{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:05:50Z","timestamp":1787796350351,"version":"build-2784847793"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T00:00:00Z","timestamp":1699747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The Corona Virus Immune Disease-2019 (COVID-19) pandemic has broadly impacted the mental health of individuals worldwide, especially with restrictions including social distancing and quarantining. Persons with IBD are at increased risk of mental health disorders. The aim was to understand how the COVID-19 pandemic affected adults with a chronic health issue, inflammatory bowel disease (IBD), using a population-based sample.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A survey study in Manitoba was conducted during the second COVID-19 wave in autumn 2020. We assessed proportions of health anxiety and perceived stress using validated measures, as well as stressors during the COVID-19 pandemic. We used univariable and multivariable logistic regression analysis to assess predictors of perceived stress and health anxiety.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 1,384 (47.1%) persons responded, with a mean age of 58.0, and 46.9% had Crohn\u2019s disease. Almost three quarters (73.7%) had increased stress, with 37.7% having increased stress about their IBD, and 33.6% worried about their IBD worsening. 46.0% felt increased stress about accessing their doctor or nurse, and 56.5% felt they had good access to their gastroenterologist. Elevated stress and health anxiety were seen in 63.5% and 17.2% of respondents, respectively. Younger age and being on immune-modifying therapy (IMT) was predictive of increased health anxiety and stress. Longer IBD duration was associated with decreased stress, including those on IMT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Persons with IBD reported high rates of stress and health anxiety early in the COVID-19 pandemic, especially among those on IMT. It will be important to determine how this evolved over time and to what extent this impacted on disease course.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jcag\/gwad047","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T11:04:07Z","timestamp":1699873447000},"page":"244-254","source":"Crossref","is-referenced-by-count":1,"title":["The Impact of COVID-19 on Health Anxiety and Perceived Stress Among Persons with IBD: A Population-representative Study"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9872-6832","authenticated-orcid":false,"given":"Seth R","family":"Shaffer","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , C4-820 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"},{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gia L","family":"Jackson","sequence":"additional","affiliation":[{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney","family":"Chochinov","sequence":"additional","affiliation":[{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casandra","family":"Dolovich","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , C4-820 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"},{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley A","family":"Graff","sequence":"additional","affiliation":[{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"},{"name":"Department of Clinical Health Psychology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , PZ-350 820 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9e","family":"El-Gabalawy","sequence":"additional","affiliation":[{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"},{"name":"Department of Clinical Health Psychology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , PZ-350 820 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souradet","family":"Yuh-Nan Shaw","sequence":"additional","affiliation":[{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9354-2356","authenticated-orcid":false,"given":"Harminder","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , C4-820 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"},{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8041-3574","authenticated-orcid":false,"given":"Charles N","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , C4-820 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"},{"name":"University of Manitoba IBD Clinical and Research Centre, University of Manitoba , MS-783 Sherbrook St Winnipeg, Manitoba, R3A1R9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,12]]},"reference":[{"key":"2023121523054180000_CIT0001","first-page":"e100213","article-title":"\u201cA Nationwide Survey of Psychological Distress among Chinese People in the COVID-19 Epidemic: Implications and Policy Recommendations.\u201d","volume-title":"General Psychiatry","author":"Qiu","year":"2020"},{"key":"2023121523054180000_CIT0002","first-page":"634","article-title":"\u201c\u201cWe Are at Risk Too\u201d: The Disparate Mental Health Impacts of the Pandemic on Younger Generations: Nous Sommes Aussi \u00e0 Risque: Les Effets Disparates de la Pand\u00e9mie Sur la Sant\u00e9 Mentale des G\u00e9n\u00e9rations Plus Jeunes.\u201d","volume-title":"Canadian Journal of Psychiatry","author":"El-Gabalawy","year":"2021"},{"key":"2023121523054180000_CIT0003","first-page":"1405","article-title":"\u201cImpact of COVID-19 on Healthcare Resource Utilization among Patients with Inflammatory Bowel Disease in the USA.\u201d","volume-title":"Journal of Crohn\u2019s and Colitis","author":"Ungaro","year":"2022"},{"key":"2023121523054180000_CIT0004","first-page":"1989","article-title":"\u201cThe Manitoba IBD Cohort Study: A Population-based Study of the Prevalence of Lifetime and 12-Month Anxiety and Mood Disorders.\u201d","volume-title":"American Journal of Gastroenterology","author":"Walker","year":"2008"},{"key":"2023121523054180000_CIT0005","first-page":"17","article-title":"\u201cIncreased Incidence of Psychiatric Disorders in Immune-mediated Inflammatory Disease.\u201d","volume-title":"Journal of Psychosomatic Research","author":"Marrie","year":"2017"},{"key":"2023121523054180000_CIT0006","first-page":"360","article-title":"\u201cIncreased Burden of Psychiatric Disorders in Inflammatory Bowel Disease.\u201d","volume-title":"Inflammatory Bowel Diseases","author":"Bernstein","year":"2019"},{"key":"2023121523054180000_CIT0007","first-page":"1994","article-title":"\u201cA Prospective Population-based Study of Triggers of Symptomatic Flares in IBD.\u201d","volume-title":"American Journal of Gastroenterology","author":"Bernstein","year":"2010"},{"key":"2023121523054180000_CIT0008","first-page":"473","article-title":"\u201cEvidence of Bidirectional Associations Between Perceived Stress and Symptom Activity: A Prospective Longitudinal Investigation in Inflammatory Bowel Disease.\u201d","volume-title":"Inflammatory Bowel Diseases","author":"Sexton","year":"2017"},{"key":"2023121523054180000_CIT0009","first-page":"e000581","article-title":"\u201cDepression, Anxiety and Stress among Patients with Inflammatory Bowel Disease During the COVID-19 Pandemic: Australian National Survey.\u201d","volume-title":"BMJ Open Gastroenterol","author":"Cheema","year":"2021"},{"key":"2023121523054180000_CIT0010","first-page":"2876","article-title":"\u201cCOVID-19 Pandemic Increased Anxiety Among Patients with Inflammatory Bowel Disease: A Patient Survey in a Tertiary Referral Center.\u201d","volume-title":"Digestive Diseases and Sciences","author":"Stone","year":"2022"},{"key":"2023121523054180000_CIT0011","first-page":"3274","article-title":"\u201cPerianal Crohn\u2019s Disease and Pregnancy: Role of the Mode of Delivery.\u201d","volume-title":"American Journal of Gastroenterology","author":"Ilnyckyji","year":"1999"},{"key":"2023121523054180000_CIT0012","first-page":"993","article-title":"\u201cA Population-Based Case Control Study of Potential Risk Factors for IBD.\u201d","volume-title":"American Journal of Gastroenterology","author":"Bernstein","year":"2006"},{"key":"2023121523054180000_CIT0013","article-title":"\u201cInternet, Phone, Mail, and Mixed-Mode Surveys: The Tailored Design Method.\u201d","author":"Dillman","year":"2014","journal-title":"Wiley"},{"issue":"4","key":"2023121523054180000_CIT0014","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2307\/2136404","article-title":"\u201cA Global Measure of Perceived Stress.\u201d","volume":"24","author":"Cohen","year":"1983","journal-title":"Journal of Health and Social Behavior"},{"key":"2023121523054180000_CIT0015","first-page":"843","article-title":"\u201cThe Health Anxiety Inventory: Development and Validation of Scales for the Measurement of Health Anxiety and Hypochondriasis.\u201d","volume-title":"Psychological Medicine","author":"Salkovskis","year":"2002"},{"key":"2023121523054180000_CIT0016","first-page":"1461","article-title":"\u201cHealth Care Services in IBD: Factors Associated with Service Utilization and Preferences for Service Options for Routine and Urgent Care.\u201d","volume-title":"Inflammatory Bowel Diseases","author":"Bernstein","year":"09 2017"},{"key":"2023121523054180000_CIT0017","first-page":"1681507","article-title":"\u201cAssessing the Relationship between Sources of Stress and Symptom Changes among Persons with IBD over Time: A Prospective Study.\u201d","volume-title":"Canadian Journal of Gastroenterology and Hepatology","author":"Bernstein","year":"2016"},{"key":"2023121523054180000_CIT0018","first-page":"5540786","article-title":"\u201cDepression and Anxiety Disorders Impact in the Quality of Life of Patients with Inflammatory Bowel Disease.\u201d","volume-title":"Psychiatry Journal","author":"Yamamoto-Furusho","year":"2021"},{"key":"2023121523054180000_CIT0019","first-page":"113","article-title":"\u201cRisk Factors for Depression in the Elderly Inflammatory Bowel Disease Population.\u201d","volume-title":"Journal of Crohn\u2019s and Colitis","author":"Long","year":"2014"},{"key":"2023121523054180000_CIT0020","first-page":"101205","article-title":"\u201cAging in COVID-19: Vulnerability, Immunity and Intervention.\u201d","volume-title":"Ageing Research Reviews","author":"Chen","year":"2021"},{"key":"2023121523054180000_CIT0021","first-page":"855","article-title":"\u201cMortality-related Risk Factors of COVID-19: A Systematic Review and Meta-analysis of 42 Studies and 423,117 Patients.\u201d","volume-title":"BMC Infectious Diseases","author":"Dessie","year":"2021"},{"key":"2023121523054180000_CIT0022","first-page":"545","article-title":"\u201cPatients with Inflammatory Bowel Disease on Immunosuppressive Drugs: Perspectives\u2019 on COVID-19 and Health Care Service During the Pandemic.\u201d","volume-title":"Scandinavian Journal of Gastroenterology","author":"Moum","year":"2021"},{"key":"2023121523054180000_CIT0023","first-page":"74","article-title":"\u201cPrevalence of Psychiatric Disorders in U.S. Older Adults: Findings from a Nationally Representative Survey.\u201d","volume-title":"World Psychiatry","author":"Reynolds","year":"2015"},{"key":"2023121523054180000_CIT0024","first-page":"791","article-title":"\u201cHigh Levels of Psychological Resilience Associated With Less Disease Activity, Better Quality of Life, and Fewer Surgeries in Inflammatory Bowel Disease.\u201d","volume-title":"Inflammatory Bowel Diseases","author":"Sehgal","year":"2021"},{"key":"2023121523054180000_CIT0025","first-page":"888","article-title":"\u201cHigh Levels of Psychological Resilience Are Associated With Decreased Anxiety in Inflammatory Bowel Disease.\u201d","volume-title":"Inflammatory Bowel Diseases","author":"Philippou","year":"2022"},{"key":"2023121523054180000_CIT0026","first-page":"526","article-title":"\u201cPopulation-based Controlled Study of Social Support, Self-perceived Stress, Activity and Work Issues, and Access to Health Care in Inflammatory Bowel Disease.\u201d","volume-title":"Inflammatory Bowel Diseases","author":"Rogala","year":"2008"},{"key":"2023121523054180000_CIT0027","first-page":"271","article-title":"\u201cCOVID-19 in IBD: The Experience of a Single Tertiary IBD Center.\u201d","volume-title":"Digestive and Liver Disease","author":"Rizzello","year":"2021"},{"key":"2023121523054180000_CIT0028","first-page":"222","article-title":"\u201cImpact of the COVID-19 Pandemic on Inflammatory Bowel Disease: The Role of Emotional Stress and Social Isolation.\u201d","volume-title":"Stress and Health","author":"Nass","year":"2022"},{"key":"2023121523054180000_CIT0029","first-page":"1001","article-title":"\u201cThe Relationship Among Perceived Stress, Symptoms, and Inflammation in Persons With Inflammatory Bowel Disease.\u201d","volume-title":"American Journal of Gastroenterology","author":"Targownik","year":"2015"},{"key":"2023121523054180000_CIT0030","first-page":"510","article-title":"\u201cMental Health and the COVID-19 Pandemic.\u201d","volume-title":"New England Journal of Medicine","author":"Pfefferbaum","year":"2020"},{"key":"2023121523054180000_CIT0031","first-page":"113631","article-title":"\u201cAssociations Between Periods of COVID-19 Quarantine and Mental Health in Canada.\u201d","volume-title":"Psychiatry Research","author":"Daly","year":"2021"},{"key":"2023121523054180000_CIT0032","first-page":"55","article-title":"\u201cImpact of COVID-19 Pandemic on Mental Health in the General Population: A Systematic Review.\u201d","volume-title":"Journal of Affective Disorders","author":"Xiong","year":"2020"}],"container-title":["Journal of the Canadian Association of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcag\/article-pdf\/6\/6\/244\/54492728\/gwad047.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcag\/article-pdf\/6\/6\/244\/54492728\/gwad047.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T23:06:56Z","timestamp":1702681616000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcag\/article\/6\/6\/244\/7416422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,12]]},"references-count":32,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,11,12]]},"published-print":{"date-parts":[[2023,12,15]]}},"URL":"https:\/\/doi.org\/10.1093\/jcag\/gwad047","relation":{},"ISSN":["2515-2084","2515-2092"],"issn-type":[{"value":"2515-2084","type":"print"},{"value":"2515-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,12,1]]},"published":{"date-parts":[[2023,11,12]]}}}