{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T09:40:23Z","timestamp":1778924423730,"version":"3.51.4"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Shanghai Municipal Commission of Health and Family Planning","award":["21DZ2208300"],"award-info":[{"award-number":["21DZ2208300"]}]},{"DOI":"10.13039\/501100003399","name":"Shanghai Science and Technology Committee","doi-asserted-by":"publisher","award":["16411954200"],"award-info":[{"award-number":["16411954200"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Sarcopenia, overweight and obesity are all dynamic changes in body composition, which may have a negative effect on the prognosis for patients with colorectal cancer. The aim of this study was to investigate the predictive role of sarcopenia on overweight or obese patients with colorectal cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted an observative study on the population of overweight or obese patients with colorectal cancer who underwent curative surgeries in two centers between 2015 and 2021. They were grouped by the presence of sarcopenia. Propensity score match analysis was used to balance the baseline of clinicopathologic characteristics of the two groups. Then, the postoperative outcomes between the two groups were compared. Independent risk factors were evaluated for complications using univariate and multivariate analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 827 patients enrolled, 126 patients were matched for analysis. Patients with sarcopenia had a higher incidence of total complication and medical complications, a higher rate of laparoscopic surgery performed and higher hospitalization costs. Old age (\u226565\u00a0years, P\u00a0=\u00a00.012), ASA grade (III, P\u00a0=\u00a00.008) and sarcopenia (P\u00a0=\u00a00.036) were independent risk factors for total complications. ASA grade (III, P\u00a0=\u00a00.002) and sarcopenia (P\u00a0=\u00a00.017) were independent risk factors for medical complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Sarcopenia was prevalent among overweight or obese patients with colorectal cancer and was associated with negative postoperative outcomes. Early recognition of changes in body composition could help surgeons be well prepared for surgical treatment for overweight or obese patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jjco\/hyad139","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T07:56:02Z","timestamp":1697615762000},"page":"23-30","source":"Crossref","is-referenced-by-count":3,"title":["Clinical impact of sarcopenia for overweight or obese patients with colorectal cancer"],"prefix":"10.1093","volume":"54","author":[{"given":"Wei-Zhe","family":"Chen","sequence":"first","affiliation":[{"name":"Tongji University School of Medicine Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, , Shanghai"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Lin","sequence":"additional","affiliation":[{"name":"Tongji University School of Medicine Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, , Shanghai"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ding-Ye","family":"Yu","sequence":"additional","affiliation":[{"name":"Shanghai Huadong Hospital Affiliated to Fudan University Department of General Surgery, , Shanghai"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Ren","sequence":"additional","affiliation":[{"name":"Tongji University School of Medicine Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, , Shanghai"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng-Min","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tongji University School of Medicine Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, , Shanghai"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi-Le","family":"Shen","sequence":"additional","affiliation":[{"name":"Tongji University School of Medicine Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, , Shanghai"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai Huadong Hospital Affiliated to Fudan University Department of General Surgery, , Shanghai"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian-Tong","family":"Dong","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Wenzhou Medical University Department of Gastrointestinal Surgery, , Wenzhou , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Yu","sequence":"additional","affiliation":[{"name":"Tongji University School of Medicine Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, , 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