{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:57:25Z","timestamp":1777906645012,"version":"3.51.4"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81402201"],"award-info":[{"award-number":["81402201"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81372817"],"award-info":[{"award-number":["81372817"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Natural Science Foundation of Guangdong Province","award":["2014A030310070"],"award-info":[{"award-number":["2014A030310070"]}]},{"name":"National Natural Science Foundation of Guangdong Province","award":["163"],"award-info":[{"award-number":["163"]}]},{"name":"Key Laboratory of Malignant Tumor Molecular Mechanism"},{"name":"Translational Medicine of the Guangzhou Bureau of Science and Information Technology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,1,1]]},"DOI":"10.1093\/jjco\/hyy181","type":"journal-article","created":{"date-parts":[[2018,11,15]],"date-time":"2018-11-15T16:36:32Z","timestamp":1542299792000},"page":"22-28","source":"Crossref","is-referenced-by-count":10,"title":["Development and validation of a nomogram incorporating axillary lymph node ratio to predict survival in node-positive breast cancer patients after neoadjuvant chemotherapy"],"prefix":"10.1093","volume":"49","author":[{"given":"Jianguo","family":"Lai","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"},{"name":"Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zihao","family":"Pan","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"},{"name":"Department of Thoracic Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peixian","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Breast Oncology, Cancer Center, First People\u2019s Hospital of Foshan (Affiliated Foshan Hospital of Sun Yat-Sen University), Foshan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guolin","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Breast Oncology, Cancer Center, First People\u2019s Hospital of Foshan (Affiliated Foshan Hospital of Sun Yat-Sen University), Foshan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Chen","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"},{"name":"Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengxi","family":"Su","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"},{"name":"Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,12,1]]},"reference":[{"key":"key\n\t\t\t\t2019012104285467200_hyy181C1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3322\/caac.21338","article-title":"Cancer statistics in China, 2015","volume":"66","author":"Chen","year":"2016","journal-title":"CA Cancer J Clin"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C2","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1158\/1078-0432.CCR-03-0133","article-title":"Evidence-based use of neoadjuvant taxane in operable and inoperable breast cancer","volume":"10","author":"Estevez","year":"2004","journal-title":"Clin Cancer Res"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C3","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1200\/JCO.2003.01.136","article-title":"International expert panel on the use of primary (preoperative) systemic treatment of operable breast cancer: review and recommendations","volume":"21","author":"Kaufmann","year":"2003","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C4","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1200\/JCO.2005.04.1665","article-title":"Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer:National Surgical Adjuvant Breast and Bowel Project Protocol B-27","volume":"24","author":"Bear","year":"2006","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C5","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S0140-6736(13)62422-8","article-title":"Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis","volume":"384","author":"Cortazar","year":"2014","journal-title":"Lancet"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C6","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/1097-0142(19890101)63:1<181::AID-CNCR2820630129>3.0.CO;2-H","article-title":"Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases","volume":"63","author":"Carter","year":"1989","journal-title":"Cancer"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C7","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1245\/s10434-013-3308-8","article-title":"The number of lymph nodes dissected in breast cancer patients influences the accuracy of prognosis","volume":"21","author":"Wiznia","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C8","doi-asserted-by":"crossref","first-page":"757","DOI":"10.4143\/crt.2014.039","article-title":"Using the lymph node ratio to evaluate the prognosis of stage ii\/iii breast cancer patients who received neoadjuvant chemotherapy and mastectomy","volume":"47","author":"Wu","year":"2015","journal-title":"Cancer Res Treat"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C9","doi-asserted-by":"crossref","first-page":"3310","DOI":"10.1245\/s10434-016-5319-8","article-title":"Lymph node ratio analysis after neoadjuvant chemotherapy is prognostic in hormone receptor-positive and triple-negative breast cancer","volume":"23","author":"Tsai","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C10","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10549-008-0160-9","article-title":"Clinical significance of axillary nodal ratio in stage II\/III breast cancer treated with neoadjuvant chemotherapy. 45","volume":"116","author":"Keam","year":"2009","journal-title":"Breast Cancer Res Treat"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C11","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1245\/s10434-013-3245-6","article-title":"Lymph node counts and ratio in axillary dissections following neoadjuvant chemotherapy for breast cancer: a better alternative to traditional pN staging","volume":"21","author":"Chen","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C12","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/0959-8049(92)90534-9","article-title":"Axillary dissection of level I and II lymph nodes is important in breast cancer classification. The Danish Breast Cancer Cooperative Group (DBCG)","volume":"28a","author":"Axelsson","year":"1992","journal-title":"Eur J Cancer"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C13","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.jamcollsurg.2007.10.016","article-title":"Neoadjuvant chemotherapy in invasive breast cancer results in a lower axillary lymph node count","volume":"206","author":"Belanger","year":"2008","journal-title":"J Am Coll Surg"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C14","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.amjsurg.2005.08.041","article-title":"Axillary lymph node count is lower after neoadjuvant chemotherapy","volume":"191","author":"Neuman","year":"2006","journal-title":"Am J Surg"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C15","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1200\/JCO.1997.15.7.2483","article-title":"Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18","volume":"15","author":"Fisher","year":"1997","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C16","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0002-9610(02)00959-5","article-title":"Decreased axillary lymph node retrieval in patients after neoadjuvant chemotherapy","volume":"184","author":"Baslaim","year":"2002","journal-title":"Am J Surg"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C17","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.2147\/CMAR.S171129","article-title":"Establishment and external validation of a prognostic model for predicting disease-free survival and risk stratification in breast cancer patients treated with neoadjuvant chemotherapy","volume":"10","author":"Lai","year":"2018","journal-title":"Cancer Manag Res"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C18","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1093\/annonc\/mdn747","article-title":"A risk score to predict disease-free survival in patients not achieving a pathological complete remission after preoperative chemotherapy for breast cancer","volume":"20","author":"Colleoni","year":"2009","journal-title":"Ann Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C19","doi-asserted-by":"crossref","first-page":"7252","DOI":"10.1158\/1078-0432.CCR-04-0713","article-title":"X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization","volume":"10","author":"Camp","year":"2004","journal-title":"Clin Cancer Res"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C20","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1200\/JCO.2007.12.9791","article-title":"How to build and interpret a nomogram for cancer prognosis","volume":"26","author":"Iasonos","year":"2008","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C21","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1200\/JCO.2015.65.5654","article-title":"Assessing the clinical impact of risk prediction models with decision curves: guidance for correct interpretation and appropriate use","volume":"34","author":"Kerr","year":"2016","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C22","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1001\/jama.2015.37","article-title":"Decision curve analysis","volume":"313","author":"Fitzgerald","year":"2015","journal-title":"JAMA"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C23","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1177\/0272989X06295361","article-title":"Decision curve analysis: a novel method for evaluating prediction models","volume":"26","author":"Vickers","year":"2006","journal-title":"Med Decis Making"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C24","doi-asserted-by":"crossref","first-page":"i6","DOI":"10.1136\/bmj.i6","article-title":"Net benefit approaches to the evaluation of prediction models, molecular markers, and diagnostic tests","volume":"352","author":"Vickers","year":"2016","journal-title":"BMJ"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C25","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1198\/000313008X370302","article-title":"Decision analysis for the evaluation of diagnostic tests, prediction models and molecular markers","volume":"62","author":"Vickers","year":"2008","journal-title":"Am Stat"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C26","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/1472-6947-8-53","article-title":"Extensions to decision curve analysis, a novel method for evaluating diagnostic tests, prediction models and molecular markers","volume":"8","author":"Vickers","year":"2008","journal-title":"BMC Med Inform Decis Mak"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C27","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1245\/s10434-012-2642-6","article-title":"When is a lymph node dissection a lymph node dissection? The number of lymph nodes resected in sentinel and axillary lymph node dissections","volume":"20","author":"Olaya","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C28","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1136\/jcp.2003.015560","article-title":"Node retrieval in axillary lymph node dissections: recommendations for minimum numbers to be confident about node negative status","volume":"57","author":"Somner","year":"2004","journal-title":"J Clin Pathol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C29","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/jso.20061","article-title":"Variability in axillary lymph node dissection for breast cancer","volume":"87","author":"Schaapveld","year":"2004","journal-title":"J Surg Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C30","first-page":"407","article-title":"Breast cancer: risk of axillary recurrence in node-negative patients following partial dissection of the axilla","volume":"14","author":"Graversen","year":"1988","journal-title":"Eur J Surg Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C31","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1200\/JCO.2008.18.6965","article-title":"Lymph node ratio as an alternative to pN staging in node-positive breast cancer","volume":"27","author":"Vinh-Hung","year":"2009","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t2019012104285467200_hyy181C32","doi-asserted-by":"crossref","first-page":"e173","DOI":"10.1016\/S1470-2045(14)71116-7","article-title":"Nomograms in oncology: more than meets the eye","volume":"16","author":"Balachandran","year":"2015","journal-title":"Lancet Oncol"}],"container-title":["Japanese Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jjco\/article-pdf\/49\/1\/22\/27565521\/hyy181.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T11:34:47Z","timestamp":1572694487000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jjco\/article\/49\/1\/22\/5224994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,1]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,12,1]]},"published-print":{"date-parts":[[2019,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jjco\/hyy181","relation":{},"ISSN":["1465-3621"],"issn-type":[{"value":"1465-3621","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,1]]},"published":{"date-parts":[[2018,12,1]]}}}