{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T06:10:31Z","timestamp":1707977431579},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,5,1]]},"DOI":"10.1093\/jjco\/hym040","type":"journal-article","created":{"date-parts":[[2007,6,22]],"date-time":"2007-06-22T00:48:41Z","timestamp":1182473321000},"page":"345-352","source":"Crossref","is-referenced-by-count":8,"title":["Accelerated Radiotherapy and Larynx Preservation in Favorable-risk Patients with T2 or Worse Hypopharyngeal Cancer"],"prefix":"10.1093","volume":"37","author":[{"given":"Mitsuhiko","family":"Kawashima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuichi","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Tahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuo","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoko","family":"Arahira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Ogino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2007,6,21]]},"reference":[{"key":"key\n\t\t\t\t20171013023200_HYM040C1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1288\/00005537-198204000-00001","article-title":"Squamous cell carcinoma of the pyriform sinus","volume":"92","author":"El badawi","year":"1982","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20171013023200_HYM040C2","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1148\/radiology.160.3.3737924","article-title":"Cancer of the pyriform sinus: treatment by radiation therapy alone and with surgery","volume":"160","author":"Dubois","year":"1986","journal-title":"Radiology"},{"key":"key\n\t\t\t\t20171013023200_HYM040C3","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1288\/00005537-198708000-00002","article-title":"Treatment of hypopharyngeal carcinoma: a 10-year review of 1362 cases","volume":"97","author":"Pingree","year":"1987","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20171013023200_HYM040C4","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/hed.2890100103","article-title":"Squamous cell carcinoma of the pyriform sinus: retrospective study of 351 cases treated at the Institut Gustave-Roussy","volume":"10","author":"Vandenbrouck","year":"1987","journal-title":"Head Neck Surg"},{"key":"key\n\t\t\t\t20171013023200_HYM040C5","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/hed.2890100205","article-title":"Squamous cell carcinoma of the pyriform sinus treated with surgery and\/or radiotherapy","volume":"10","author":"Mendenhall","year":"1987","journal-title":"Head Neck Surg"},{"key":"key\n\t\t\t\t20171013023200_HYM040C6","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0194-5998(97)70240-7","article-title":"Combined surgery and radiation therapy for squamous cell carcinoma of the hypopharynx","volume":"116","author":"Kraus","year":"1997","journal-title":"Otolaryngol Head Neck Surg"},{"key":"key\n\t\t\t\t20171013023200_HYM040C7","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1067\/mhn.2001.115060","article-title":"Surgical treatment for hypopharynx carcinoma: feasibility, mortality, and results","volume":"124","author":"Eckel","year":"2001","journal-title":"Otolaryngol Head Neck Surg"},{"key":"key\n\t\t\t\t20171013023200_HYM040C8","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1093\/jnci\/88.13.890","article-title":"Larynx preservation in pyriform sinus cancer: preliminary results of European Organization for Research and Treatment of Cancer phase III trial","volume":"88","author":"Lefebvre","year":"1996","journal-title":"J Natl Cancer Inst"},{"key":"key\n\t\t\t\t20171013023200_HYM040C9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1001\/archotol.1995.01890020081015","article-title":"Laryngeal preservation for advanced laryngeal and hypopharyngeal cancers","volume":"121","author":"Clayman","year":"1995","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"key\n\t\t\t\t20171013023200_HYM040C10","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s10147-004-0445-x","article-title":"Chemoradiotherapy for head and neck cancer: current status and perspectives","volume":"9","author":"Kawashima","year":"2004","journal-title":"Int J Clin Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C11","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0360-3016(83)90231-6","article-title":"Carcinoma of the hypopharynx results of primary radical radiation therapy","volume":"9","author":"Kaene","year":"1983","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C12","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1288\/00005537-198103000-00015","article-title":"Radical irradiation for carcinoma of the pyriform sinus","volume":"91","author":"Million","year":"1981","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20171013023200_HYM040C13","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/0360-3016(82)90576-4","article-title":"Results of radical radiotherapeutic treatment of carcinoma of the pyriform sinus: experience of the Institut Curie","volume":"8","author":"Bataini","year":"1982","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C14","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3109\/02841868409135980","article-title":"Role of radiation therapy in carcinoma of the hypopharynx","volume":"23","author":"Ahmad","year":"1984","journal-title":"Acta Radiologica Oncology"},{"key":"key\n\t\t\t\t20171013023200_HYM040C15","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0167-8140(85)80044-X","article-title":"Hypopharyngeal cancer: results of treatment with radiotherapy alone and combinations of surgery and radiotherapy","volume":"3","author":"Van den Bogaert","year":"1985","journal-title":"Radiother Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C16","doi-asserted-by":"crossref","first-page":"903","DOI":"10.3109\/02841869009096387","article-title":"Carcinoma of the hypopharynx: a retrospective analysis of the treatment results over a 25-year period","volume":"29","author":"Kajanti","year":"1990","journal-title":"Acta Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/019459989411100108","article-title":"Larynx preservation with combined chemotherapy and radiation therapy in advanced hypopharynx cancer","volume":"111","author":"Kraus","year":"1994","journal-title":"Otolaryngol Head Neck Surg"},{"key":"key\n\t\t\t\t20171013023200_HYM040C18","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/(SICI)1097-0347(199607\/08)18:4<317::AID-HED2>3.0.CO;2-0","article-title":"Early squamous cell carcinoma of the hypopharynx: outcomes of treatment with radiation alone to the primary disease","volume":"18","author":"Garden","year":"1996","journal-title":"Head Neck"},{"key":"key\n\t\t\t\t20171013023200_HYM040C19","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1097\/00005537-199705000-00017","article-title":"Final results of a randomized trial comparing chemotherapy plus radiotherapy with chemotherapy plus surgery plus radiotherapy in locally advanced resectable hypopharyngeal carcinomas","volume":"107","author":"Beauvillain","year":"1997","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20171013023200_HYM040C20","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1080\/028418600750013465","article-title":"Hypopharyngeal squamous cell carcinoma: treatment results in 138 consecutively admitted patients","volume":"39","author":"Johansen","year":"2000","journal-title":"Acta Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C21","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/hed.1044","article-title":"Organ preservation with radiotherapy for T1-T2 carcinoma of the pyriform sinus","volume":"23","author":"Amdur","year":"2001","journal-title":"Head Neck"},{"key":"key\n\t\t\t\t20171013023200_HYM040C22","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/00005537-200205000-00011","article-title":"Hypopharyngeal cancer: results of treatment based on radiation therapy and salvage surgery","volume":"112","author":"Godballe","year":"2002","journal-title":"Laryngoscope"},{"key":"key\n\t\t\t\t20171013023200_HYM040C23","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0360-3016(00)00663-5","article-title":"A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: First report of RTOG 9003","volume":"48","author":"Fu","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C24","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1056\/NEJMoa031317","article-title":"Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer","volume":"349","author":"Forastiere","year":"2003","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20171013023200_HYM040C25","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0140-6736(03)14361-9","article-title":"Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6&7 randomized controlled trial","volume":"362","author":"Overgaard","year":"2003","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20171013023200_HYM040C26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0167-8140(92)90242-M","article-title":"Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy","volume":"25","author":"Horiot","year":"1992","journal-title":"Radiother Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C27","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/jnci\/88.9.583","article-title":"Five-year update of randomized trial of alternating radiotherapy and chemotherapy compared with radiotherapy alone in treatment of unresectable squamous cell carcinoma of the head and neck","volume":"88","author":"Merlano","year":"1996","journal-title":"J Natl Cancer Inst"},{"key":"key\n\t\t\t\t20171013023200_HYM040C28","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1200\/JCO.1998.16.4.1318","article-title":"Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study","volume":"16","author":"Wendt","year":"1998","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C29","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1056\/NEJM199806183382503","article-title":"Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer","volume":"338","author":"Britzel","year":"1998","journal-title":"N Engl J Med."},{"key":"key\n\t\t\t\t20171013023200_HYM040C30","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1200\/JCO.2000.18.7.1458","article-title":"Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial","volume":"18","author":"Jeremic","year":"2000","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C31","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1200\/JCO.2003.01.008","article-title":"An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer","volume":"21","author":"Adelstein","year":"2003","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C32","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/S0360-3016(01)01544-9","article-title":"Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy\u2015results of a multicentric randomized German trial in advanced head and neck cancer","volume":"50","author":"Staar","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C33","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1200\/JCO.2004.08.021","article-title":"Final results of the French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma","volume":"22","author":"Denis","year":"2004","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C34","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0360-3016(90)90054-N","article-title":"Dose\u2013response for local control with hyperfractionated radiation therapyin advanced carcinomas of the upper aerodigestive tracts: preliminary report of Radiation Therapy Oncology Group protocol 83-13","volume":"18","author":"Cox","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C35","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0167-8140(01)00429-7","article-title":"Consequential late effects in normal tissues","volume":"61","author":"D\u00f6rr","year":"2001","journal-title":"Radiother Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C36","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.ijrobp.2004.11.012","article-title":"Chemoradiation therapy with or without salvage surgery for early squamous cell carcinoma of the hypopharynx","volume":"62","author":"Nakamura","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C37","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.ijrobp.2006.02.001","article-title":"Multi-institutional analysis of early squamous cell carcinoma of the hypopharynx treated with radical radiotherapy","volume":"65","author":"Nakamura","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C38","first-page":"11","article-title":"Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer","volume":"547s","author":"Okamoto","year":"5002","journal-title":"Acta Otolaryngol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C39","first-page":"31","volume-title":"In American Joint Committee on Cancer: AJCC Cancer Staging Manual","author":"Pharynx (including base of tongue soft palate uvula)","year":"2002","edition":"6th edn"},{"key":"key\n\t\t\t\t20171013023200_HYM040C40","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/jjco\/29.10.467","article-title":"Local-regional control by conventional radiotherapy according to tumor volume in patients with squamous cell carcinoma of the pharyngolarynx","volume":"29","author":"Kawashima","year":"1999","journal-title":"Jpn J Clin Oncol"},{"key":"key\n\t\t\t\t20171013023200_HYM040C41","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.ijrobp.2005.09.041","article-title":"French multicenter phase III randomized study testing concurrent twice-a-day radiotherapy and cisplatin\/5-fluorouracil chemotherapy (BiRCF) in unresectable pharyngeal carcinoma: results at 2 years (FNCLCC-GORTEC)","volume":"64","author":"Bensadoun","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C42","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S0140-6736(00)90011-4","article-title":"Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data","volume":"355","author":"Pignon","year":"2000","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20171013023200_HYM040C43","article-title":"Update of MACH-NC (meta-analysis of chemotherapy in head & neck cancer) database focused on concomitant chemoradiotherapy","author":"Bourhis","year":"2004","journal-title":"Proc ASCO"},{"key":"key\n\t\t\t\t20171013023200_HYM040C44","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0360-3016(99)00438-1","article-title":"Radiobiological considerations in the design of fractionation strategies for intensity-modulated radiation therapy of head and neck cancers","volume":"46","author":"Mohan","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key\n\t\t\t\t20171013023200_HYM040C45","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.ijrobp.2005.02.045","article-title":"Matched case-control study of quality of life and xerostomia after intensity-modulated radiotherapy or standard radiotherapy for head and neck cancer: initial report","volume":"63","author":"Jabbari","year":"2005","journal-title":"Int J Radiation Oncology Biol Phys"}],"container-title":["Japanese Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jjco\/article-pdf\/37\/5\/345\/5429835\/hym040.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T05:41:25Z","timestamp":1707975685000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/jjco\/article\/37\/5\/345\/941703\/Accelerated-Radiotherapy-and-Larynx-Preservation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,1]]},"references-count":45,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2007,6,21]]},"published-print":{"date-parts":[[2007,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jjco\/hym040","relation":{},"ISSN":["1465-3621","0368-2811"],"issn-type":[{"value":"1465-3621","type":"electronic"},{"value":"0368-2811","type":"print"}],"subject":[],"published-other":{"date-parts":[[2007,5]]},"published":{"date-parts":[[2007,5,1]]}}}