{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T09:07:10Z","timestamp":1773392830157,"version":"3.50.1"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T00:00:00Z","timestamp":1746316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Low preoperative skeletal muscle mass is a negative prognostic factor for non-small cell lung cancer. However, the clinical significance of postsurgical skeletal muscle loss remains unclear. We investigated the impact of a postoperative decrease in pectoralis major muscle mass on long-term outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective evaluation was conducted on 460 patients with pathological stage I\u2013II non-small cell lung cancer who underwent lobectomy. Patients were categorized into two groups based on whether they did or did not show a decrease in pectoralis major muscle mass 12\u00a0months postoperatively, using a muscle mass change rate of 0.94 as the cutoff.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The group showing a decrease in muscle mass (n\u00a0=\u00a0126) exhibited a higher incidence of chronic obstructive pulmonary disease than the group showing no decrease in muscle mass (n\u00a0=\u00a0334). The median rate of change in the muscle mass of the pectoralis major was 1.00. The median follow-up period was 42.8\u00a0months. Overall survival was significantly lower in the group showing a decrease in muscle mass than in the group showing no decrease in muscle mass (P\u00a0&amp;lt;\u00a0.001). Multivariable Cox regression analysis revealed that a decrease in pectoralis major muscle mass after surgery was an independent prognostic factor for overall survival (hazard ratio, 1.05; 95% confidence interval, 1.03\u20131.06; P\u00a0&amp;lt;\u00a0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>A decrease in pectoralis major muscle mass following lobectomy is associated with poor prognosis in patients with non-small cell lung cancer.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jjco\/hyaf072","type":"journal-article","created":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T12:32:38Z","timestamp":1746361958000},"page":"941-946","source":"Crossref","is-referenced-by-count":1,"title":["Impact of pectoralis major muscle mass decrease after lobectomy on the prognosis of lung cancer"],"prefix":"10.1093","volume":"55","author":[{"given":"Risa","family":"Kuboi","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology, Hiroshima University , 1-2-3 Kasumi, Minami Ward, Hiroshima City, Hiroshima 734-8551 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norifumi","family":"Tsubokawa","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Hiroshima University , 1-2-3 Kasumi, Minami Ward, Hiroshima City, Hiroshima 734-8551 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Kamigaichi","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Hiroshima University , 1-2-3 Kasumi, Minami Ward, Hiroshima City, Hiroshima 734-8551 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobutaka","family":"Kawamoto","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Hiroshima University , 1-2-3 Kasumi, Minami Ward, Hiroshima City, Hiroshima 734-8551 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Mimae","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Hiroshima University , 1-2-3 Kasumi, Minami Ward, Hiroshima City, Hiroshima 734-8551 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Miyata","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Hiroshima University , 1-2-3 Kasumi, Minami Ward, Hiroshima City, Hiroshima 734-8551 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morihito","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Hiroshima University , 1-2-3 Kasumi, Minami Ward, Hiroshima City, Hiroshima 734-8551 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