{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T19:06:36Z","timestamp":1780772796675,"version":"3.54.1"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100010101","name":"Taichung Veterans General Hospital","doi-asserted-by":"publisher","award":["TCVGH-1077003C"],"award-info":[{"award-number":["TCVGH-1077003C"]}],"id":[{"id":"10.13039\/501100010101","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>For recurrent laryngeal cancers, trans-oral robotic surgery has been used to perform total laryngectomy, but limited cases had been reported without long-term outcome follow-up. This study aims at presenting the largest longitudinal retrospective cohort in a single tertiary referral medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From November 2013 to August 2017, seven patients with recurrent laryngeal cancers without evidence of neck metastasis were selected to receive trans-oral robotic surgery-assisted TL without neck dissection. The para-operative details including the surgical success rates, surgical methods, resection extent, drainage tube placement, pharyngeal wound closure, console surgical time, pathologic findings and long-term complications were reviewed and described. The study end points include survival rates and preservation of swallowing function without tube feeding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Trans-oral robotic surgery-assisted total laryngectomy was successfully performed on all seven patients with mean surgical console time of 111\u00a0\u00b1\u00a066 min. Strap muscles and hyoid bone were resected like open surgery in six and five patients, respectively. For all the seven patients, there was no severe pharyngo-cutaneous fistula formation requiring repair in a second surgery, but tracheostoma stenosis was not uncommon (57%). Three patients received adjuvant chemotherapy\/radiotherapy. After follow-up of 36.1\u00a0\u00b1\u00a015.8\u00a0months, two patients had neck recurrence, and one patient died 19\u00a0months after surgery, but the other five patients were alive without disease recurrence. The overall survival rate was 85.7% (6\/7), and all patients had good swallowing function without tube feeding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Trans-oral robotic surgery-assisted total laryngectomy is a feasible approach for selected patients with recurrent laryngeal cancers. The oncologic and functional outcomes were satisfactory. Further larger cohort study is worthwhile to further elucidate the value of trans-oral robotic surgery-assisted total laryngectomy.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jjco\/hyaa034","type":"journal-article","created":{"date-parts":[[2020,2,29]],"date-time":"2020-02-29T12:23:36Z","timestamp":1582979016000},"page":"653-660","source":"Crossref","is-referenced-by-count":9,"title":["Long-term outcomes of trans-oral robotic surgery-assisted total laryngectomy for recurrent laryngeal cancers"],"prefix":"10.1093","volume":"50","author":[{"given":"Chen-Chi","family":"Wang","sequence":"first","affiliation":[{"name":"School of Medicine, National Yang-Ming University, Taipei"},{"name":"School of Speech Language Pathology and Audiology, Chung Shan Medical University, Taichung"},{"name":"Department of Audiology and Speech-Language Pathology, Asia University, Taichung"},{"name":"Department of Otolaryngology-Head and Neck Surgery, Taichung Veterans General Hospital, Taichung"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Jiun","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Taichung Veterans General Hospital, Taichung"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"De Virgilio","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Unit, Humanitas University, Humanitas Clinical and Research Center-IRCCS, Rozzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-An","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang-Ming University, Taipei"},{"name":"Department of Otolaryngology-Head and Neck Surgery, Taichung Veterans General Hospital, Taichung"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Hwa","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Audiology and Speech-Language Pathology, Asia 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