{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:24:50Z","timestamp":1787009090453,"version":"build-2736575974"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Faculty of Science, Kasetsart University"},{"name":"ISB funding"},{"DOI":"10.13039\/501100004539","name":"Kasetsart University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004539","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005621","name":"Kasetsart University Research and Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014795","name":"Center of Excellence for Innovation in Chemistry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014795","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Higher Education, Science Research and Innovation"},{"name":"Ministry of Higher Education, Science, Research and Innovation"},{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Kasetsart University Reinventing University Program 2021"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Artocarpus lacucha, a plant in the Moraceae family, has traditionally been used in Southeast Asian medicine to treat various ailments. This study investigated the insecticidal potential against Spodoptera litura of several compounds extracted from A. lacucha using a topical application method. A sequential extraction method was employed with A. lacucha stems to identify the most toxic crude extract by using hexane, dichloromethane, ethyl acetate, and methanol solvents. Subsequently, the most toxic crude extract was analyzed for chemical composition by HPLC, followed by the isolation process. Among these crude extracts, the ethyl acetate crude extract was the most toxic to second-instar S. litura larvae (24-h LD50 value of ~9.07 \u00b5g\/larva). Our results showed that the catechin isolated from the ethyl acetate crude extract exhibited the highest toxicity against this insect (24-h LD50 value of ~8.37 \u00b5g\/larva). Additionally, catechin significantly decreased the activities of acetylcholinesterase, carboxylesterases, and glutathione S-transferase in the larvae. These findings suggest that catechin isolated from A. lacucha could be a potential insecticidal agent against S. litura. However, the toxicity and persistence of catechin under field conditions need to be further investigated to develop this novel insecticide.<\/jats:p>","DOI":"10.1093\/jee\/toad108","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T20:55:51Z","timestamp":1684961751000},"page":"1205-1210","source":"Crossref","is-referenced-by-count":14,"title":["Potential insecticidal extracts from\n                    <i>Artocarpus lacucha<\/i>\n                    against\n                    <i>Spodoptera litura<\/i>\n                    (Lepidoptera: Noctuidae) larvae"],"prefix":"10.1093","volume":"116","author":[{"given":"Torranis","family":"Ruttanaphan","sequence":"first","affiliation":[{"name":"Biology Program, School of Science, Walailak University , Nakhon Si Thammarat , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weerasak","family":"Songoen","sequence":"additional","affiliation":[{"name":"Central Laboratory and Greenhouse Complex, Faculty of Agriculture Kamphaeng Saen, Kasetsart University, Kamphaeng Saen Campus , Nakhon Pathom 73140 , Thailand"},{"name":"Department of Chemistry, Center of Excellence for Innovation in Chemistry and Special Research Unit for Advanced Magnetic Resonance, Faculty of Science, Kasetsart University , Bangkok 10900 , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9332-9830","authenticated-orcid":false,"given":"Wanchai","family":"Pluempanupat","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Center of Excellence for Innovation in Chemistry and Special Research Unit for Advanced Magnetic Resonance, Faculty of Science, Kasetsart University , Bangkok 10900 , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9192-6375","authenticated-orcid":false,"given":"Vasakorn","family":"Bullangpoti","sequence":"additional","affiliation":[{"name":"Animal Toxicology and Physiology Specialty Research Unit, Department of Zoology, Faculty of Science, Kasetsart University , Bangkok , Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"key":"2023081014085205800_CIT0002","first-page":"23","article-title":"Host plants of leaf worm, Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in Pakistan","volume":"1","author":"Ahmad","year":"2013","journal-title":"Asian J Agric Biol"},{"key":"2023081014085205800_CIT0004","doi-asserted-by":"crossref","first-page":"103646","DOI":"10.1016\/j.ibmb.2021.103646","article-title":"Comparative analysis of the detoxification gene inventory of four major Spodoptera pest species in response to xenobiotics","volume":"138","author":"Amezian","year":"2021","journal-title":"Insect Biochem Mol Biol."},{"issue":"3","key":"2023081014085205800_CIT0005","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3390\/plants9030391","article-title":"Taxonomic notes on the \u2018Mahat\u2019 (Artocarpus lacucha and A. thailandicus, Moraceae) species complex in Thailand","volume":"9","author":"Aneklaphakij","year":"2020","journal-title":"Plants"},{"issue":"8","key":"2023081014085205800_CIT0006","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1002\/cbdv.201300407","article-title":"Insecticidal metabolites from the rhizomes of Veratrum album against adults of colorado potato beetle, Leptinotarsa decemlineata","volume":"11","author":"Aydin","year":"2014","journal-title":"Chem Biodivers."},{"issue":"12","key":"2023081014085205800_CIT0007","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1002\/ps.3742","article-title":"Bioefficacy of the triterpenoid friedelin against Helicoverpa armigera (Hub.) and Spodoptera litura (Fab.) 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