{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:45:36Z","timestamp":1788864336014,"version":"build-2803163510"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T00:00:00Z","timestamp":1737072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"OSCAR"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Chronic hypoparathyroidism is a rare disease associated with an impaired quality of life. Recommendations suggest frequent monitoring of quality of life, but for French-speaking people, only generic scales are available despite the fact that chronic hypoparathyroidism has specific symptoms and impact. The aim of this study was to adapt and validate the French version of Hypoparathyroid Patient Questionnaire 28 (HPQ28), an already validated tool in patients living with chronic hypoparathyroidism, available in English and German. HPQ28 was translated and back-translated from English into French. Translations were harmonized with the original author. Assessment of psychometric properties of the French version of HPQ28 was performed in the ComPaRe-Epi-Hypo e-cohort, a nationwide cohort of adult patients living with chronic hypoparathyroidism in France. Internal consistency was evaluated using Cronbach\u2019s alpha. Dimensional validity was studied using confirmatory factor analysis (CFA). Construct validity compared the answers from the French version of HPQ28 with those from the EQ-5D-5L, EQ-5D-VAS, and MYMPO2 instruments. Reliability was evaluated by the intra-class correlation coefficient (ICC) of a test\u2013retest within a 2-wk interval. Between August 2023 and August 2024, 183 patients completed HPQ28, EQ-5D, and MYMOP2 scales. The majority (92%) of the participants were women, with a median[IQR] age of 52[44;60]. Etiology of the disease was neck surgery and genetic abnormalities in 82% and 8% of cases, respectively. Internal consistency was good (Cronbach\u2019s alpha 0.93, 95% CI 0.91 to 0.94). CFA found a unidimensional structure of the questionnaire. Construct validity showed positive correlation with MYMOP2 (r\u2009=\u20090.64) and negative correlations with EQ-5D VAS (r\u2009=\u2009\u22120.49) and EQ-5D-5L (r\u2009=\u2009\u22120.64) scores, as hypothesized. Reliability was adequate, with an ICC of 0.88 (95% CI 0.84 to 0.91). In conclusion, we adapted and validated HPQ28 for French-speaking patients suffering from chronic hypoparathyroidism. It can therefore now be used for both research and clinical follow-up.<\/jats:p>","DOI":"10.1093\/jbmrpl\/ziaf011","type":"journal-article","created":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T18:27:53Z","timestamp":1737138473000},"source":"Crossref","is-referenced-by-count":6,"title":["Adaptation and validation of the French version of the Hypoparathyroid Patient Questionnaire 28 (HPQ28) in the ComPaRe-Epi-Hypo e-cohort"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4104-702X","authenticated-orcid":false,"given":"Jean-Philippe","family":"Bertocchio","sequence":"first","affiliation":[{"name":"Service Thyro\u00efde\u2014Tumeurs Endocrines, H\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re , F-75013 Paris ,","place":["France"]},{"name":"Centre de Comp\u00e9tence des maladies rares du calcium et du phosphate, Fili\u00e8re Maladies Rares OSCAR, H\u00f4pital de la Piti\u00e9-Salp\u00eatri\u00e8re , F-75013 Paris ,","place":["France"]},{"name":"SKEZI, SKEZIA+, Les Pap\u00e8teries , F-74960 Annecy ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Soyer","sequence":"additional","affiliation":[{"name":"SKEZI, SKEZIA+, Les Pap\u00e8teries , F-74960 Annecy ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Grosset","sequence":"additional","affiliation":[{"name":"Association Hypoparathyro\u00efdisme France , F-74940 Annecy , France; Hypoparathyroidism,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Bessonies","sequence":"additional","affiliation":[{"name":"Association Hypoparathyro\u00efdisme France , F-74940 Annecy , France; Hypoparathyroidism,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christelle","family":"Nidercorn","sequence":"additional","affiliation":[{"name":"Association Hypoparathyro\u00efdisme France , F-74940 Annecy , France; Hypoparathyroidism,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coralie","family":"Sido","sequence":"additional","affiliation":[{"name":"Association Hypoparathyro\u00efdisme France , F-74940 Annecy , France; Hypoparathyroidism,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viet-Thi","family":"Tran","sequence":"additional","affiliation":[{"name":"Centre de Recherche \u00c9pid\u00e9miologie et Statistique Sorbonne Paris Cit\u00e9 (CRESS-UMR1153), H\u00f4pital H\u00f4tel-Dieu , F-75004 Paris ,","place":["France"]},{"name":"Centre d'Epid\u00e9miologie Clinique, H\u00f4pital H\u00f4tel-Dieu , F-75004 Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6285-324X","authenticated-orcid":false,"given":"Leslie","family":"Toko-Kamga","sequence":"additional","affiliation":[{"name":"Centre de Recherche \u00c9pid\u00e9miologie et Statistique Sorbonne Paris Cit\u00e9 (CRESS-UMR1153), H\u00f4pital H\u00f4tel-Dieu , F-75004 Paris ,","place":["France"]},{"name":"Centre d'Epid\u00e9miologie Clinique, H\u00f4pital H\u00f4tel-Dieu , F-75004 Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Pane","sequence":"additional","affiliation":[{"name":"Centre de Recherche \u00c9pid\u00e9miologie et Statistique Sorbonne Paris Cit\u00e9 (CRESS-UMR1153), H\u00f4pital H\u00f4tel-Dieu , F-75004 Paris ,","place":["France"]},{"name":"Centre d'Epid\u00e9miologie Clinique, H\u00f4pital H\u00f4tel-Dieu , F-75004 Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akram","family":"Hecini","sequence":"additional","affiliation":[{"name":"SKEZI, SKEZIA+, Les Pap\u00e8teries , F-74960 Annecy ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heide","family":"Siggelkow","sequence":"additional","affiliation":[{"name":"Center for Endocrinology, Osteology, Rheumatology, Nuklear Medicine and Human Genetics, University Medical Center , D-37075 G\u00f6ttingen ,","place":["Germany"]},{"name":"Department of Trauma Surgery, Orthopedics and Reconstructive Surgery, University Medical Center , D-37075 G\u00f6ttingen ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Houillier","sequence":"additional","affiliation":[{"name":"Service de Physiologie R\u00e9nale et M\u00e9tabolique, H\u00f4pital Europ\u00e9en Georges Pompidou , F-75015 Paris ,","place":["France"]},{"name":"Centre de R\u00e9f\u00e9rence des Maladies Rares du Calcium et du Phosphate, H\u00f4pital Europ\u00e9en Georges Pompidou , F-75015 Paris ,","place":["France"]},{"name":"Centre de Recherche des Cordeliers, INSERM, Sorbonne 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