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Here, we report a case demonstrating significant improvements in bone density and the absence of new fractures after 12 mo of romosozumab (ROMO) treatment following weaning. This report suggests that ROMO could effectively increase bone density and reduce fracture risk in patients with PLO.<\/jats:p>","DOI":"10.1093\/jbmrpl\/ziaf141","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T10:27:34Z","timestamp":1756808854000},"source":"Crossref","is-referenced-by-count":2,"title":["Effective management of pregnancy- and lactation-associated osteoporosis using romosozumab: a clinical case report"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0729-668X","authenticated-orcid":false,"given":"Atsushi","family":"Goshima","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Osaka Rosai Hospital , Sakai 591-8025 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Tsuboi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Osaka Rosai Hospital , Sakai 591-8025 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