{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T15:20:29Z","timestamp":1785943229581,"version":"3.56.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate whether there are differences in treatment approaches, including complications according to the volume of treatment experience for penile cancer, and whether such differences affect patient prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 196 patients with penile cancer treated at 12 university hospitals and affiliated institutions (total of 32 institutions) in the Kyushu-Okinawa region from 2009 to 2020. Cancer-specific survival (CSS) was compared between patients treated at lower-volume centers (defined as institutions with fewer than five cases during the study period) and higher-volume centers (five or more cases). The underlying factors contributing to differences in CSS were also analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Groups treated at lower-volume and higher-volume centers comprised 39 and 157 patients, respectively. No significant differences were observed in patient backgrounds. However, among patients with clinical stage 3 disease, CSS was significantly worse in the lower-volume center group. In that subgroup, significantly fewer patients underwent lymph node dissection. There were no notable differences in other treatments or complications between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A disparity in CSS was observed specifically in patients with clinical stage 3 disease. The lower rate of lymph node dissection in lower-volume centers appears to be a contributing factor to the inferior prognosis in this group. No other differences were found in treatment or complication rates, suggesting that lower-volume centers can deliver care that is comparable to that in higher-volume centers, apart from lymph node dissection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jjco\/hyag070","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T11:42:49Z","timestamp":1776253369000},"page":"1007-1014","source":"Crossref","is-referenced-by-count":0,"title":["Impact of treatment volume on outcomes for patients with penile cancer at relatively low-volume centers in Japan"],"prefix":"10.1093","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5176-0441","authenticated-orcid":false,"given":"Yoji","family":"Murakami","sequence":"first","affiliation":[{"name":"Department of Urology, Faculty of Life Sciences, Kumamoto University , 1-1-1 Honjo, Chuo-ku, Kumamoto, Kumamoto 860-8556,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0985-7305","authenticated-orcid":false,"given":"Takahiro","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Urology, Kumamoto Kenhoku Hospital , 550 Tamana, Tamana, Kumamoto 865-0005,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Goya","sequence":"additional","affiliation":[{"name":"Department of Urology, Chubu Tokushukai Hospital , 801 Higa, Kitanakagusuku, Nakagami, Okinawa 901-2393 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuyoshi","family":"Higashijima","sequence":"additional","affiliation":[{"name":"Department of Urology, School of Medicine University of Occupational and Environmental Health , 1-1 Ishiyama-ga-oka, Yahatanishi-ku, Kitakyushu, Fukuoka 807-8556 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohei","family":"Tobu","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Saga University , 1-1-5, Nabeshima, Saga, Saga 849-8501 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Urology, Beppu Medical Center , 1473 Kamado, Beppu, Oita 874-0011 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichi","family":"Tatarano","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Kagoshima University , 10-1 Kamoike Shinmachi, Kagoshima, Kagoshima 890-8577 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichiro","family":"Mukai","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, University of Miyazaki , 5200 Kihara, Kiyotake-cho, Miyazaki, Miyazaki 889-1692 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei-Ichiro","family":"Uemura","sequence":"additional","affiliation":[{"name":"Department of Urology, Kurume University School of Medicine , 67 Asahi-machi, Kurume, Fukuoka 830-0011 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsunori","family":"Tatsugami","sequence":"additional","affiliation":[{"name":"Department of Urology, Kitakyushu Municipal Medical Center , 2-1-1 Umakari, Kokurakita-ku, Kitakyushu, Fukuoka 802-8561 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuna","family":"Tsubouchi","sequence":"additional","affiliation":[{"name":"Department of Urology, Chihaya Urological Clinic , 34-28-2 Chihaya, Higashi-ku, Fukuoka, Fukuoka 813-0044 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Shida","sequence":"additional","affiliation":[{"name":"Department of Urology, Shida Urological Clinic , 44-8 Onoe-machi, Nagasaki, Nagasaki 850-0058 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsu","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Urology, Fukuoka University Chikushi Hospital , 1-1-1 Sokumei-in, Chikushino, Fukuoka 818-8502 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Urology, Nagasaki University Graduate School of Biomedical Sciences , 1-7-1 Sakamoto, Nagasaki, Nagasaki 852-8501 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Matsuoka","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Fukuoka University , 1-45-7 Nanakuma, Jonan-ku, Fukuoka, Fukuoka 814-0180 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiro","family":"Haga","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Fukuoka University , 1-45-7 Nanakuma, Jonan-ku, Fukuoka, Fukuoka 814-0180 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"Eto","sequence":"additional","affiliation":[{"name":"Department of Urology, Graduate School of Medical Sciences, Kyushu University , 1-1-3 Maidashi, Higashi-ku, Fukuoka, Fukuoka 812-8582 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsukasa","family":"Igawa","sequence":"additional","affiliation":[{"name":"Department of Urology, Kurume University School of Medicine , 67 Asahi-machi, Kurume, Fukuoka 830-0011 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Kamoto","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, University of Miyazaki , 5200 Kihara, Kiyotake-cho, Miyazaki, Miyazaki 889-1692 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Enokida","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Kagoshima University , 10-1 Kamoike Shinmachi, Kagoshima, Kagoshima 890-8577 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshitaka","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Oita University , 1-1 Idaigaoka, Hasamamachi, Yufu, Oita 879-5593 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