{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:17:05Z","timestamp":1791764225699,"version":"4.3.4"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Psychoeducational and relaxation-based interventions have been shown to reduce caregiver burden; however, limited evidence exists regarding the effectiveness of combined interventions delivered via mobile health (mHealth) in resource-limited settings. This study aimed to evaluate the combined effects of mHealth-based psychoeducation and the Benson Relaxation Technique (BRT) on caregiver burden among female informal caregivers of patients with cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective, open-ended, randomized controlled trial (1:1 allocation) was conducted from October 2024 to March 2025. In total, 102 female caregivers were randomly assigned to either the intervention or control group. Validated Bangla versions of the Zarit Burden Interview, Hospital Anxiety and Depression Scale, and WHO \u2013 Quality of Life \u2013 Brief (WHOQOL-BREF) were administered at baseline, three months, and six months. Data were analyzed using repeated-measures analysis of variance under the intention-to-treat principle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The intervention group demonstrated significant reductions in caregiver burden (F\u00a0=\u00a058.4, P\u00a0&amp;lt;\u00a0.001), anxiety (F\u00a0=\u00a034.9, P\u00a0&amp;lt;\u00a0.001), and depression (F\u00a0=\u00a034.9, P\u00a0&amp;lt;\u00a0.001) over six months, compared to the control group. Significant group \u00d7 time interactions were observed for overall quality of life (QOL) (P\u00a0&amp;lt;\u00a0.001) and across physical (P\u00a0&amp;lt;\u00a0.001), psychological (P\u00a0&amp;lt;\u00a0.001), social (P\u00a0=\u00a0.004), and environmental (P\u00a0&amp;lt;\u00a0.001) domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The combined mHealth psychoeducation and BRT intervention significantly reduced caregiver burden and psychological distress, and improved QOL among female caregivers of patients with cancer. This culturally adaptable, low-cost, technology-enabled approach offers a promising strategy to support caregiver needs in low- and middle-income countries where psychosocial services are limited.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jjco\/hyag026","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T12:07:55Z","timestamp":1769515675000},"page":"748-756","source":"Crossref","is-referenced-by-count":1,"title":["Combined effects of mobile health (mHealth) psychoeducation and the Benson relaxation technique on caregiving burden among female caregivers of patients with cancer: a randomized controlled trial"],"prefix":"10.1093","volume":"56","author":[{"given":"Md Marufur","family":"Roshid","sequence":"first","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences, Hiroshima University , 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8553 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Moshiur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences, Hiroshima University , 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8553 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaniz Fateema","family":"Eity","sequence":"additional","affiliation":[{"name":"Department of Health and Human Performance, East Texas A&M University , 2600 South Neal Street Commerce, TX 75428 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5629-9342","authenticated-orcid":false,"given":"Hitoshi","family":"Okamura","sequence":"additional","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences, Hiroshima University , 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8553 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"key":"2026060515385340500_ref1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"2026060515385340500_ref2","doi-asserted-by":"publisher","first-page":"e2443198","DOI":"10.1001\/jamanetworkopen.2024.43198","article-title":"Global disparities of cancer and its projected burden in 2050","volume":"7","author":"Bizuayehu","year":"2024","journal-title":"JAMA Netw Open"},{"key":"2026060515385340500_ref3","volume-title":"PDQ cancer information summaries","author":"PDQ Supportive and Palliative Care Editorial Board, eds","year":"2025"},{"key":"2026060515385340500_ref4","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1186\/s12913-024-11191-w","article-title":"Gender differences in family caregiving. 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