{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T10:20:07Z","timestamp":1772533207209,"version":"3.50.1"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T00:00:00Z","timestamp":1583107200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100009647","name":"Ministry of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009647","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17H01585"],"award-info":[{"award-number":["17H01585"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Cancer Center Research and Development","award":["29-A-3"],"award-info":[{"award-number":["29-A-3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The purpose of this systematic review is to assess and compare the efficacy of surgical treatment for patients with asymptomatic extra-peritoneal desmoid-type fibromatosis to the wait-and-see policy by evaluating (1) the exacerbation rate (exacerbation; recurrence after surgery or progressive disease following non-surgical treatment) and (2) treatment-associated complications in extra-peritoneal desmoid-type fibromatosis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We evaluated documents published between 1 January 1990 and 31 August 2017. The risk of bias in the selected literature was analyzed using the Cochrane Collaboration Risk of Bias Tool. Quality of evidence was evaluated using Grading of Recommendation, Assessment, Development and Evaluation approach.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>One prospective cohort study, four case\u2013control studies and five case series studies were identified. Meta-analysis was performed to evaluate the exacerbation rate after treatment on one prospective cohort study and four case\u2013control studies. In comparing surgical and non-surgical treatments, the exacerbation rate was significantly higher in the surgical treatment group (odds ratio: 1.32, 95% confidence interval 1.01\u20131.73, P\u00a0=\u00a00.05). However, in the case series study, the recurrence rate was 23.4% for the surgical treatment group, while the progressive disease rate was 28.1% for the non-surgical treatment group. The postoperative complication rates associated with surgical treatment in the two studies were 20.8 and 17.2%, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>When considering the exacerbation rate, non-surgical treatment might be appropriate for asymptomatic patients with extra-peritoneal desmoid-type fibromatosis. However, if patients with tumor-related symptoms opt for surgery, including those who face difficulties due to the presence of tumors, it is important to fully explain to them the possibility that the recurrence rate and treatment-associated functional failures may increase depending on the site of occurrence.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jjco\/hyaa009","type":"journal-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T12:11:51Z","timestamp":1579003911000},"page":"574-580","source":"Crossref","is-referenced-by-count":6,"title":["Usefulness of surgical treatment for asymptomatic patients with extra-peritoneal desmoid-type fibromatosis: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"50","author":[{"given":"Munehisa","family":"Kito","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Ogose","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Yoshida","sequence":"first","affiliation":[{"name":"Department of Hemodialysis and Surgery, Ichikawa Hospital, International University of Health and Welfare, Chiba, Japan"},{"name":"Department of EBM and Guidelines, Japan Council for Quality Health Care, Tokyo, Japan, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Nishida","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,3,2]]},"reference":[{"key":"2020050701580977100_ref1","volume-title":"WHO Classification of Tumours of Soft Tissue and Bone","author":"Fletcher","year":"2013","edition":"4th"},{"key":"2020050701580977100_ref2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ejca.2014.11.019","article-title":"Sporadic extra abdominal wall desmoid-type fibromatosis: surgical resection can be safely limited to a minority of patients","volume":"51","author":"Colombo","year":"2015","journal-title":"Eur J Cancer"},{"key":"2020050701580977100_ref3","doi-asserted-by":"crossref","first-page":"4096","DOI":"10.1245\/s10434-013-3197-x","article-title":"Spontaneous regression of primary abdominal wall desmoid tumors: more common than previously thought","volume":"20","author":"Bonvalot","year":"2013","journal-title":"Ann Surg 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Rating the quality of evidence","volume":"64","author":"Balshem","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"2020050701580977100_ref14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ejca.2017.06.017","article-title":"Surgical versus non-surgical approach in primary desmoid-type fibromatosis patients: a nationwide prospective cohort from the French sarcoma group","volume":"83","author":"Penel","year":"2017","journal-title":"Eur J Cancer"},{"key":"2020050701580977100_ref15","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jss.2016.06.028","article-title":"Conservative management of desmoid tumors is safe and effective","volume":"205","author":"Park","year":"2016","journal-title":"J Surg Res"},{"key":"2020050701580977100_ref16","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.amjsurg.2013.08.007","article-title":"Prognostic factors influencing event-free survival and treatments in desmoid-type fibromatosis: analysis from a large institution","volume":"207","author":"Huang","year":"2014","journal-title":"Am J Surg"},{"key":"2020050701580977100_ref17","doi-asserted-by":"crossref","first-page":"3553","DOI":"10.1200\/JCO.2010.33.5489","article-title":"Prognostic factors influencing progression-free survival determined from a series of sporadic desmoid tumors: a wait-and-see policy according to tumor presentation","volume":"29","author":"Salas","year":"2011","journal-title":"J Clin Oncol"},{"key":"2020050701580977100_ref18","doi-asserted-by":"crossref","first-page":"7513","DOI":"10.1007\/s13277-014-2002-1","article-title":"Prognostic factors for desmoid tumor: a surgical series of 233 patients at a single institution","volume":"35","author":"Zeng","year":"2014","journal-title":"Tumour Biol"},{"key":"2020050701580977100_ref19","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/SLA.0b013e31828c8a30","article-title":"A prognostic nomogram for prediction of recurrence in desmoid fibromatosis","volume":"258","author":"Crago","year":"2013","journal-title":"Ann Surg"},{"key":"2020050701580977100_ref20","doi-asserted-by":"crossref","first-page":"4036","DOI":"10.1245\/s10434-012-2634-6","article-title":"Management and recurrence patterns of desmoids tumors: a multi-institutional analysis of 211 patients","volume":"19","author":"Peng","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"2020050701580977100_ref21","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surg"},{"key":"2020050701580977100_ref22","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ejca.2014.11.005","article-title":"Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients\u2019 and professionals\u2019 expertise - a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer\/soft tissue and bone sarcoma group initiative","volume":"51","author":"Kasper","year":"2015","journal-title":"Eur J Cancer"},{"key":"2020050701580977100_ref23","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.ejso.2016.02.012","article-title":"Extra-abdominal desmoid fibromatosis: a review of management, current guidance and unanswered questions","volume":"42","author":"Eastley","year":"2016","journal-title":"Eur J Surg Oncol"},{"key":"2020050701580977100_ref24","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1245\/s10434-018-6408-7","article-title":"Systematic review of clinical outcomes following various treatment options for patients with extraabdominal desmoid tumors","volume":"25","author":"Smith","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"2020050701580977100_ref25","author":"Network"},{"key":"2020050701580977100_ref26","doi-asserted-by":"crossref","first-page":"iv51","DOI":"10.1093\/annonc\/mdy096","article-title":"Soft tissue and visceral sarcomas: ESMO-EURACAN clinical practice guidelines for diagnosis, treatment and follow-up","volume":"29","author":"Casali","year":"2018","journal-title":"Ann Oncol"},{"key":"2020050701580977100_ref27","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/jso.21433","article-title":"Extra-abdominal desmoid tumors: a report of 234 cases","volume":"102","author":"Mankin","year":"2010","journal-title":"J Surg Oncol"},{"key":"2020050701580977100_ref28","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.amsu.2017.03.023","article-title":"Outcome of surgery for primary and recurrent desmoid-type fibromatosis. 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