{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T22:09:44Z","timestamp":1779228584538,"version":"3.51.4"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,4,21]],"date-time":"2021-04-21T00:00:00Z","timestamp":1618963200000},"content-version":"vor","delay-in-days":141,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81904226"],"award-info":[{"award-number":["81904226"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81873327"],"award-info":[{"award-number":["81873327"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The pathological progression and prognosis of traumatic femur head necrosis (TFHN) after femoral neck fracture (FNF) in children and adolescent is relatively unknown and has never been specifically characterized. As we speculated, the prognosis in such population would be poor and characterized as the high risk of femoral head collapse, hip deformity and degeneration in a short term. This retrospective case series enrolled 64 children and adolescent with TFHN who treated with observational treatment from 2000.1 to 2018.1. The primary outcomes, the progression of femoral head collapse, hip deformity (Stulberg classification) and hip degeneration (T\u00f6nnis grade), and their prognostic factors were analysed. Sixty-four patients with a mean age of 13\u2009years (6\u201316\u2009years) were included. A total of 28 hips (44%) showed unsatisfactory outcome and 25 (39%) hips collapsed progressively during a mean follow-up of 48\u2009months (24\u2013203\u2009months). Finally, 38 hips (59%) experienced hip deformity, 20 of them were Class IV\/V. Thirty-four hips (53%) generally progressed to osteoarthritis, 14 of them were classified as Grades II\/III. The location of the lesion and the presence of subluxation were found to be related to progression of collapse; however, the presence of subluxation was the only independent risk factor of severe hip deformity and degeneration. TFHN in children and adolescent is a rapidly progressing disease with a poor prognosis characterized by a high risk of femoral head collapse progression. If the subluxation emerged, collapsed cases showed increasingly tendency towards hip deformity and degeneration.<\/jats:p>","DOI":"10.1093\/jhps\/hnab025","type":"journal-article","created":{"date-parts":[[2021,4,21]],"date-time":"2021-04-21T09:32:22Z","timestamp":1618997542000},"page":"696-704","source":"Crossref","is-referenced-by-count":6,"title":["Pathological progress of traumatic femur head necrosis after femoral neck fracture in children and adolescents: a case series study"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3160-8652","authenticated-orcid":false,"given":"Fan","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhikun","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"},{"name":"Department of Joint Diseases, Quanzhou Orthopedic-traumatological Hospital of Fujian Traditional Chinese Medicine University, No.61, Citong western road, Quanzhou city, Fujian province, 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonggang","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"},{"name":"Department of Orthopaedics, Dongguan Eastern Central Hospital, No. 88, Changdong Road, Changping Town, Dongguan city, Guangdong province, 510000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhinan","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"},{"name":"Department of Joint Diseases, Traumatology & Orthopedics Institute of Guangzhou University of Chinese Medicine, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou city, Guangdong province, 510000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengxiang","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"He","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"},{"name":"Department of Joint Diseases, Traumatology & Orthopedics Institute of Guangzhou University of Chinese Medicine, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou city, Guangdong province, 510000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiushi","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"},{"name":"Department of Joint Diseases, Traumatology & Orthopedics Institute of Guangzhou University of Chinese Medicine, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou city, Guangdong province, 510000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziqi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics & Traumatology, Lingnan Medical Research Center, Guangzhou University of Chinese Medicine,\u00a0No.12, airport road, Baiyun distinct, Guangzhou city, Guangdong province, 510000, China"},{"name":"Department of Joint Diseases, Traumatology & Orthopedics Institute of Guangzhou University of Chinese Medicine, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou city, Guangdong province, 510000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,4,20]]},"reference":[{"key":"2021080819301614700_hnab025-B1","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1302\/0301-620X.44B3.528","article-title":"Fractures of the neck of the femur in children","volume":"44-B","author":"Ratliff","year":"1962","journal-title":"J Bone Joint Surg Br"},{"key":"2021080819301614700_hnab025-B2","first-page":"504","article-title":"Avascular necrosis of the head of the femur, after fractures of the femoral neck in children, and Perthes' disease","volume":"55","author":"Ratliff","year":"1962","journal-title":"Proc R Soc Med"},{"key":"2021080819301614700_hnab025-B3","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1302\/0301-620X.95B1.30161","article-title":"Factors affecting the outcome of fractures of the femoral neck in children and adolescents: a systematic 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