{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:36:26Z","timestamp":1790696186836,"version":"4.1.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T00:00:00Z","timestamp":1635465600000},"content-version":"vor","delay-in-days":58,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31860513"],"award-info":[{"award-number":["31860513"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31760526"],"award-info":[{"award-number":["31760526"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004761","name":"Natural Science Foundation of Hainan Province","doi-asserted-by":"publisher","award":["2019RC121"],"award-info":[{"award-number":["2019RC121"]}],"id":[{"id":"10.13039\/501100004761","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Radiation is considered as a promising insect pest control strategy for minimizing postharvest yield losses. Among various techniques, irradiation is a method of choice as it induces lethal biochemical or molecular changes that cause a downstream cascade of abrupt physiological abnormalities at the cellular level. In this study, we evaluated the effect of 60Co-\u03b3 radiation on various developmental stages of Zeugodacus cucurbitae Coquillett and subsequent carry-over effects on the progeny. For this purpose, we treated eggs with 30- and 50-Gy radiation doses of 60Co-\u03b3. We found that radiation significantly affected cellular antioxidants, insect morphology, and gene expression profiles. Our results indicate that in response to various doses of irradiation reactive oxygen species, catalase, peroxidase, and superoxide dismutase activities were increased along with a significant increase in the malondialdehyde (MDA) content. We observed higher mortality rates during the pupal stage of the insects that hatched from irradiated eggs (50 Gy). Furthermore, the life span of the adults was reduced in response to 50 Gy radiation. The negative effects carried over to the next generation were marked by significantly lower fecundity in the F1 generation of the irradiation groups as compared to control. The radiation induced morphological abnormalities at the pupal, as well as the adult, stages. Furthermore, variations in the gene expression following irradiation are discussed. Taken together, our results signify the utility of 60Co-\u03b3 radiation for fruit fly postharvest management.<\/jats:p>","DOI":"10.1093\/jisesa\/ieab080","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T11:20:39Z","timestamp":1633087239000},"source":"Crossref","is-referenced-by-count":10,"title":["60Co-\u03b3 Radiation Alters Developmental Stages of <i>Zeugodacus cucurbitae<\/i> (Diptera: Tephritidae) Through Apoptosis Pathways Gene Expression"],"prefix":"10.1093","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2383-0798","authenticated-orcid":false,"given":"Shakil","family":"Ahmad","sequence":"first","affiliation":[{"name":"School of Plant Protection, Hainan University, Haikou, Hainan Province, 570228, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7803-429X","authenticated-orcid":false,"given":"Adil","family":"Hussain","sequence":"additional","affiliation":[{"name":"Department of Entomology, Abdul Wali Khan University Mardan, 23200, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6174-1425","authenticated-orcid":false,"given":"Farman","family":"Ullah","sequence":"additional","affiliation":[{"name":"Department of Plant Biosecurity, College of Plant Protection, China Agricultural University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3639-5705","authenticated-orcid":false,"given":"Momana","family":"Jamil","sequence":"additional","affiliation":[{"name":"School of Plant Protection, Hainan University, Haikou, Hainan Province, 570228, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8194-5094","authenticated-orcid":false,"given":"Asad","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Entomology, Abdul Wali Khan University Mardan, 23200, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saqib","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Agriculture, University of Swabi, Ambar, Khyber Pakhtunkhwa 94640, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1948-715X","authenticated-orcid":false,"given":"Yanping","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Plant Protection, Hainan University, Haikou, Hainan Province, 570228, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,10,29]]},"reference":[{"key":"2021103117582324700_CIT0001","first-page":"691382","article-title":"RNAi-Mediated Knockdown of Imaginal Disc Growth Factors (IDGFs) genes causes developmental malformation and mortality in melon fly, Zeugodacus cucurbitae","volume-title":"Front. Genet.","author":"Ahmad","year":"2021"},{"key":"2021103117582324700_CIT0002","first-page":"248","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume-title":"Anal. Biochem.","author":"Bradford","year":"1976"},{"key":"2021103117582324700_CIT0003","first-page":"a012559","article-title":"DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation","volume-title":"Cold Spring Harb. Perspect. 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