{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T20:21:22Z","timestamp":1787689282356,"version":"build-2784847793"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Japanese Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["Cancer Control-General-23EA1033"],"award-info":[{"award-number":["Cancer Control-General-23EA1033"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We aimed at assessing 15-year trends in 5-year net survival for men diagnosed with prostate cancer during 2000\u20132014 and registered by 16 Japanese regional population-based cancer registries included in the CONCORD-3 study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included data on adult men (15\u201399\u00a0years) diagnosed with prostate cancer during 2000\u20132014 and followed-up to 31 December 2014. We grouped patients into five age groups (15\u201354, 55\u201364, 65\u201374, 75\u201384, and 85\u201399\u00a0years) and four morphology groups according to the ICD-O-3 classification (epithelial, neuroendocrine, other specified morphologies, and malignant neoplasm, not otherwise specified). We grouped patients by stage at diagnosis into localized, regional, and advanced disease. We estimated 5-year net survival by age group, morphological subtype and stage using the Pohar Perme estimator, correcting for background mortality. All-ages estimates were standardized with the International Cancer Survival Standard weights.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Age-standardized 5-year net survival increased over time, from 85.9% in 2000\u20132004 to 93.0% in 2010\u20132014. Survival was higher than 90% for epithelial tumors, and for localized and regional disease. Five-year net survival for patients with distant metastasis was poor at 47.3% (95% CI. 39.4\u201355.1%) during 2010\u20132014.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The improvement in survival for prostate cancer may be due to the high and increasing proportion of patients with localized disease and with epithelial tumors, for which 5-year survival approaches 100%. A comprehensive analysis of long-term survival over a longer period of time would be essential to investigate further the factors contributing to the increasing trend in survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jjco\/hyaf021","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T07:13:36Z","timestamp":1737357216000},"page":"i87-i93","source":"Crossref","is-referenced-by-count":3,"title":["Trends in net survival for prostate cancer in Japan, 2000\u201314 (CONCORD-3)"],"prefix":"10.1093","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4626-0644","authenticated-orcid":false,"given":"Rina","family":"Tanaka","sequence":"first","affiliation":[{"name":"Department of Medical Informatics, Hirosaki University Graduate School of Medicine , 5 Zaifu-Cho Hirosaki City, Aomori , 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Sannomiya, Koshigaya, Saitama , 343-8540,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Shibata","sequence":"additional","affiliation":[{"name":"Yamagata Prefectural Central Hospital, 1800 Oaza-Aoyanagi, Yamagata , Yamagata , 990-2214,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9782-8637","authenticated-orcid":false,"given":"Kayo","family":"Nakata","sequence":"additional","affiliation":[{"name":"Cancer Control Center, Osaka International Cancer Institute , 3-1-69 Otemae, Chuo-ku, Osaka , Osaka, 541-8567,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari","family":"Kajiwara Saito","sequence":"additional","affiliation":[{"name":"Cancer Control Center, Osaka International Cancer Institute , 3-1-69 Otemae, Chuo-ku, Osaka , Osaka, 541-8567,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8199-3037","authenticated-orcid":false,"given":"Masashi","family":"Matsuzaka","sequence":"additional","affiliation":[{"name":"Hirosaki University Hospital , 53 Hon-Cho, Hirosaki, Aomori , 036-8563,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0712-2505","authenticated-orcid":false,"given":"Marisa","family":"Nishio","sequence":"additional","affiliation":[{"name":"Division of Prevention, National Cancer Center , 5-1-1 Tsukiji, Chuo-ku, Tokyo , 104-0045,","place":["Japan"]},{"name":"Department of Medical Statistics , Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki, Osaka 569-8686,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0762-1147","authenticated-orcid":false,"given":"Isao","family":"Oze","sequence":"additional","affiliation":[{"name":"Aichi Cancer Center Research Institute , 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi , 464-8681,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6155-5283","authenticated-orcid":false,"given":"Kaname","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Cancer Prevention and Control Division, Kanagawa Cancer Center Research Institute , 2-3-2 Nakao, Asahi-ku, Yokohama, Kanagawa , 241-8515,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0331-3235","authenticated-orcid":false,"given":"Laureline","family":"Gatellier","sequence":"additional","affiliation":[{"name":"Division of International Health Policy 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371-0005,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuki","family":"Kurosawa","sequence":"additional","affiliation":[{"name":"Ibaraki Prefectural Office, 978-6 Kasahara-Cho, Mito , Ibaraki , 310-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Nemoto","sequence":"additional","affiliation":[{"name":"Ibaraki Pharmaceutical Association Inspection Center, 978-47 Kasahara-Cho, Mito , Ibaraki , 310-0852,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0383-4911","authenticated-orcid":false,"given":"Hiroto","family":"Narimatsu","sequence":"additional","affiliation":[{"name":"Cancer Prevention and Control Division, Kanagawa Cancer Center Research Institute , 2-3-2 Nakao, Asahi-ku, Yokohama, Kanagawa , 241-8515,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiki","family":"Kanemura","sequence":"additional","affiliation":[{"name":"Miyagi Cancer Center Research Institute, 47-1 Nodayama, Medeshima-Shiode, Natori , Miyagi , 981-1293,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isao","family":"Miyashiro","sequence":"additional","affiliation":[{"name":"Cancer Control Center, Osaka International Cancer Institute , 3-1-69 Otemae, Chuo-ku, Osaka , Osaka, 541-8567,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Mori","sequence":"additional","affiliation":[{"name":"Saga-Ken Medical Centre Koseikan, 400 Nakabaru, Kasemachi, Saga , Saga , 840-8571,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Fujita","sequence":"additional","affiliation":[{"name":"Tochigi Cancer Center, 4-9-13 Yohnan, Utsunomiya , Tochigi , 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