{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T21:12:02Z","timestamp":1760044322869,"version":"3.37.3"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"12","funder":[{"name":"The National Cancer Center Research and Development Fund","award":["25-A-1"],"award-info":[{"award-number":["25-A-1"]}]},{"name":"Practical Research for Innovative Cancer Control"},{"name":"Promoting Practical Applications of Genomic Medicine"},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["15ck0106097 h0102 and 15cK0106168 h0201"],"award-info":[{"award-number":["15ck0106097 h0102 and 15cK0106168 h0201"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,12,1]]},"DOI":"10.1093\/jjco\/hyx132","type":"journal-article","created":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T07:08:59Z","timestamp":1503644939000},"page":"1193-1197","source":"Crossref","is-referenced-by-count":3,"title":["Cardiac paraganglioma with a novel germline mutation of succinate dehydrogenase gene D"],"prefix":"10.1093","volume":"47","author":[{"given":"Naoyuki","family":"Otani","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kokichi","family":"Sugano","sequence":"additional","affiliation":[{"name":"Oncogene Res Unit\/Cancer Prevention Unit, Tochigi Cancer Center Research Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu","family":"Inami","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohisa","family":"Amano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuo","family":"Arikawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Saito","sequence":"additional","affiliation":[{"name":"Oncogene Res Unit\/Cancer Prevention Unit, Tochigi Cancer Center Research Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuho","family":"Imai","sequence":"additional","affiliation":[{"name":"Oncogene Res Unit\/Cancer Prevention Unit, Tochigi Cancer Center Research Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mineko","family":"Ushiama","sequence":"additional","affiliation":[{"name":"Division of Genetics, National Cancer Center Research Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruhiko","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Genetic Medicine and Services, National Cancer Center Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Pathology Section, National Hospital Organization, Hakodate Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Toyoda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruo","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Dokkyo Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,9,18]]},"reference":[{"key":"key\n\t\t\t\t20180328175214_hyx132C1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S0140-6736(05)67139-5","article-title":"Phaeochromocytoma","volume":"36","author":"Lenders","year":"2005","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180328175214_hyx132C2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.2214\/ajr.168.1.8976931","article-title":"Intrapericardial paragangliomas (pheochromocytomas): imaging features","volume":"168","author":"Hamilton","year":"1997","journal-title":"AJR Am J Roentgenol"},{"key":"key\n\t\t\t\t20180328175214_hyx132C3","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.carpath.2009.07.005","article-title":"Pathological study of primary cardiac and pericardial tumours in a specialist UK Centre: surgical and autopsy series","volume":"19","author":"Patel","year":"2010","journal-title":"Cardiovasc Pathol"},{"key":"key\n\t\t\t\t20180328175214_hyx132C4","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jacc.2011.05.027","article-title":"Characterization of cardiac tumors in children by cardiovascular magnetic resonance imaging: a multicenter experience","volume":"58","author":"Beroukhim","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180328175214_hyx132C5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1086\/321282","article-title":"Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma","volume":"69","author":"Astuti","year":"2001","journal-title":"Am J Hum Genet"},{"key":"key\n\t\t\t\t20180328175214_hyx132C6","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1056\/NEJMc1012357","article-title":"Renal tumors and hereditary pheochromocytoma-paraganglioma syndrome type 4","volume":"364","author":"Gill","year":"2011","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180328175214_hyx132C7","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1002\/humu.10212","article-title":"Human Gene Mutation Database (HGMD): 2003 update","volume":"21","author":"Stenson","year":"2003","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20180328175214_hyx132C8","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nmeth0410-248","article-title":"A method and server for predicting damaging missense mutations","volume":"7","author":"Adzhubei","year":"2010","journal-title":"Nat Methods"},{"key":"key\n\t\t\t\t20180328175214_hyx132C9","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1126\/science.287.5454.848","article-title":"Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma","volume":"287","author":"Baysal","year":"2000","journal-title":"Science"},{"key":"key\n\t\t\t\t20180328175214_hyx132C10","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1507\/endocrj.K09E-324","article-title":"A large deletion in the succinate dehydrogenase B gene (SDHB) in a Japanese patient with abdominal paraganglioma and concomitant metastasis","volume":"57","author":"Kodama","year":"2010","journal-title":"Endocr J"},{"key":"key\n\t\t\t\t20180328175214_hyx132C11","doi-asserted-by":"crossref","first-page":"T91","DOI":"10.1530\/ERC-15-0268","article-title":"15 YEARS OF PARAGANGLIOMA: clinical manifestations of paraganglioma syndromes types 1-5","volume":"22","author":"Benn","year":"2015","journal-title":"Endocr Relat Cancer"},{"key":"key\n\t\t\t\t20180328175214_hyx132C12","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/humu.21136","article-title":"Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD","volume":"31","author":"Ricketts","year":"2010","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20180328175214_hyx132C13","doi-asserted-by":"crossref","first-page":"e241","DOI":"10.1371\/journal.pcbi.0030241","article-title":"Stereochemical criteria for prediction of the effects of proline mutations on protein stability","volume":"3","author":"Bajaj","year":"2007","journal-title":"PLoS Comput Biol"},{"key":"key\n\t\t\t\t20180328175214_hyx132C14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s13205-012-0088-y","article-title":"Leucine to proline substitution by SNP at position 197 in Caspase-9 gene expression leads to neuroblastoma: a bioinformatics analysis","volume":"3","author":"Kundu","year":"2013","journal-title":"3 Biotech"},{"key":"key\n\t\t\t\t20180328175214_hyx132C15","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1001\/jama.292.8.943","article-title":"Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations","volume":"292","author":"Neumann","year":"2004","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20180328175214_hyx132C16","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1210\/jc.2005-1862","article-title":"Clinical presentation and penetrance of pheochromocytoma\/paraganglioma syndromes","volume":"91","author":"Benn","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20180328175214_hyx132C17","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/S0140-6736(89)91908-9","article-title":"Genomic imprinting in hereditary glomus tumours: evidence for new genetic theory","volume":"2","author":"Van der Mey","year":"1989","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180328175214_hyx132C18","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1038\/modpathol.2015.41","article-title":"SDHB\/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T)","volume":"28","author":"Papathomas","year":"2015","journal-title":"Mod Pathol"},{"key":"key\n\t\t\t\t20180328175214_hyx132C19","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1530\/ERC-13-0494","article-title":"Pathological grading for predicting metastasis in phaeochromocytoma and paraganglioma","volume":"21","author":"Kimura","year":"2014","journal-title":"Endocr Relat Cancer"}],"container-title":["Japanese Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jjco\/article-pdf\/47\/12\/1193\/22315717\/hyx132.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T03:08:33Z","timestamp":1522292913000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jjco\/article\/47\/12\/1193\/4160408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,18]]},"references-count":19,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2017,9,18]]},"published-print":{"date-parts":[[2017,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jjco\/hyx132","relation":{},"ISSN":["0368-2811","1465-3621"],"issn-type":[{"type":"print","value":"0368-2811"},{"type":"electronic","value":"1465-3621"}],"subject":[],"published-other":{"date-parts":[[2017,12]]},"published":{"date-parts":[[2017,9,18]]}}}