare, 000263 ,","place":["Zimbabwe"]},{"name":"University of Zimbabwe Clinical Trials Research Centre (UZ-CTRC) , Harare, 000263 ,","place":["Zimbabwe"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sufia","family":"Dadabhai","sequence":"additional","affiliation":[{"name":"The Johns Hopkins Bloomberg School of Public Health , Baltimore, MD 21205 ,","place":["United States"]},{"name":"Johns Hopkins Research Project , Blantyre, 000265 ,","place":["Malawi"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2662-0756","authenticated-orcid":false,"given":"Patience","family":"Atuhaire","sequence":"additional","affiliation":[{"name":"Makerere University-Johns Hopkins University (MU-JHU) Research Collaboration , Kampala, +256 ,","place":["Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felluna","family":"Chauwa","sequence":"additional","affiliation":[{"name":"Johns Hopkins Research Project , Blantyre, 000265 ,","place":["Malawi"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jim","family":"Aizire","sequence":"additional","affiliation":[{"name":"The Johns Hopkins Bloomberg School of Public Health , Baltimore, MD 21205 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taha E","family":"Taha","sequence":"additional","affiliation":[{"name":"The Johns Hopkins Bloomberg School of Public Health , Baltimore, MD 21205 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1155-0334","authenticated-orcid":false,"given":"John M","family":"Pettifor","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, 2050 ,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean S","family":"Brummel","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health , Boston, MA 02115 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8599-278X","authenticated-orcid":false,"given":"Todd T","family":"Brown","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine , Baltimore, MD, 21205 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Glenn","family":"Fowler","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine , Baltimore, MD, 21205 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"2026073008570243500_ref1","doi-asserted-by":"crossref","DOI":"10.18356\/9789210028370","volume-title":"UNAIDS Global AIDS Update 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