{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T19:42:10Z","timestamp":1790538130472,"version":"4.1.0"},"reference-count":60,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T00:00:00Z","timestamp":1602201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100013437","name":"Ohio Soybean Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013437","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Monsanto Bayer Insect Management Knowledge Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Host-plant resistance (HPR) is an important tool for pest management, affording both economic and environmental benefits. The mechanisms of aphid resistance in soybean are not well understood, but likely involve the induction of the jasmonic acid (JA) pathway, and possibly other phytohormone signals involved in plant defense responses. Despite the efficacy of aphid resistance in soybean, virulent aphids have overcome this resistance through mostly unknown mechanisms. Here, we have used metabolomic tools to define the role of plant phytohormones, especially the JA pathway, in regulating interactions between aphid-resistant soybean and virulent aphids. We hypothesized that virulent aphids avoid or suppress the JA pathway to overcome aphid resistance. Our results suggested that aphid-resistant soybean increased accumulation of JA-isoleucine (JA-Ile) only when infested with avirulent aphids; virulent aphids did not cause induction of JA-Ile. Further, applying JA-Ile to aphid-resistant soybean reduced subsequent virulent aphid populations. The concentrations of other phytohormones remained unchanged due to aphid feeding, highlighting the importance of JA-Ile in this interaction. These results increase our knowledge of soybean resistance mechanisms against soybean aphids and contribute to our understanding of aphid virulence mechanisms, which will in turn promote the durability of HPR.<\/jats:p>","DOI":"10.1093\/jee\/toaa221","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T03:39:55Z","timestamp":1599709195000},"page":"2972-2978","source":"Crossref","is-referenced-by-count":32,"title":["Jasmonic Acid-Isoleucine (JA-Ile) Is Involved in the Host-Plant Resistance Mechanism Against the Soybean Aphid (Hemiptera: Aphididae)"],"prefix":"10.1093","volume":"113","author":[{"given":"Ashley D","family":"Yates-Stewart","sequence":"first","affiliation":[{"name":"Center for Applied Plant Sciences, The Ohio State University, CFAES Wooster Campus, Wooster, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Pekarcik","sequence":"additional","affiliation":[{"name":"Department of Entomology, The Ohio State University, CFAES Wooster Campus, Wooster, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2953-9187","authenticated-orcid":false,"given":"Andy","family":"Michel","sequence":"additional","affiliation":[{"name":"Center for Applied Plant Sciences, The Ohio State University, CFAES Wooster Campus, Wooster, OH"},{"name":"Department of Entomology, The Ohio State University, CFAES Wooster Campus, Wooster, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua J","family":"Blakeslee","sequence":"additional","affiliation":[{"name":"Center for Applied Plant Sciences, The Ohio State University, CFAES Wooster Campus, Wooster, OH"},{"name":"Laboratory for the Analysis of Metabolites from Plants and Department of Horticulture and Crop Sciences, The Ohio State University, Wooster, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,10,9]]},"reference":[{"key":"2020120907241092100_CIT0001","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.2135\/cropsci2012.11.0672","article-title":"Soybean aphid biotype 4 identified","volume":"53","author":"Alt","year":"2013","journal-title":"Crop Sci"},{"key":"2020120907241092100_CIT0002","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1186\/1471-2164-15-972","article-title":"RNA-Seq reveals a xenobiotic stress response in the soybean aphid, Aphis glycines, when fed aphid-resistant soybean","volume":"15","author":"Bansal","year":"2014","journal-title":"BMC Genomics"},{"key":"2020120907241092100_CIT0003","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/978-1-4939-3356-3_5","article-title":"Microscopic and biochemical visualization of auxins in plant tissues,","volume-title":"Environ. responses plants, methods in molecular biology","author":"Blakeslee","year":"2016"},{"key":"2020120907241092100_CIT0004","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1146\/annurev.phyto.41.052002.095505","article-title":"Signal crosstalk and induced resistance: straddling the line between cost and benefit","volume":"43","author":"Bostock","year":"2005","journal-title":"Annu. 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