{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T02:58:29Z","timestamp":1787885909621,"version":"build-2784847793"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Dicaffeoyltartaric acid (diCT) and 3,5-dicaffeoylquinic acid (3,5-diCQ) are described for their aphicidal properties on several aphid species. Intending to valorize diCT and 3,5-diCQ as biocontrol products and because of the high adaptive capacities of aphids to xenobiotics, we sought to determine the existence of adaptation first in Myzus persicae (Sulzer) (Hemiptera: Aphididae) and then other aphids. Resistance of aphids to these biopesticides could be promoted by (i) the existence of resistance to synthetic insecticides that may confer cross-resistance and (ii) the presence of these compounds in wild plants likely which may have led to pre-existing adaptation in aphids. We assessed the resistance levels to diCT and 3,5-diCQ in 7 lab strains (including some resistant to synthetic aphicides) and 7 wild populations of M. persicae using biotests. The activities of detoxification enzymes contributing to insecticide resistance were also measured. Additionally, we followed the same method to characterize susceptibility to these caffeic derivatives in wild populations of Nasonovia ribisnigri (Mosley) (Hemiptera: Aphididae), Brevicoryne brassicae(Linnaeus) (Hemiptera: Aphididae) and, Aphis craccivora(Koch) (Hemiptera: Aphididae). Our results show variability in susceptibility to diCT between populations of M. persicae, but resistance ratios (RR) were low (RR\u2005=\u20053.59). We found no cross-resistance between synthetic insecticides and diCT. Carboxylesterase and glutathione-S-transferase did not seem to be involved in its detoxification. A clone of A. craccivora collected from peanut, a species rich in diCT, was not susceptible to either diCT or 3,5-diCQ, suggesting a common molecular target for these 2 molecules and the existence of a high-effect resistance mechanism. These active botanical substances remain good candidates for M. persicae biocontrol in agriculture.<\/jats:p>","DOI":"10.1093\/jee\/toae069","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T11:45:54Z","timestamp":1719575154000},"page":"1347-1355","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of 2 botanical aphicides, chicoric and 3,5-dicaffeoylquinic acids, on aphids susceptible and resistant to synthetic insecticides"],"prefix":"10.1093","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4717-5273","authenticated-orcid":false,"given":"Myriam","family":"Siegwart","sequence":"first","affiliation":[{"name":"INRAE, unit\u00e9 PSH, Plantes et Syst\u00e8mes de culture Horticoles , 84914 Avignon , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Gauffre","sequence":"additional","affiliation":[{"name":"INRAE, unit\u00e9 PSH, Plantes et Syst\u00e8mes de culture Horticoles , 84914 Avignon , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Lecerf","sequence":"additional","affiliation":[{"name":"INRAE, unit\u00e9 PSH, Plantes et Syst\u00e8mes de culture Horticoles , 84914 Avignon , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Po\u00ebssel","sequence":"additional","affiliation":[{"name":"INRAE, unit\u00e9 GAFL, G\u00e9n\u00e9tique et Am\u00e9lioration des Fruits et L\u00e9gumes , 84143 Montfavet , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"2024081216415495000_CIT0001","first-page":"241","article-title":"Differential accumulation of energy by the colour morphs of the pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) mirrors their ecological adaptations","volume-title":"Eur J Entomol","author":"Ahsaei","year":"2013"},{"key":"2024081216415495000_CIT0002","first-page":"1299","article-title":"Caffeoylquinic acids: chemistry, biosynthesis, occurrence, analytical challenges, and bioactivity","volume-title":"Plant J","author":"Alc\u00e1zar Maga\u00f1a","year":"2021"},{"key":"2024081216415495000_CIT0003","first-page":"33","article-title":"Adaptation to toxic hosts as a factor in the evolution of insecticide resistance","volume-title":"Curr Opin Insect Sci","author":"Alyokhin","year":"2017"},{"key":"2024081216415495000_CIT0004","first-page":"41","article-title":"The evolution of insecticide resistance in the peach potato aphid, Myzus persicae","volume-title":"Insect Biochem Mol Biol","author":"Bass","year":"2014"},{"key":"2024081216415495000_CIT0005","volume-title":"lme4: linear mixed-effects models using Eigen and S4. 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