{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T18:17:45Z","timestamp":1757614665637,"version":"3.44.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Several studies have reported the pattern of lymph node (LN) metastasis in patients undergoing segmentectomy for non-small cell lung cancer (NSCLC) &amp;lt;2\u00a0cm. However, the pattern of LN metastasis in cases of NSCLC &amp;gt;2\u20133\u00a0cm remains unknown.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This retrospective study reviewed the clinicopathological features of 406 consecutive patients with NSCLC (\u22643\u00a0cm, cN0) who underwent segmentectomy or lobectomy between January 2017 and December 2023. The tumours were classified into part-solid tumours \u22642\u00a0cm (Group A, n\u00a0=\u00a080), pure-solid tumours \u22642\u00a0cm (Group B, n\u00a0=\u00a072), part-solid tumours &amp;gt;2\u20133\u00a0cm (Group C, n\u00a0=\u00a0140), and pure-solid tumours &amp;gt;2\u20133\u00a0cm (Group D, n\u00a0=\u00a0113). Patterns of LN metastasis, recurrence, and pathological invasive factors were compared amongst the four groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The number of patients with pN1\/pN2a\/pN2b in Groups A, B, C, and D were 0\/1\/0, 4\/0\/0, 5\/6\/1, and 9\/2\/3, respectively. There was no difference in the pathological invasive factors between Groups A and B. No patient with part-solid tumours had non-adjacent interlobar LN metastasis or hilar or mediastinal LN recurrence. Group D (37.2%) had more lymphatic invasion than Group C (25.0%) (P\u00a0=\u00a00.040). One patient with a pure-solid tumour had non-adjacent interlobar LN metastasis. None of the patients with part-solid tumours in the upper lobe experienced recurrence outside the region of selective LN dissection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Non-adjacent interlobar or mediastinal lymph node dissection may be omitted for pure-solid tumours even if indicated segmentectomy for NSCLC &amp;gt;2\u20133\u00a0cm. Selective LN dissection is adequate for patients with pure-solid upper lobe tumours &amp;gt;2\u20133\u00a0cm.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jjco\/hyaf097","type":"journal-article","created":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T07:16:42Z","timestamp":1748071002000},"page":"1073-1079","source":"Crossref","is-referenced-by-count":0,"title":["The pattern of lymph node metastasis in patients with peripheral non-small cell lung cancer &amp;gt;2\u20133\u00a0cm"],"prefix":"10.1093","volume":"55","author":[{"given":"Tomohiro","family":"Maniwa","sequence":"first","affiliation":[{"name":"Department of General Thoracic Surgery, Osaka International Cancer Institute , Osaka ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisaya","family":"Chikaraishi","sequence":"additional","affiliation":[{"name":"Department of General Thoracic Surgery, Osaka International Cancer Institute , Osaka 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