{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:02:37Z","timestamp":1787580157987,"version":"build-2736575974"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Biosafety SA-Technology Innovation Agency-Department of Science"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The strategic use of refuge areas is a well-known method for delaying the development of pest resistance to Bacillus thuringiensis (Bt) crop. A lesser-known method to control against resistance development is sterile insect releases. In this article, an agent-based simulation model is used to test the effectiveness of combining the use of Bt sugarcane, refuge areas, and sterile insect releases as an integrated strategy against Eldana saccharina Walker (Lepidoptera: Pyralidae) infestation and resistance development. Individual insects are modeled with their own genetic traits on a simulated sugarcane field that represents either Bt or refuge area. The model is applied to 2 hypothetical case studies. In the first experiment, resistance development and infestation dynamics in Bt sugarcane without refuge areas are considered using various sterile:wild sterile release ratios, and different release distributions. In the second experiment, the inclusion of a refuge area in Bt sugarcane is considered, using various sterile:wild releases ratios and different release distributions. A trade-off between sterile insect releases and the use of the refuge area was observed, and could, in some cases, work against each other.<\/jats:p>","DOI":"10.1093\/jee\/toae248","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T22:26:02Z","timestamp":1730931962000},"page":"339-350","source":"Crossref","is-referenced-by-count":1,"title":["Combining sterile insect releases with refuge areas to delay the evolution of resistance to Bt sugarcane: an agent-based modeling approach"],"prefix":"10.1093","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6837-6037","authenticated-orcid":false,"given":"Linke","family":"Potgieter","sequence":"first","affiliation":[{"name":"Department of Logistics, Faculty of Economics and Business Management, Stellenbosch University , Stellenbosch ,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2208-5071","authenticated-orcid":false,"given":"Dirk J","family":"Human","sequence":"additional","affiliation":[{"name":"Department of Logistics, Faculty of Economics and Business Management, Stellenbosch University , Stellenbosch ,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Downing","sequence":"additional","affiliation":[{"name":"Department of Logistics, Faculty of Economics and Business Management, Stellenbosch University , Stellenbosch ,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"2025021218472559200_CIT0001","author":"Aroian","year":"2018"},{"issue":"1","key":"2025021218472559200_CIT0051","first-page":"1","article-title":"The sterile insect technique in agricultural crops in South Africa: a metamorphosis.... but will it fly? 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