{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:05:52Z","timestamp":1787241952833,"version":"build-2736575974"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"Supplement_2","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Inflammatory bowel diseases (IBD), including Crohn\u2019s disease (CD) and ulcerative colitis (UC), result from a loss of immune tolerance to gut microbiota, leading to inflammation. Their incidence is increasing, especially in newly industrialized countries. The etiology is multifactorial, involving genetic, immune, microbiota, and environmental factors. Maternal microbiome changes during pregnancy can elevate IBD risk in offspring, influenced by diet, smoking, and antibiotic exposure. Early life microbiota manipulation shows promise for preventing IBD. Epidemiological and pre-clinical studies highlight diet\u2019s significant role in IBD development. High-inflammatory dietary patterns correlate with increased CD risk, while Mediterranean-like diets promote beneficial gut microbiome changes and reduce inflammation. Certain food additives, such as emulsifiers and artificial sweeteners, may exacerbate IBD by altering gut microbiota. A systematic review indicates that higher ultra-processed food consumption significantly increases CD risk. Lifestyle modifications, including healthy dietary adherence, could substantially reduce IBD risk, with studies showing that favorable choices can halve the risk in genetically predisposed individuals. Additionally, maternal diet impacts offspring IBD risk, as seen in mouse models where high-fat diets led to increased inflammation. Evidence suggests that maternal probiotics and specific dietary patterns may mitigate these risks. Overall, these findings emphasize the potential for dietary interventions to modulate gut microbiota and immune responses, offering promising avenues for IBD prevention and management. Further large-scale studies are needed to explore the impact of dietary strategies on IBD risk and gut health.<\/jats:p>","DOI":"10.1093\/jcag\/gwae039","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T07:15:46Z","timestamp":1737443746000},"page":"S44-S50","source":"Crossref","is-referenced-by-count":11,"title":["Early life factors, diet and microbiome, and risk of inflammatory bowel disease"],"prefix":"10.1093","volume":"8","author":[{"given":"Joyce Wing Yan","family":"Mak","sequence":"first","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong , Shatin ,","place":["Hong Kong"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron Tsz Wang","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong , Shatin ,","place":["Hong Kong"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6850-4454","authenticated-orcid":false,"given":"Siew Chien","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong , Shatin ,","place":["Hong Kong"]},{"name":"Microbiota I-Center (MagIC) , Shatin ,","place":["Hong Kong"]},{"name":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong , Shatin ,","place":["Hong Kong"]},{"name":"State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong , Shatin ,","place":["Hong Kong"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"issue":"10114","key":"2025022107392316600_CIT0001","doi-asserted-by":"publisher","first-page":"2769","DOI":"10.1016\/S0140-6736(17)32448-0","article-title":"Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies","volume":"390","author":"Ng","year":"2017","journal-title":"Lancet."},{"issue":"7907","key":"2025022107392316600_CIT0002","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1038\/s41586-022-04567-7","article-title":"Environmental factors shaping the gut microbiome in a Dutch population","volume":"604","author":"Gacesa","year":"2022","journal-title":"Nature."},{"issue":"3","key":"2025022107392316600_CIT0003","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1053\/j.gastro.2021.05.054","article-title":"Early-life microbial restitution reduces colitis risk promoted by antibiotic-induced gut dysbiosis in interleukin 10\u2212\/\u2212 mice","volume":"161","author":"Miyoshi","year":"2021","journal-title":"Gastroenterology."},{"issue":"2","key":"2025022107392316600_CIT0004","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.cell.2020.08.047","article-title":"Maternal fecal microbiota transplantation in cesarean-born infants rapidly restores normal gut microbial development: a proof-of-concept study","volume":"183","author":"Korpela","year":"2020","journal-title":"Cell."},{"issue":"3","key":"2025022107392316600_CIT0005","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.resmic.2007.12.007","article-title":"Is meconium from healthy newborns actually sterile","volume":"159","author":"Jim\u00e9nez","year":"2008","journal-title":"Res Microbiol."},{"issue":"6","key":"2025022107392316600_CIT0006","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1086\/513669","article-title":"Broad-spectrum bacterial rDNA polymerase chain reaction assay for detecting amniotic fluid infection among women in premature labor","volume":"24","author":"Hitti","year":"1997","journal-title":"Clin Infect Dis."},{"issue":"3","key":"2025022107392316600_CIT0007","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1515\/jpm.2010.040","article-title":"Detection of urea plasmas by the polymerase chain reaction in the amniotic fluid of patients with cervical insufficiency","volume":"38","author":"Oh","year":"2010","journal-title":"J Perinat Med."},{"issue":"4","key":"2025022107392316600_CIT0008","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1007\/s00284-005-0020-3","article-title":"Isolation of commensal bacteria from umbilical cord blood of healthy neonates born by cesarean section","volume":"51","author":"Jim\u00e9nez","year":"2005","journal-title":"Curr Microbiol."},{"issue":"1","key":"2025022107392316600_CIT0009","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/j.1472-765X.2008.02475.x","article-title":"Bifidobacterium and Lactobacillus DNA in the human placenta","volume":"48","author":"Satokari","year":"2009","journal-title":"Lett Appl Microbiol."},{"issue":"3","key":"2025022107392316600_CIT0010","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1203\/01.PDR.0000153869.96337.90","article-title":"Bacteria and inflammatory cells in fetal membranes do not always cause preterm labor","volume":"57","author":"Steel","year":"2005","journal-title":"Pediatr Res."},{"issue":"9356","key":"2025022107392316600_CIT0011","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/S0140-6736(03)12489-0","article-title":"Gut flora in health and disease","volume":"361","author":"Guarner","year":"2003","journal-title":"Lancet."},{"issue":"4","key":"2025022107392316600_CIT0012","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.chom.2016.03.012","article-title":"Another reason to thank mom: gestational effects of microbiota metabolites","volume":"19","author":"Rakoff-Nahoum","year":"2016","journal-title":"Cell Host Microbe."},{"issue":"6279","key":"2025022107392316600_CIT0013","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1126\/science.aad2571","article-title":"The maternal microbiota drives early postnatal innate immune development","volume":"351","author":"Gomez de Ag\u00fcero","year":"2016","journal-title":"Science."},{"issue":"1","key":"2025022107392316600_CIT0014","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1038\/s41575-023-00864-2","article-title":"The maternal gut microbiome in pregnancy: implications for the developing immune system","volume":"21","author":"Koren","year":"2024","journal-title":"Nat Rev Gastroenterol Hepatol."},{"issue":"3","key":"2025022107392316600_CIT0015","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/j.cell.2012.07.008","article-title":"Host remodeling of the gut microbiome and metabolic changes during pregnancy","volume":"150","author":"Koren","year":"2012","journal-title":"Cell."},{"issue":"1","key":"2025022107392316600_CIT0016","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1136\/gutjnl-2018-317855","article-title":"Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice","volume":"69","author":"Torres","year":"2020","journal-title":"Gut."},{"issue":"2","key":"2025022107392316600_CIT0017","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1038\/s41564-017-0075-5","article-title":"Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice","volume":"3","author":"Schulfer","year":"2018","journal-title":"Nat Microbiol."},{"issue":"2","key":"2025022107392316600_CIT0018","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1096\/fba.2021-00078","article-title":"Maternal Lactobacillus reuteri supplementation shifts the intestinal microbiome in mice and provides protection from experimental colitis in female offspring","volume":"4","author":"Krishna","year":"2022","journal-title":"FASEB Bioadv"},{"key":"2025022107392316600_CIT0019","doi-asserted-by":"publisher","first-page":"100573","DOI":"10.1016\/j.conctc.2020.100573","article-title":"A dietary intervention to improve the microbiome composition of pregnant women with Crohn\u2019s disease and their offspring: the MELODY (Modulating Early Life Microbiome through Dietary Intervention in Pregnancy) trial design","volume":"18","author":"Peter","year":"2020","journal-title":"Contemp Clin Trials Commun"},{"key":"2025022107392316600_CIT0020","doi-asserted-by":"publisher","first-page":"100884","DOI":"10.1016\/j.eclinm.2021.100884","article-title":"Early life exposures and the risk of inflammatory bowel disease: systematic review and meta-analyses","volume":"36","author":"Agrawal","year":"2021","journal-title":"EClinicalMedicine"},{"key":"2025022107392316600_CIT0021","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.reprotox.2021.05.005","article-title":"Maternal prenatal smoking and long-term gastrointestinal morbidity of the offspring: a population-based cohort analysis","volume":"103","author":"Karur","year":"2021","journal-title":"Reprod Toxicol."},{"issue":"2","key":"2025022107392316600_CIT0022","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.celrep.2017.06.060","article-title":"Peripartum antibiotics promote gut dysbiosis, loss of immune tolerance, and Inflammatory Bowel Disease in genetically prone offspring","volume":"20","author":"Miyoshi","year":"2017","journal-title":"Cell Rep"},{"issue":"11","key":"2025022107392316600_CIT0023","doi-asserted-by":"publisher","first-page":"e0142536","DOI":"10.1371\/journal.pone.0142536","article-title":"Antepartum antibiotic treatment increases offspring susceptibility to experimental colitis: a role of the gut microbiota","volume":"10","author":"Munyaka","year":"2015","journal-title":"PLoS One."},{"issue":"3","key":"2025022107392316600_CIT0024","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1093\/nutrit\/nuw061","article-title":"Early-life origin of intestinal inflammatory disorders","volume":"75","author":"Ley","year":"2017","journal-title":"Nutr Rev."},{"issue":"2","key":"2025022107392316600_CIT0025","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1136\/gutjnl-2017-314352","article-title":"Fetal and early life antibiotics exposure and very early onset inflammatory bowel disease: a population-based study","volume":"68","author":"\u00d6rtqvist","year":"2019","journal-title":"Gut."},{"issue":"4","key":"2025022107392316600_CIT0026","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1136\/gutjnl-2022-327724","article-title":"Maternal antibiotic exposure during pregnancy and risk of IBD in offspring: a population-based cohort study","volume":"72","author":"Agrawal","year":"2023","journal-title":"Gut."},{"issue":"1","key":"2025022107392316600_CIT0027","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1093\/ecco-jcc\/jjac111","article-title":"Risk factors for developing Inflammatory Bowel Disease within and across families with a family history of IBD","volume":"17","author":"Torres","year":"2023","journal-title":"J Crohns Colitis."},{"issue":"3","key":"2025022107392316600_CIT0028","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1053\/j.gastro.2020.05.011","article-title":"Dietary inflammatory potential and risk of Crohn\u2019s Disease and ulcerative colitis","volume":"159","author":"Lo","year":"2020","journal-title":"Gastroenterology."},{"issue":"3","key":"2025022107392316600_CIT0029","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1053\/j.gastro.2022.05.037","article-title":"Mediterranean-like dietary pattern associations with gut microbiome composition and subclinical gastrointestinal inflammation","volume":"163","author":"Turpin","year":"2022","journal-title":"Gastroenterology."},{"issue":"7541","key":"2025022107392316600_CIT0030","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/nature14232","article-title":"Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome","volume":"519","author":"Chassaing","year":"2015","journal-title":"Nature."},{"issue":"7521","key":"2025022107392316600_CIT0031","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1038\/nature13793","article-title":"Artificial sweeteners induce glucose intolerance by altering the gut microbiota","volume":"514","author":"Suez","year":"2014","journal-title":"Nature."},{"issue":"2","key":"2025022107392316600_CIT0032","doi-asserted-by":"publisher","first-page":"367","DOI":"10.3390\/molecules23020367","article-title":"Effects of the artificial sweetener neotame on the gut microbiome and fecal metabolites in mice","volume":"23","author":"Chi","year":"2018","journal-title":"Molecules."},{"issue":"7","key":"2025022107392316600_CIT0033","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1136\/gutjnl-2015-310297","article-title":"Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome","volume":"66","author":"Ruiz","year":"2017","journal-title":"Gut."},{"issue":"3","key":"2025022107392316600_CIT0034","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1038\/mi.2013.78","article-title":"Aluminum enhances inflammation and decreases mucosal healing in experimental colitis in mice","volume":"7","author":"Pineton de Chambrun","year":"2014","journal-title":"Mucosal Immunol"},{"issue":"10","key":"2025022107392316600_CIT0035","doi-asserted-by":"publisher","first-page":"2483","DOI":"10.1016\/j.cgh.2023.01.012","article-title":"Food processing and risk of Inflammatory Bowel Disease: a systematic review and meta-analysis","volume":"21","author":"Narula","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"6","key":"2025022107392316600_CIT0036","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1136\/gutjnl-2022-328174","article-title":"Lifestyle factors for the prevention of inflammatory bowel disease","volume":"72","author":"Lopes","year":"2023","journal-title":"Gut."},{"issue":"3","key":"2025022107392316600_CIT0037","doi-asserted-by":"publisher","first-page":"511","DOI":"10.14309\/ajg.0000000000002180","article-title":"The contribution of genetic risk and lifestyle factors in the development of adult-onset Inflammatory Bowel Disease: a prospective cohort study","volume":"118","author":"Sun","year":"2023","journal-title":"Am J Gastroenterol."},{"issue":"16","key":"2025022107392316600_CIT0038","doi-asserted-by":"publisher","first-page":"4137","DOI":"10.1016\/j.cell.2021.06.019","article-title":"Gut-microbiota-targeted diets modulate human immune status","volume":"184","author":"Wastyk","year":"2021","journal-title":"Cell."},{"issue":"12","key":"2025022107392316600_CIT0039","doi-asserted-by":"publisher","first-page":"3475","DOI":"10.1007\/s10620-013-2844-1","article-title":"Dietary red meat aggravates dextran sulfate sodium-induced colitis in mice whereas resistant starch attenuates inflammation","volume":"58","author":"Le Leu","year":"2013","journal-title":"Dig Dis Sci."},{"issue":"7405","key":"2025022107392316600_CIT0040","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1038\/nature11225","article-title":"Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-\/- mice","volume":"487","author":"Devkota","year":"2012","journal-title":"Nature."},{"issue":"5","key":"2025022107392316600_CIT0041","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1136\/gutjnl-2013-305304","article-title":"Long-term intake of dietary fat and risk of ulcerative colitis and Crohn\u2019s disease","volume":"63","author":"Ananthakrishnan","year":"2014","journal-title":"Gut."},{"issue":"10","key":"2025022107392316600_CIT0042","doi-asserted-by":"publisher","first-page":"2195","DOI":"10.1038\/ajg.2010.192","article-title":"Animal protein intake and risk of inflammatory bowel disease: the E3N prospective study","volume":"105","author":"Jantchou","year":"2010","journal-title":"Am J Gastroenterol."},{"issue":"8","key":"2025022107392316600_CIT0043","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1093\/ecco-jcc\/jjac054","article-title":"Meat intake is associated with a higher risk of ulcerative colitis in a large european prospective cohort study\u00f8","volume":"16","author":"Dong","year":"2022","journal-title":"J Crohns Colitis."},{"issue":"1","key":"2025022107392316600_CIT0044","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1093\/advances\/nmab086","article-title":"Effects of dietary patterns on biomarkers of inflammation and immune responses: a systematic review and meta-analysis of randomized controlled trials","volume":"13","author":"Koelman","year":"2022","journal-title":"Adv Nutr."},{"issue":"9","key":"2025022107392316600_CIT0045","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1136\/gutjnl-2019-319505","article-title":"Adherence to a Mediterranean diet is associated with a lower risk of later-onset Crohn\u2019s disease: results from two large prospective cohort studies","volume":"69","author":"Khalili","year":"2020","journal-title":"Gut."},{"key":"2025022107392316600_CIT0046","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/17562848231184056","article-title":"Effects of Crohn\u2019s disease exclusion diet on remission: a systematic review","volume":"16","author":"Zhu","year":"2023","journal-title":"Therap Adv Gastroenterol."},{"issue":"1","key":"2025022107392316600_CIT0047","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/S2468-1253(21)00299-5","article-title":"The Crohn\u2019s disease exclusion diet for induction and maintenance of remission in adults with mild-to-moderate Crohn\u2019s disease (CDED-AD): an open-label, pilot, randomised trial","volume":"7","author":"Yanai","year":"2022","journal-title":"Lancet Gastroenterol Hepatol."},{"issue":"Supplement_1","key":"2025022107392316600_CIT0048","doi-asserted-by":"publisher","first-page":"i1915","DOI":"10.1093\/ecco-jcc\/jjad212.1196","article-title":"P1066 The real-life use of the Crohn\u2019s disease exclusion diet (CDED) in adults with mild-to-moderate Crohn\u2019s disease activity: an interim analysis of an open-label randomized controlled trial","volume":"18","author":"Bodini","year":"2024","journal-title":"J Crohns Colitis."},{"key":"2025022107392316600_CIT0049","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1475-2891-13-5","article-title":"An anti-inflammatory diet as treatment for inflammatory bowel disease: a case series report","volume":"13","author":"Olendzki","year":"2014","journal-title":"Nutr J."},{"issue":"11","key":"2025022107392316600_CIT0050","doi-asserted-by":"publisher","first-page":"2054","DOI":"10.1097\/MIB.0000000000001221","article-title":"Efficacy of the autoimmune protocol diet for Inflammatory Bowel Disease","volume":"23","author":"Konijeti","year":"2017","journal-title":"Inflamm Bowel Dis."},{"issue":"3","key":"2025022107392316600_CIT0051","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/crocol\/otz019","article-title":"An autoimmune protocol diet improves patient-reported quality of life in Inflammatory Bowel Disease","volume":"1","author":"Chandrasekaran","year":"2019","journal-title":"Crohns Colitis"},{"issue":"5","key":"2025022107392316600_CIT0052","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1053\/j.gastro.2018.12.002","article-title":"Treatment of active Crohn\u2019s Disease with an ordinary food-based diet that replicates exclusive enteral nutrition","volume":"156","author":"Svolos","year":"2019","journal-title":"Gastroenterology."},{"issue":"Supplement_1","key":"2025022107392316600_CIT0053","doi-asserted-by":"publisher","first-page":"i112","DOI":"10.1093\/ecco-jcc\/jjab232.107","article-title":"DOP68 CD-TREAT diet induces remission and improves quality of life in an open label trial in children and adults with active Crohn\u2019s Disease","volume":"16","author":"Svolos","year":"2022","journal-title":"J Crohns Colitis."},{"issue":"3","key":"2025022107392316600_CIT0054","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1038\/mi.2010.74","article-title":"An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity","volume":"4","author":"Eri","year":"2011","journal-title":"Mucosal Immunol"},{"key":"2025022107392316600_CIT0055","doi-asserted-by":"publisher","first-page":"622327","DOI":"10.3389\/fcimb.2021.622327","article-title":"Polyphenol enriched diet administration during pregnancy and lactation prevents dysbiosis in ulcerative colitis predisposed littermates","volume":"11","author":"De Santis","year":"2021","journal-title":"Front Cell Infect Microbiol."},{"issue":"1","key":"2025022107392316600_CIT0056","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1186\/s40168-023-01546-6","article-title":"Maternal Western diet mediates susceptibility of offspring to Crohn\u2019s-like colitis by deoxycholate generation","volume":"11","author":"Huang","year":"2023","journal-title":"Microbiome"},{"issue":"9","key":"2025022107392316600_CIT0057","doi-asserted-by":"publisher","first-page":"2016","DOI":"10.1097\/MIB.0000000000000465","article-title":"Maternal high-fat diet accelerates development of Crohn\u2019s disease-like Ileitis in TNF\u0394ARE\/WT offspring","volume":"21","author":"Gruber","year":"2015","journal-title":"Inflamm Bowel Dis."},{"key":"2025022107392316600_CIT0058","doi-asserted-by":"publisher","first-page":"2608","DOI":"10.3389\/fimmu.2018.02608","article-title":"Maternal high fat diet alters gut microbiota of offspring and exacerbates DSS-induced colitis in adulthood","volume":"9","author":"Xie","year":"2018","journal-title":"Front Immunol."},{"issue":"19","key":"2025022107392316600_CIT0059","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.99223","article-title":"Maternal high-fat diet results in microbiota-dependent expansion of ILC3s in mice offspring","volume":"3","author":"Babu","year":"2018","journal-title":"JCI Insight."},{"issue":"2","key":"2025022107392316600_CIT0060","doi-asserted-by":"publisher","first-page":"e1002507","DOI":"10.1371\/journal.pmed.1002507","article-title":"Diet during pregnancy and infancy and risk of allergic or autoimmune disease: a systematic review and meta-analysis","volume":"15","author":"Garcia-Larsen","year":"2018","journal-title":"PLoS Med."},{"issue":"6","key":"2025022107392316600_CIT0061","doi-asserted-by":"publisher","first-page":"S","DOI":"10.1016\/s0016-5085(23)01470-1","article-title":"962 Early life exposure to parental Crohn\u2019s Disease is associated with altered gut microbiome composition, impaired gut permeability, and increased risk of incident crohn\u2019s disease","volume":"164","author":"Lee","year":"2023","journal-title":"Gastroenterology."},{"issue":"8","key":"2025022107392316600_CIT0062","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.3109\/00365528708991950","article-title":"Childhood factors in ulcerative colitis and Crohn\u2019s disease. An international cooperative study","volume":"22","author":"Gilat","year":"1987","journal-title":"Scand J Gastroenterol."},{"issue":"1","key":"2025022107392316600_CIT0063","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1093\/ibd\/izx006","article-title":"Dietary patterns in women with Inflammatory Bowel Disease and risk of adverse pregnancy outcomes: results from The Norwegian Mother and Child Cohort Study (MoBa)","volume":"24","author":"Myklebust-Hansen","year":"2017","journal-title":"Inflamm Bowel Dis."},{"issue":"1","key":"2025022107392316600_CIT0064","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/s12876-020-1182-y","article-title":"Intake of dairy protein during pregnancy in IBD and risk of SGA in a Norwegian population-based mother and child cohort","volume":"20","author":"Bengtson","year":"2020","journal-title":"BMC Gastroenterol."},{"issue":"3","key":"2025022107392316600_CIT0065","doi-asserted-by":"publisher","first-page":"e724","DOI":"10.1542\/peds.2006-1649","article-title":"Bacterial imprinting of the neonatal immune system: lessons from maternal cells","volume":"119","author":"Perez","year":"2007","journal-title":"Pediatrics."}],"container-title":["Journal of the Canadian Association of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jcag\/article-pdf\/8\/Supplement_2\/S44\/62039308\/gwae039.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jcag\/article-pdf\/8\/Supplement_2\/S44\/62039308\/gwae039.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:39:58Z","timestamp":1740105598000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jcag\/article\/8\/Supplement_2\/S44\/8029106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,21]]},"references-count":65,"journal-issue":{"issue":"Supplement_2","published-print":{"date-parts":[[2025,2,21]]}},"URL":"https:\/\/doi.org\/10.1093\/jcag\/gwae039","relation":{},"ISSN":["2515-2084","2515-2092"],"issn-type":[{"value":"2515-2084","type":"print"},{"value":"2515-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,3]]},"published":{"date-parts":[[2025,2,21]]}}}