{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:59:34Z","timestamp":1790510374942,"version":"4.1.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,24]]},"abstract":"<jats:title>Vignette<\/jats:title>\n                  <jats:p>A case is discussed of a postmenopausal woman started on alendronate treatment based on a low T-score in the total hip (TH). Three years later, her TH score remains below \u22122.5, the target set by the ASBMR task force on goal-directed therapy.1 The important question at this juncture is whether she should change to a different treatment that might result in better improvement in TH bone mineral density (BMD) or if she should continue treatment with alendronate.<\/jats:p>","DOI":"10.1093\/jbmr\/zjag080","type":"journal-article","created":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T11:31:05Z","timestamp":1778412665000},"page":"1056-1059","source":"Crossref","is-referenced-by-count":0,"title":["Goal-directed therapy is not as simple as it seems"],"prefix":"10.1093","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0719-9801","authenticated-orcid":false,"given":"Nelson B","family":"Watts","sequence":"first","affiliation":[{"name":"Mercy Health Osteoporosis and Bone Health Services , Cincinnati OH 45236 ,","place":["United 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