{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T09:33:30Z","timestamp":1740130410221,"version":"3.37.3"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T00:00:00Z","timestamp":1637020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology of Japan","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Adolescents and young adults with cancer encounter age-related challenges. Cancer treatment and support are not always tailored to the needs of each patient due to difficulty in the collection of accurate data. The present study aimed to investigate cancer among children and adolescents and young adults in the four adjacent prefectures of Japan (Toyama, Ishikawa, Fukui and Nagano) by analyzing data from a unique regional cancer database. We retrieved and analyzed the data of pediatric and adolescent and young adult patients aged between 0 and 39\u00a0years at cancer diagnosis (including carcinoma in situ), which was registered in the Hokushin Ganpro database between 2010 and 2015. A total of 5718 cases (1571 males and 4147 females) were identified during this period. The overall male-to-female ratio was 1:2.6. There was no distinct difference in the number of cancer cases per 100\u00a0000 population between males and females until 19\u00a0years of age. The difference became more pronounced after 20\u00a0years of age. The number of cancer cases (per 100\u00a0000 population) in the 0\u201314-, 15\u201319-, 20\u201329- and 30\u201339-year age groups was estimated to be 13.4, 14.5, 44.0 and 101.5, respectively. Carcinomas were the most common type of cancer in the adolescents and young adults (15\u201339\u00a0years) population (74%), whereas they were not the predominant cancer type in the pediatric (0\u201314\u00a0years) population. Although further research is needed to understand the needs of adolescents and young adults with cancer, we believe that our findings will help guide efforts to improve the management strategy for adolescents and young adults with cancer.<\/jats:p>","DOI":"10.1093\/jjco\/hyab174","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T11:10:55Z","timestamp":1634814655000},"page":"86-95","source":"Crossref","is-referenced-by-count":3,"title":["Cancer among children, adolescents and young adults in the Hokushin region, Japan, between 2010 and 2015"],"prefix":"10.1093","volume":"52","author":[{"given":"Eri","family":"Okura","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikazu","family":"Nishino","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, Kanazawa Medical University, Uchinada, Ishikawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Sakashita","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology and Oncology, Nagano Children\u2019s Hospital, Azumino, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azusa","family":"Tanimoto","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuji","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology, Toyama University Hospital, Toyama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsutoshi","family":"Nakada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonobu","family":"Koizumi","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Cancer Therapy, Shinshu University School of Medicine, Matsumoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Yano","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0793-815X","authenticated-orcid":false,"given":"Yozo","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"key":"2022010310245852100_ref1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s12185-013-1364-2","article-title":"Incidence and survival rates of hematological malignancies in Japanese children and adolescents (2006-2010): based on registry data from the Japanese Society of Pediatric Hematology","volume":"98","author":"Horibe","year":"2013","journal-title":"Int J Hematol"},{"key":"2022010310245852100_ref2","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1200\/JCO.2017.77.0180","article-title":"Surveillance for late effects in childhood cancer survivors","volume":"36","author":"Landier","year":"2018","journal-title":"J Clin Oncol"},{"key":"2022010310245852100_ref3","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1159\/000484936","article-title":"Late effects and long-term follow-up after 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