{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:35:08Z","timestamp":1789619708502,"version":"build-2803163510"},"reference-count":232,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,3,4]],"date-time":"2023-03-04T00:00:00Z","timestamp":1677888000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Innate immune cells represent the first line of cellular immunity, comprised of both circulating and tissue-resident natural killer cells and innate lymphoid cells. These innate lymphocytes arise from a common CD34+ progenitor that differentiates into mature natural killer cells and innate lymphoid cells. The successive stages in natural killer cell maturation are characterized by increased lineage restriction and changes to phenotype and function. Mechanisms of human natural killer cell development have not been fully elucidated, especially the role of signals that drive the spatial localization and maturation of natural killer cells. Cytokines, extracellular matrix components, and chemokines provide maturation signals and influence the trafficking of natural killer cell progenitors to peripheral sites of differentiation. Here we present the latest advances in our understanding of natural killer and innate lymphoid cell development in peripheral sites, including secondary lymphoid tissues (i.e. tonsil). Recent work in the field has provided a model for the spatial distribution of natural killer cell and innate lymphoid cell developmental intermediates in tissue and generated further insights into the developmental niche. In support of this model, future studies using multifaceted approaches seek to fully map the developmental trajectory of human natural killer cells and innate lymphoid cells in secondary lymphoid tissues.<\/jats:p>","DOI":"10.1093\/jleuko\/qiad027","type":"journal-article","created":{"date-parts":[[2023,3,4]],"date-time":"2023-03-04T12:48:20Z","timestamp":1677934100000},"page":"487-506","source":"Crossref","is-referenced-by-count":15,"title":["Deciphering the localization and trajectory of human natural killer cell development"],"prefix":"10.1093","volume":"114","author":[{"given":"Everardo","family":"Hegewisch-Solloa","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center , 630 W 168th St. New York, NY 10032 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ansel P","family":"Nalin","sequence":"additional","affiliation":[{"name":"Biomedical Sciences Graduate Program, Medical Scientist Training Program, Comprehensive Cancer Center and The James Cancer Hospital and Solove Research Institute, The Ohio State University , 460 W 10th Ave. Columbus, OH 43210 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aharon G","family":"Freud","sequence":"additional","affiliation":[{"name":"Department of Pathology, Comprehensive Cancer Center and The James Cancer Hospital and Solove Research Institute, The Ohio State University , 460 W 12th Ave. Columbus, OH 43210 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0226-7393","authenticated-orcid":false,"given":"Emily M","family":"Mace","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center , 630 W 168th St. New York, NY 10032 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,3,4]]},"reference":[{"issue":"3","key":"2023102617151662800_qiad027-B1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s12026-015-8664-y","article-title":"Practical NK cell phenotyping and variability in healthy adults","volume":"62","author":"Angelo","year":"2015","journal-title":"Immunol Res"},{"key":"2023102617151662800_qiad027-B2","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2016.00545","article-title":"Genetic causes of human NK cell deficiency and their effect on NK cell subsets","volume":"7","author":"Mace","year":"2016","journal-title":"Front Immunol"},{"issue":"5562","key":"2023102617151662800_qiad027-B3","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1126\/science.1068440","article-title":"Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants","volume":"295","author":"Ruggeri","year":"2002","journal-title":"Science"},{"issue":"21","key":"2023102617151662800_qiad027-B4","doi-asserted-by":"crossref","first-page":"3940","DOI":"10.1200\/JCO.2003.05.013","article-title":"Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma","volume":"21","author":"Weng","year":"2003","journal-title":"J Clin Oncol"},{"issue":"10","key":"2023102617151662800_qiad027-B5","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1002\/1521-4141(2001010)31:10<3016::AID-IMMU3016>3.0.CO;2-J","article-title":"Interleukin-2 enhances the natural killer cell response to Herceptin-coated Her2\/neu-positive breast cancer cells","volume":"31","author":"Carson","year":"2001","journal-title":"Eur J Immunol"},{"issue":"3","key":"2023102617151662800_qiad027-B6","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1182\/blood.V99.3.754","article-title":"Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene","volume":"99","author":"Cartron","year":"2002","journal-title":"Blood"},{"issue":"12","key":"2023102617151662800_qiad027-B7","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1182\/blood-2008-03-077974","article-title":"Graft-versus-leukemia effects of transplatation and donor lymphocytes","volume":"112","author":"Kolb","year":"2008","journal-title":"Blood"},{"issue":"9","key":"2023102617151662800_qiad027-B8","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1038\/ni.3518","article-title":"Targeting natural killer cells in cancer immunotherapy","volume":"17","author":"Guillerey","year":"2016","journal-title":"Nat Immunol"},{"issue":"2","key":"2023102617151662800_qiad027-B9","doi-asserted-by":"crossref","first-page":"e14","DOI":"10.4110\/in.2020.20.e14","article-title":"NK cell-based immunotherapies in cancer","volume":"20","author":"Shin","year":"2020","journal-title":"Immune Netw"},{"issue":"12","key":"2023102617151662800_qiad027-B10","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1007\/s00262-010-0904-3","article-title":"A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer","volume":"59","author":"Iliopoulou","year":"2010","journal-title":"Cancer Immunol Immunother"},{"issue":"8","key":"2023102617151662800_qiad027-B11","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1182\/blood-2004-07-2974","article-title":"Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer","volume":"105","author":"Miller","year":"2005","journal-title":"Blood"},{"issue":"1","key":"2023102617151662800_qiad027-B12","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/00002371-200001000-00018","article-title":"Posttransplant adoptive immunotherapy with activated natural killer cells in patients with metastatic breast cancer","volume":"23","author":"deMagalhaes-Silverman","year":"2000","journal-title":"J Immunother"},{"issue":"24","key":"2023102617151662800_qiad027-B13","doi-asserted-by":"crossref","first-page":"4751","DOI":"10.1182\/blood-2012-04-419283","article-title":"Cytokine activation induces human memory-like NK cells","volume":"120","author":"Romee","year":"2012","journal-title":"Blood"},{"issue":"633","key":"2023102617151662800_qiad027-B14","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abm1375","article-title":"Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia","volume":"14","author":"Berrien-Elliott","year":"2022","journal-title":"Sci Transl Med"},{"issue":"11","key":"2023102617151662800_qiad027-B15","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1182\/blood.2021013972","article-title":"Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant","volume":"139","author":"Bednarski","year":"2022","journal-title":"Blood"},{"issue":"12","key":"2023102617151662800_qiad027-B16","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1158\/2159-8290.CD-20-0312","article-title":"Multidimensional analyses of donor memory-like NK cells reveal new associations with response after adoptive immunotherapy for leukemia","volume":"10","author":"Berrien-Elliott","year":"2020","journal-title":"Cancer Discov"},{"issue":"6","key":"2023102617151662800_qiad027-B17","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1080\/14653240802301872","article-title":"Infusion of the allogeneic cell line NK-92 in patients with advanced renal cell cancer or melanoma: a phase I trial","volume":"10","author":"Arai","year":"2008","journal-title":"Cytotherapy"},{"issue":"12","key":"2023102617151662800_qiad027-B18","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/j.jcyt.2013.06.017","article-title":"Treatment of patients with advanced cancer with the natural killer cell line NK-92","volume":"15","author":"Tonn","year":"2013","journal-title":"Cytotherapy"},{"issue":"4","key":"2023102617151662800_qiad027-B19","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00262-015-1761-x","article-title":"NK-92: an \u2018off-the-shelf therapeutic\u2019 for adoptive natural killer cell-based cancer immunotherapy","volume":"65","author":"Suck","year":"2016","journal-title":"Cancer Immunol Immunother"},{"issue":"51","key":"2023102617151662800_qiad027-B20","doi-asserted-by":"crossref","first-page":"89256","DOI":"10.18632\/oncotarget.19204","article-title":"A phase I trial of NK-92 cells for refractory hematological malignancies relapsing after autologous hematopoietic cell transplantation shows safety and evidence of efficacy","volume":"8","author":"Williams","year":"2017","journal-title":"Oncotarget"},{"key":"2023102617151662800_qiad027-B21","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.561553","article-title":"Umbilical cord blood and iPSC-derived natural killer cells demonstrate key differences in cytotoxic activity and KIR profiles","volume":"11","author":"Goldenson","year":"2020","journal-title":"Front Immunol"},{"issue":"1","key":"2023102617151662800_qiad027-B22","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/stem.2230","article-title":"Induced pluripotent stem cell-derived natural killer cells for treatment of ovarian cancer","volume":"34","author":"Hermanson","year":"2016","journal-title":"Stem Cells"},{"issue":"1","key":"2023102617151662800_qiad027-B23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s00281-018-0721-x","article-title":"Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells","volume":"41","author":"Saetersmoen","year":"2019","journal-title":"Semin Immunopathol"},{"issue":"6","key":"2023102617151662800_qiad027-B24","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1016\/j.stemcr.2017.10.020","article-title":"Generation of \u201coff-the-shelf\u201d natural killer cells from peripheral blood cell-derived induced pluripotent stem cells","volume":"9","author":"Zeng","year":"2017","journal-title":"Stem Cell Rep"},{"issue":"8","key":"2023102617151662800_qiad027-B25","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1016\/j.ymthe.2017.06.012","article-title":"Engineering natural killer cells for cancer immunotherapy","volume":"25","author":"Rezvani","year":"2017","journal-title":"Mol Ther"},{"key":"2023102617151662800_qiad027-B26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.canlet.2019.11.033","article-title":"CAR-NK for tumor immunotherapy: clinical transformation and future prospects","volume":"472","author":"Wang","year":"2020","journal-title":"Cancer Lett"},{"key":"2023102617151662800_qiad027-B27","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102975","article-title":"CAR-NK cells: a promising cellular immunotherapy for cancer","volume":"59","author":"Xie","year":"2020","journal-title":"EBioMedicine"},{"issue":"6","key":"2023102617151662800_qiad027-B28","first-page":"1083","article-title":"First-in-man clinical trial of CAR NK-92 cells: safety test of CD33-CAR NK-92 cells in patients with relapsed and refractory acute myeloid leukemia","volume":"8","author":"Tang","year":"2018","journal-title":"Am J Cancer Res"},{"issue":"1","key":"2023102617151662800_qiad027-B29","doi-asserted-by":"crossref","first-page":"11483","DOI":"10.1038\/srep11483","article-title":"CAR-engineered NK cells targeting wild-type EGFR and EGFRvIII enhance killing of glioblastoma and patient-derived glioblastoma stem cells","volume":"5","author":"Han","year":"2015","journal-title":"Sci Rep"},{"issue":"7","key":"2023102617151662800_qiad027-B30","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1111\/jcmm.12810","article-title":"CD19-CAR Engineered NK-92 cells are sufficient to overcome NK cell resistance in B-cell malignancies","volume":"20","author":"Romanski","year":"2016","journal-title":"J Cell Mol Med"},{"issue":"10","key":"2023102617151662800_qiad027-B31","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1089\/hum.2017.157","article-title":"Optimization of human NK cell manufacturing: fully automated separation, improved ex vivo expansion using IL-21 with autologous feeder cells, and generation of anti-CD123-CAR-expressing effector cells","volume":"28","author":"Kl\u00f6\u00df","year":"2017","journal-title":"Hum Gene Ther"},{"issue":"6","key":"2023102617151662800_qiad027-B32","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1056\/NEJMoa1910607","article-title":"Use of CAR-transduced natural killer cells in CD19-positive lymphoid tumors","volume":"382","author":"Liu","year":"2020","journal-title":"N Engl J Med"},{"issue":"2","key":"2023102617151662800_qiad027-B33","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.stem.2018.06.002","article-title":"Human iPSC-derived natural killer cells engineered with chimeric antigen receptors enhance anti-tumor activity","volume":"23","author":"Li","year":"2018","journal-title":"Cell Stem Cell"},{"issue":"3","key":"2023102617151662800_qiad027-B34","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1182\/blood.V84.3.841.841","article-title":"Generation of human natural killer cells from immature progenitors does not require marrow stromal cells","volume":"84","author":"Silva","year":"1994","journal-title":"Blood"},{"issue":"9","key":"2023102617151662800_qiad027-B35","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1182\/blood.V80.9.2182.2182","article-title":"The generation of human natural killer cells from CD34+\/DR- primitive progenitors in long-term bone marrow culture","volume":"80","author":"Miller","year":"1992","journal-title":"Blood"},{"issue":"7","key":"2023102617151662800_qiad027-B36","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1182\/blood.V87.7.2632.bloodjournal8772632","article-title":"Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells","volume":"87","author":"Mrozek","year":"1996","journal-title":"Blood"},{"issue":"8","key":"2023102617151662800_qiad027-B37","doi-asserted-by":"crossref","first-page":"3052","DOI":"10.1182\/blood-2002-09-2876","article-title":"CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity","volume":"101","author":"Fehniger","year":"2003","journal-title":"Blood"},{"issue":"47","key":"2023102617151662800_qiad027-B38","doi-asserted-by":"crossref","first-page":"16606","DOI":"10.1073\/pnas.0407522101","article-title":"Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs","volume":"101","author":"Ferlazzo","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"2023102617151662800_qiad027-B39","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.immuni.2005.01.013","article-title":"A human CD34(+) subset resides in lymph nodes and differentiates in CD56bright natural killer cells","volume":"22","author":"Freud","year":"2005","journal-title":"Immunity"},{"issue":"1","key":"2023102617151662800_qiad027-B40","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1600-065X.2006.00451.x","article-title":"Human natural killer cell development","volume":"214","author":"Freud","year":"2006","journal-title":"Immunol Rev"},{"issue":"11","key":"2023102617151662800_qiad027-B41","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S1471-4906(01)02060-9","article-title":"The biology of human natural killer-cell subsets","volume":"22","author":"Cooper","year":"2001","journal-title":"Trends Immunol"},{"issue":"3","key":"2023102617151662800_qiad027-B42","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1182\/blood-2007-09-077438","article-title":"Human natural killer cells","volume":"112","author":"Caligiuri","year":"2008","journal-title":"Blood"},{"issue":"10","key":"2023102617151662800_qiad027-B43","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.1182\/blood.V97.10.3146","article-title":"Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset","volume":"97","author":"Cooper","year":"2001","journal-title":"Blood"},{"issue":"12","key":"2023102617151662800_qiad027-B44","doi-asserted-by":"crossref","first-page":"4480","DOI":"10.4049\/jimmunol.136.12.4480","article-title":"The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes","volume":"136","author":"Lanier","year":"1986","journal-title":"J Immunol"},{"issue":"1","key":"2023102617151662800_qiad027-B45","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4049\/jimmunol.179.1.89","article-title":"CD56bright Human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts","volume":"179","author":"Chan","year":"2007","journal-title":"J Immunol"},{"issue":"8","key":"2023102617151662800_qiad027-B46","doi-asserted-by":"crossref","first-page":"4947","DOI":"10.4049\/jimmunol.178.8.4947","article-title":"CD56brightCD16\u2212 Killer Ig-like receptor\u2212 NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation","volume":"178","author":"Romagnani","year":"2007","journal-title":"J Immunol"},{"issue":"1","key":"2023102617151662800_qiad027-B47","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1084\/jem.20082013","article-title":"IL-15 trans-presentation promotes human NK cell development and differentiation in vivo","volume":"206","author":"Huntington","year":"2009","journal-title":"J Exp Med"},{"issue":"1","key":"2023102617151662800_qiad027-B48","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1196\/annals.1392.001","article-title":"Telomere length in human natural killer cell subsets","volume":"1106","author":"Ouyang","year":"2007","journal-title":"Ann N Y Acad Sci"},{"issue":"9","key":"2023102617151662800_qiad027-B49","doi-asserted-by":"crossref","first-page":"3730","DOI":"10.1182\/blood-2002-08-2568","article-title":"Reconstitution of NK cell receptor repertoire following HLA-matched hematopoietic cell transplantation","volume":"101","author":"Shilling","year":"2003","journal-title":"Blood"},{"issue":"4","key":"2023102617151662800_qiad027-B50","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.stem.2014.01.020","article-title":"Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells","volume":"14","author":"Wu","year":"2014","journal-title":"Cell Stem Cell"},{"issue":"7","key":"2023102617151662800_qiad027-B51","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1182\/bloodadvances.2019000699","article-title":"Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing","volume":"4","author":"Smith","year":"2020","journal-title":"Blood Adv"},{"issue":"1","key":"2023102617151662800_qiad027-B52","doi-asserted-by":"crossref","first-page":"3931","DOI":"10.1038\/s41467-019-11947-7","article-title":"Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome","volume":"10","author":"Yang","year":"2019","journal-title":"Nat Commun"},{"issue":"2","key":"2023102617151662800_qiad027-B53","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/nbt.2810","article-title":"Of snowflakes and natural killer cell subsets","volume":"32","author":"Lanier","year":"2014","journal-title":"Nat Biotechnol"},{"issue":"5","key":"2023102617151662800_qiad027-B54","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.immuni.2018.09.009","article-title":"High-dimensional single-cell analysis identifies organ-specific signatures and conserved NK cell subsets in humans and mice","volume":"49","author":"Crinier","year":"2018","journal-title":"Immunity"},{"issue":"5","key":"2023102617151662800_qiad027-B55","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1038\/s41423-020-00574-8","article-title":"Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia","volume":"18","author":"Crinier","year":"2021","journal-title":"Cell Mol Immunol"},{"issue":"5","key":"2023102617151662800_qiad027-B56","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1038\/s41423-021-00653-4","article-title":"Comment to: single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia","volume":"18","author":"Melsen","year":"2021","journal-title":"Cell Mol Immunol"},{"issue":"208","key":"2023102617151662800_qiad027-B57","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3006702","article-title":"Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry","volume":"5","author":"Horowitz","year":"2013","journal-title":"Sci Transl Med"},{"issue":"6","key":"2023102617151662800_qiad027-B58","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.cell.2017.02.021","article-title":"Systemic human ILC precursors provide a substrate for tissue ILC differentiation","volume":"168","author":"Lim","year":"2017","journal-title":"Cell"},{"issue":"7","key":"2023102617151662800_qiad027-B59","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/ni.3481","article-title":"Development of innate lymphoid cells","volume":"17","author":"Zook","year":"2016","journal-title":"Nat Immunol"},{"issue":"4","key":"2023102617151662800_qiad027-B60","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1084\/jem.20052507","article-title":"Evidence for discrete stages of human natural killer cell differentiation in vivo","volume":"203","author":"Freud","year":"2006","journal-title":"J Exp Med"},{"key":"2023102617151662800_qiad027-B61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-60761-362-6_1","article-title":"Purification of human NK cell developmental intermediates from lymph nodes and tonsils","volume":"612","author":"Freud","year":"2010","journal-title":"Methods Mol Biol"},{"issue":"2","key":"2023102617151662800_qiad027-B62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030930","article-title":"Defining early human NK cell developmental stages in primary and secondary lymphoid tissues","volume":"7","author":"Eissens","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"2023102617151662800_qiad027-B63","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.celrep.2016.05.095","article-title":"NKp80 defines a critical step during human natural killer cell development","volume":"16","author":"Freud","year":"2016","journal-title":"Cell Rep"},{"issue":"3","key":"2023102617151662800_qiad027-B64","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.immuni.2018.08.010","article-title":"CD56 expression marks human group 2 innate lymphoid cell divergence from a shared NK cell and group 3 innate lymphoid cell development pathway","volume":"49","author":"Chen","year":"2018","journal-title":"Immunity"},{"issue":"70","key":"2023102617151662800_qiad027-B65","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abi8642","article-title":"Cytotoxic granzyme C-expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity","volume":"7","author":"Nixon","year":"2022","journal-title":"Sci Immunol"},{"issue":"4","key":"2023102617151662800_qiad027-B66","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1002\/eji.202048696","article-title":"Identification of human cytotoxic ILC3s","volume":"51","author":"Krabbendam","year":"2021","journal-title":"Eur J Immunol"},{"issue":"2","key":"2023102617151662800_qiad027-B67","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/nri3365","article-title":"Innate lymphoid cells\u2014a proposal for uniform nomenclature","volume":"13","author":"Spits","year":"2013","journal-title":"Nat Rev Immunol"},{"issue":"5","key":"2023102617151662800_qiad027-B68","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.cell.2018.07.017","article-title":"Innate lymphoid cells: 10 years on","volume":"174","author":"Vivier","year":"2018","journal-title":"Cell"},{"issue":"7","key":"2023102617151662800_qiad027-B69","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1038\/ni.3482","article-title":"NK Cells and type 1 innate lymphoid cells: partners in host defense","volume":"17","author":"Spits","year":"2016","journal-title":"Nat Immunol"},{"issue":"11","key":"2023102617151662800_qiad027-B70","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/ni.2104","article-title":"Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161","volume":"12","author":"Mjosberg","year":"2011","journal-title":"Nat Immunol"},{"issue":"2","key":"2023102617151662800_qiad027-B71","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/ni.3078","article-title":"IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential \u2018inflammatory\u2019 type 2 innate lymphoid cells","volume":"16","author":"Huang","year":"2015","journal-title":"Nat Immunol"},{"issue":"17","key":"2023102617151662800_qiad027-B72","doi-asserted-by":"crossref","first-page":"4008","DOI":"10.1182\/blood-2008-12-192443","article-title":"Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22","volume":"113","author":"Hughes","year":"2009","journal-title":"Blood"},{"issue":"7230","key":"2023102617151662800_qiad027-B73","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/nature07537","article-title":"A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity","volume":"457","author":"Cella","year":"2009","journal-title":"Nature"},{"issue":"1","key":"2023102617151662800_qiad027-B74","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/ni.1668","article-title":"Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells","volume":"10","author":"Cupedo","year":"2009","journal-title":"Nat Immunol"},{"key":"2023102617151662800_qiad027-B75","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/fimmu.2012.00072","article-title":"Functional differences between human NKp44(-) and NKp44(+) RORC(+) innate lymphoid cells","volume":"3","author":"Hoorweg","year":"2012","journal-title":"Front Immunol"},{"issue":"3","key":"2023102617151662800_qiad027-B76","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/imm.12697","article-title":"Functional and phenotypic heterogeneity of group 3 innate lymphoid cells","volume":"150","author":"Melo-Gonzalez","year":"2017","journal-title":"Immunology"},{"issue":"7","key":"2023102617151662800_qiad027-B77","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/ni.3489","article-title":"Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis","volume":"17","author":"Klose","year":"2016","journal-title":"Nat Immunol"},{"issue":"5","key":"2023102617151662800_qiad027-B78","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1182\/blood-2013-11-427781","article-title":"Human innate lymphoid cells","volume":"124","author":"Hazenberg","year":"2014","journal-title":"Blood"},{"issue":"70","key":"2023102617151662800_qiad027-B79","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abj8301","article-title":"CD45RA(+)CD62L(-) ILCs in human tissues represent a quiescent local reservoir for the generation of differentiated ILCs","volume":"7","author":"Kokkinou","year":"2022","journal-title":"Sci Immunol"},{"issue":"6","key":"2023102617151662800_qiad027-B80","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.immuni.2014.11.010","article-title":"Human ROR\u03b3t+ CD34+ cells are lineage-specified progenitors of group 3 ROR\u03b3t+ innate lymphoid cells","volume":"41","author":"Montaldo","year":"2014","journal-title":"Immunity"},{"issue":"5","key":"2023102617151662800_qiad027-B81","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.immuni.2017.10.008","article-title":"The broad spectrum of human natural killer cell diversity","volume":"47","author":"Freud","year":"2017","journal-title":"Immunity"},{"key":"2023102617151662800_qiad027-B82","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2016.00262","article-title":"Human circulating and tissue-resident CD56bright natural killer cell populations","volume":"7","author":"Melsen","year":"2016","journal-title":"Front Immunol"},{"issue":"4","key":"2023102617151662800_qiad027-B83","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.cell.2020.01.022","article-title":"Tissue determinants of human NK cell development, function, and residence","volume":"180","author":"Dogra","year":"2020","journal-title":"Cell"},{"key":"2023102617151662800_qiad027-B84","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.01659","article-title":"Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells","volume":"3","author":"Sojka","year":"2014","journal-title":"Elife"},{"issue":"1","key":"2023102617151662800_qiad027-B85","doi-asserted-by":"crossref","first-page":"3841","DOI":"10.1038\/s41467-019-11632-9","article-title":"Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells","volume":"10","author":"Marquardt","year":"2019","journal-title":"Nat Commun"},{"issue":"10","key":"2023102617151662800_qiad027-B86","doi-asserted-by":"crossref","first-page":"3017","DOI":"10.1002\/eji.201141445","article-title":"The effect of pregnancy on the uterine NK cell KIR repertoire","volume":"41","author":"Male","year":"2011","journal-title":"Eur J Immunol"},{"issue":"8","key":"2023102617151662800_qiad027-B87","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1084\/jem.20030305","article-title":"Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential","volume":"198","author":"Koopman","year":"2003","journal-title":"J Exp Med"},{"issue":"12","key":"2023102617151662800_qiad027-B88","doi-asserted-by":"crossref","first-page":"3824","DOI":"10.1182\/blood-2006-04-020198","article-title":"Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells","volume":"108","author":"Grzywacz","year":"2006","journal-title":"Blood"},{"key":"2023102617151662800_qiad027-B89","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2017.00360","article-title":"Modeling human natural killer cell development in the era of innate lymphoid cells","volume":"8","author":"Scoville","year":"2017","journal-title":"Front Immunol"},{"issue":"5","key":"2023102617151662800_qiad027-B90","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/j.immuni.2016.04.007","article-title":"A progenitor cell expressing transcription factor RORgammat generates all human innate lymphoid cell subsets","volume":"44","author":"Scoville","year":"2016","journal-title":"Immunity"},{"issue":"36","key":"2023102617151662800_qiad027-B91","doi-asserted-by":"crossref","first-page":"14725","DOI":"10.1073\/pnas.1110900108","article-title":"Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection","volume":"108","author":"Lopez-Verg\u00e8s","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"2023102617151662800_qiad027-B92","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1158\/2643-3230.BCD-21-0098","article-title":"Identification and targeting of the developmental blockade in extranodal natural killer\/T-cell lymphoma","volume":"3","author":"Mundy-Bosse","year":"2022","journal-title":"Blood Cancer Discov"},{"issue":"6","key":"2023102617151662800_qiad027-B93","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.immuni.2010.06.007","article-title":"Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue","volume":"32","author":"Hughes","year":"2010","journal-title":"Immunity"},{"issue":"3","key":"2023102617151662800_qiad027-B94","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/ni.2534","article-title":"Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues","volume":"14","author":"Bernink","year":"2013","journal-title":"Nat Immunol"},{"issue":"4","key":"2023102617151662800_qiad027-B95","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.immuni.2013.02.010","article-title":"Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells","volume":"38","author":"Fuchs","year":"2013","journal-title":"Immunity"},{"issue":"1","key":"2023102617151662800_qiad027-B96","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.celrep.2014.05.042","article-title":"The transcription factor AHR prevents the differentiation of a stage 3 innate lymphoid cell subset to natural killer cells","volume":"8","author":"Hughes","year":"2014","journal-title":"Cell Rep"},{"issue":"53","key":"2023102617151662800_qiad027-B97","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aay4218","article-title":"Human innate lymphoid cell precursors express CD48 that modulates ILC differentiation through 2B4 signaling","volume":"5","author":"Tufa","year":"2020","journal-title":"Sci Immunol"},{"issue":"6","key":"2023102617151662800_qiad027-B98","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1002\/eji.201848006","article-title":"Expression of c-kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells","volume":"49","author":"Hochdorfer","year":"2019","journal-title":"Eur J Immunol"},{"issue":"8","key":"2023102617151662800_qiad027-B99","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1084\/jem.20190490","article-title":"KLRG1 And NKp46 discriminate subpopulations of human CD117(+)CRTH2(-) ILCs biased toward ILC2 or ILC3","volume":"216","author":"Nagasawa","year":"2019","journal-title":"J Exp Med"},{"issue":"9","key":"2023102617151662800_qiad027-B100","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1038\/ni.3800","article-title":"Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells","volume":"18","author":"Gao","year":"2017","journal-title":"Nat Immunol"},{"key":"2023102617151662800_qiad027-B101","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.47605","article-title":"Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells","volume":"8","author":"Park","year":"2019","journal-title":"Elife"},{"key":"2023102617151662800_qiad027-B102","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.02180","article-title":"The obese liver environment mediates conversion of NK cells to a less cytotoxic ILC1-like phenotype","volume":"10","author":"Cuff","year":"2019","journal-title":"Front Immunol"},{"issue":"10","key":"2023102617151662800_qiad027-B103","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.it.2019.08.005","article-title":"True detective: unraveling group 1 innate lymphocyte heterogeneity","volume":"40","author":"Riggan","year":"2019","journal-title":"Trends Immunol"},{"issue":"10","key":"2023102617151662800_qiad027-B104","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1016\/j.immuni.2021.07.019","article-title":"An in vitro platform supports generation of human innate lymphoid cells from CD34(+) hematopoietic progenitors that recapitulate ex vivo identity","volume":"54","author":"Hernandez","year":"2021","journal-title":"Immunity"},{"issue":"22","key":"2023102617151662800_qiad027-B105","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1182\/bloodadvances.2018030478","article-title":"CD56 As a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML","volume":"3","author":"Salome","year":"2019","journal-title":"Blood Adv"},{"key":"2023102617151662800_qiad027-B106","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.coi.2020.08.009","article-title":"Natural killers or ILC1s? That is the question","volume":"68","author":"Seillet","year":"2021","journal-title":"Curr Opin Immunol"},{"issue":"9","key":"2023102617151662800_qiad027-B107","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1002\/eji.201848075","article-title":"Suppression of aiolos and ikaros expression by lenalidomide reduces human ILC3-ILC1\/NK cell transdifferentiation","volume":"49","author":"Mazzurana","year":"2019","journal-title":"Eur J Immunol"},{"issue":"1","key":"2023102617151662800_qiad027-B108","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.immuni.2015.06.019","article-title":"Interleukin-12 and -23 control plasticity of CD127(+) group 1 and group 3 innate lymphoid cells in the intestinal lamina propria","volume":"43","author":"Bernink","year":"2015","journal-title":"Immunity"},{"issue":"28","key":"2023102617151662800_qiad027-B109","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2101169118","article-title":"Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment","volume":"118","author":"Moreno-Nieves","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"2023102617151662800_qiad027-B110","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.4049\/jimmunol.1900866","article-title":"TGF-beta and IL-15 synergize through MAPK pathways to drive the conversion of human NK cells to an innate lymphoid cell 1-like phenotype","volume":"204","author":"Hawke","year":"2020","journal-title":"J Immunol"},{"issue":"8","key":"2023102617151662800_qiad027-B111","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.4049\/jimmunol.1202582","article-title":"Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors","volume":"190","author":"Cerdeira","year":"2013","journal-title":"J Immunol"},{"issue":"9","key":"2023102617151662800_qiad027-B112","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/ni.3809","article-title":"SMAD4 Impedes the conversion of NK cells into ILC1-like cells by curtailing non-canonical TGF-beta signaling","volume":"18","author":"Cortez","year":"2017","journal-title":"Nat Immunol"},{"issue":"1","key":"2023102617151662800_qiad027-B113","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/s41467-019-14123-z","article-title":"Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy","volume":"11","author":"Huhn","year":"2020","journal-title":"Nat Commun"},{"issue":"7731","key":"2023102617151662800_qiad027-B114","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/s41586-018-0698-6","article-title":"Single-cell reconstruction of the early maternal-fetal interface in humans","volume":"563","author":"Vento-Tormo","year":"2018","journal-title":"Nature"},{"issue":"8","key":"2023102617151662800_qiad027-B115","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1038\/s41590-019-0425-y","article-title":"Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues","volume":"20","author":"Cella","year":"2019","journal-title":"Nat Immunol"},{"issue":"2","key":"2023102617151662800_qiad027-B116","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.immuni.2015.07.011","article-title":"Identification of a human natural killer cell lineage-restricted progenitor in fetal and adult tissues","volume":"43","author":"Renoux","year":"2015","journal-title":"Immunity"},{"issue":"10","key":"2023102617151662800_qiad027-B117","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.4049\/jimmunol.2000434","article-title":"Notch regulates innate lymphoid cell plasticity during human NK cell development","volume":"205","author":"Nalin","year":"2020","journal-title":"J Immunol"},{"issue":"4","key":"2023102617151662800_qiad027-B118","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/1074-7613(95)90175-2","article-title":"Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset","volume":"3","author":"Galy","year":"1995","journal-title":"Immunity"},{"issue":"1","key":"2023102617151662800_qiad027-B119","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1182\/blood.V93.1.96","article-title":"Single adult human CD34(+)\/Lin-\/CD38(-) progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells","volume":"93","author":"Miller","year":"1999","journal-title":"Blood"},{"issue":"8","key":"2023102617151662800_qiad027-B120","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/S0301-472X(00)00490-2","article-title":"Differential effects of interleukin-3, interleukin-7, interleukin 15, and granulocyte-macrophage colony-stimulating factor in the generation of natural killer and B cells from primitive human fetal liver progenitors","volume":"28","author":"Muench","year":"2000","journal-title":"Exp Hematol"},{"issue":"2","key":"2023102617151662800_qiad027-B121","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.devcel.2006.07.002","article-title":"An unexpected role for IL-3 in the embryonic development of hematopoietic stem cells","volume":"11","author":"Robin","year":"2006","journal-title":"Dev Cell"},{"issue":"7","key":"2023102617151662800_qiad027-B122","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.1182\/blood.V88.7.2458.bloodjournal8872458","article-title":"Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor\/interleukin-3\/interleukin-5 functions","volume":"88","author":"Nishinakamura","year":"1996","journal-title":"Blood"},{"issue":"7","key":"2023102617151662800_qiad027-B123","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1182\/blood-2007-03-082206","article-title":"Notch signaling induces cytoplasmic CD3e expression in human differentiating NK cells","volume":"110","author":"De Smedt","year":"2007","journal-title":"Blood"},{"issue":"7","key":"2023102617151662800_qiad027-B124","doi-asserted-by":"crossref","first-page":"3344","DOI":"10.4049\/jimmunol.1400534","article-title":"Notch signaling at later stages of natural killer cell development enhances KIR expression and functional maturation","volume":"193","author":"Felices","year":"2014","journal-title":"J Immunol"},{"issue":"3","key":"2023102617151662800_qiad027-B125","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1182\/blood.V98.3.705","article-title":"Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2\/L3\/S2","volume":"98","author":"Miller","year":"2001","journal-title":"Blood"},{"key":"2023102617151662800_qiad027-B126","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2017.00755","article-title":"OP9 feeder cells are superior to M2-10B4 cells for the generation of mature and functional natural killer cells from umbilical cord hematopoietic progenitors","volume":"8","author":"Herrera","year":"2017","journal-title":"Front Immunol"},{"issue":"3","key":"2023102617151662800_qiad027-B127","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3109\/15419061.2011.610911","article-title":"Ex vivo differentiation of natural killer cells from human umbilical cord blood CD34+ progenitor cells","volume":"18","author":"Pinho","year":"2011","journal-title":"Cell Commun Adhes"},{"issue":"9","key":"2023102617151662800_qiad027-B128","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.1182\/blood.V83.9.2594.2594","article-title":"Differentiation of natural killer (NK) cells from human primitive marrow progenitors in a stroma-based long-term culture system: identification of a CD34+ 7+ NK progenitor","volume":"83","author":"Miller","year":"1994","journal-title":"Blood"},{"issue":"7","key":"2023102617151662800_qiad027-B129","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1182\/blood.V91.7.2283","article-title":"Natural killer and B-lymphoid potential in CD34+ cells derived from embryonic stem cells differentiated in the presence of vascular endothelial growth factor","volume":"91","author":"Nakayama","year":"1998","journal-title":"Blood"},{"issue":"3","key":"2023102617151662800_qiad027-B130","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/1044-5323(95)90047-0","article-title":"Lymphohematopoietic development from embryonic stem cells in vitro","volume":"7","author":"Nakano","year":"1995","journal-title":"Semin Immunol"},{"issue":"4","key":"2023102617151662800_qiad027-B131","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s12079-018-0448-4","article-title":"Mesenchymal stromal cells of the bone marrow and natural killer cells: cell interactions and cross modulation","volume":"12","author":"Najar","year":"2018","journal-title":"J Cell Commun Signal"},{"issue":"4","key":"2023102617151662800_qiad027-B132","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.bbmt.2011.11.023","article-title":"Natural killer cell differentiation from hematopoietic stem cells: a comparative analysis of heparin- and stromal cell-supported methods","volume":"18","author":"Dezell","year":"2012","journal-title":"Biol Blood Marrow Transplant"},{"issue":"12","key":"2023102617151662800_qiad027-B133","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167555","article-title":"A reproducible method for isolation and in vitro culture of functional human lymphoid stromal cells from tonsils","volume":"11","author":"Bar-Ephraim","year":"2016","journal-title":"PLoS One"},{"issue":"11","key":"2023102617151662800_qiad027-B134","doi-asserted-by":"crossref","first-page":"3317","DOI":"10.1182\/blood.V106.11.3317.3317","article-title":"Murine embryonic liver differentiates human stem cells into a spectrum of NK precursors and polyclonal KIR expressing NK cells","volume":"106","author":"Miller","year":"2005","journal-title":"Blood"},{"issue":"6","key":"2023102617151662800_qiad027-B135","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1634\/stemcells.2004-0120","article-title":"Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures","volume":"23","author":"Oostendorp","year":"2005","journal-title":"Stem Cells"},{"issue":"5175","key":"2023102617151662800_qiad027-B136","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1126\/science.8066449","article-title":"Generation of lymphohematopoietic cells from embryonic stem cells in culture","volume":"265","author":"Nakano","year":"1994","journal-title":"Science"},{"issue":"19","key":"2023102617151662800_qiad027-B137","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1182\/bloodadvances.2018019059","article-title":"NK cell development in a human stem cell niche: KIR expression occurs independently of the presence of HLA class I ligands","volume":"2","author":"Zhao","year":"2018","journal-title":"Blood Adv"},{"issue":"4","key":"2023102617151662800_qiad027-B138","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1182\/blood.V99.4.1183","article-title":"Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity","volume":"99","author":"Oostendorp","year":"2002","journal-title":"Blood"},{"issue":"12","key":"2023102617151662800_qiad027-B139","doi-asserted-by":"crossref","first-page":"4516","DOI":"10.1182\/blood.V91.12.4516","article-title":"Ex vivo culture of CD34+\/Lin\u2212\/DR\u2212 cells in stroma-derived soluble factors, interleukin-3, and macrophage inflammatory protein-1\u03b1 maintains not only myeloid but also lymphoid progenitors in a novel switch culture assay","volume":"91","author":"Miller","year":"1998","journal-title":"Blood"},{"issue":"6","key":"2023102617151662800_qiad027-B140","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1073\/pnas.1016257108","article-title":"CD34 + hematopoietic precursors are present in human decidua and differentiate into natural killer cells upon interaction with stromal cells","volume":"108","author":"Vacca","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"2023102617151662800_qiad027-B141","doi-asserted-by":"crossref","first-page":"3647","DOI":"10.1182\/blood.V92.10.3647","article-title":"Flt3 ligand promotes the generation of a distinct CD34(+) human natural killer cell progenitor that responds to interleukin-15","volume":"92","author":"Yu","year":"1998","journal-title":"Blood"},{"key":"2023102617151662800_qiad027-B142","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01869","article-title":"Natural killer cells: development, maturation, and clinical utilization","volume":"9","author":"Abel","year":"2018","journal-title":"Front Immunol"},{"issue":"5","key":"2023102617151662800_qiad027-B143","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.3324\/haematol.2019.228064","article-title":"A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification","volume":"106","author":"Ackermann","year":"2021","journal-title":"Haematologica"},{"issue":"4","key":"2023102617151662800_qiad027-B144","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1182\/blood.V90.4.1345","article-title":"Stem cell factor and hematopoiesis","volume":"90","author":"Broudy","year":"1997","journal-title":"Blood"},{"issue":"13","key":"2023102617151662800_qiad027-B145","doi-asserted-by":"crossref","first-page":"4121","DOI":"10.1002\/j.1460-2075.1991.tb04989.x","article-title":"Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis","volume":"10","author":"Blume-Jensen","year":"1991","journal-title":"EMBO J"},{"issue":"10","key":"2023102617151662800_qiad027-B146","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202010118","article-title":"Membrane-bound SCF and VCAM-1 synergistically regulate the morphology of hematopoietic stem cells","volume":"220","author":"Hao","year":"2021","journal-title":"J Cell Biol"},{"issue":"7382","key":"2023102617151662800_qiad027-B147","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nature10783","article-title":"Endothelial and perivascular cells maintain haematopoietic stem cells","volume":"481","author":"Ding","year":"2012","journal-title":"Nature"},{"issue":"2","key":"2023102617151662800_qiad027-B148","first-page":"174","article-title":"Sl\/Sld hematopoietic progenitors are deficient in situ","volume":"22","author":"Barker","year":"1994","journal-title":"Exp Hematol"},{"issue":"6","key":"2023102617151662800_qiad027-B149","first-page":"542","article-title":"Early transplantation to a normal microenvironment prevents the development of steel hematopoietic stem cell defects","volume":"25","author":"Barker","year":"1997","journal-title":"Exp Hematol"},{"issue":"12","key":"2023102617151662800_qiad027-B150","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1016\/j.exphem.2003.08.015","article-title":"Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region","volume":"31","author":"Driessen","year":"2003","journal-title":"Exp Hematol."},{"issue":"7","key":"2023102617151662800_qiad027-B151","first-page":"691","article-title":"Natural killing by spleen cells from W\/Wv and Sl\/Sld anemic mice","volume":"9","author":"Seaman","year":"1981","journal-title":"Exp Hematol"},{"issue":"9","key":"2023102617151662800_qiad027-B152","doi-asserted-by":"crossref","first-page":"3647","DOI":"10.1182\/blood.V90.9.3647","article-title":"Stem cell factor enhances interleukin-2\u2013mediated expansion of murine natural killer cells in vivo","volume":"90","author":"Fehniger","year":"1997","journal-title":"Blood"},{"issue":"3","key":"2023102617151662800_qiad027-B153","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.drup.2009.04.001","article-title":"FLT3 inhibition and mechanisms of drug resistance in mutant FLT3-positive AML","volume":"12","author":"Weisberg","year":"2009","journal-title":"Drug Resist Updat"},{"issue":"5","key":"2023102617151662800_qiad027-B154","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1182\/blood-2002-02-0492","article-title":"The roles of FLT3 in hematopoiesis and leukemia","volume":"100","author":"Gilliland","year":"2002","journal-title":"Blood"},{"issue":"11","key":"2023102617151662800_qiad027-B155","doi-asserted-by":"crossref","first-page":"3489","DOI":"10.1182\/blood.V95.11.3489","article-title":"Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells","volume":"95","author":"McKenna","year":"2000","journal-title":"Blood"},{"issue":"4","key":"2023102617151662800_qiad027-B156","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S1074-7613(02)00419-3","article-title":"Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool","volume":"17","author":"Sitnicka","year":"2002","journal-title":"Immunity"},{"issue":"6","key":"2023102617151662800_qiad027-B157","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1182\/blood.V88.6.2004.bloodjournal8862004","article-title":"Hematologic effects of flt3 ligand in vivo in mice","volume":"88","author":"Brasel","year":"1996","journal-title":"Blood"},{"issue":"6","key":"2023102617151662800_qiad027-B158","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.4049\/jimmunol.0900685","article-title":"In vivo role of flt3 ligand and dendritic cells in NK cell homeostasis","volume":"184","author":"Guimond","year":"2010","journal-title":"J Immunol"},{"issue":"7","key":"2023102617151662800_qiad027-B159","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.3390\/cancers13071525","article-title":"The Flt3L\/Flt3 axis in dendritic cell biology and cancer immunotherapy","volume":"13","author":"Cueto","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"2","key":"2023102617151662800_qiad027-B160","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1084\/jem.20030323","article-title":"Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo","volume":"198","author":"Karsunky","year":"2003","journal-title":"J Exp Med"},{"issue":"9","key":"2023102617151662800_qiad027-B161","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1182\/blood.V88.9.3371.bloodjournal8893371","article-title":"Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand","volume":"88","author":"McClanahan","year":"1996","journal-title":"Blood"},{"key":"2023102617151662800_qiad027-B162","first-page":"1012","article-title":"Flt3-ligand production by human bone marrow stromal cells","volume":"10","author":"Lisovsky","year":"1996","journal-title":"Leukemia"},{"issue":"4","key":"2023102617151662800_qiad027-B163","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/CJI.0b013e3181cd872d","article-title":"IL-7 enhances survival of human CD56bright NK cells","volume":"33","author":"Michaud","year":"2010","journal-title":"J Immunother"},{"issue":"4","key":"2023102617151662800_qiad027-B164","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.4049\/jimmunol.1200586","article-title":"Identification of IL-7\u2013producing cells in primary and secondary lymphoid organs using IL-7\u2013GFP knock-in mice","volume":"189","author":"Hara","year":"2012","journal-title":"J Immunol"},{"issue":"11","key":"2023102617151662800_qiad027-B165","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1038\/ni1513","article-title":"Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells","volume":"8","author":"Link","year":"2007","journal-title":"Nat Immunol"},{"key":"2023102617151662800_qiad027-B166","article-title":"Transcription factors associated with IL-15 cytokine signaling during NK cell development","volume":"12","author":"Wang","year":"2021","journal-title":"Front Immunol"},{"issue":"8","key":"2023102617151662800_qiad027-B167","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/ni.2936","article-title":"The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells","volume":"15","author":"Mar\u00e7ais","year":"2014","journal-title":"Nat Immunol"},{"issue":"5","key":"2023102617151662800_qiad027-B168","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/jlb.57.5.763","article-title":"IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2","volume":"57","author":"Giri","year":"1995","journal-title":"J Leukoc Biol"},{"issue":"5","key":"2023102617151662800_qiad027-B169","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S1074-7613(00)80664-0","article-title":"IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation","volume":"9","author":"Lodolce","year":"1998","journal-title":"Immunity"},{"issue":"5","key":"2023102617151662800_qiad027-B170","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1073\/pnas.1318281111","article-title":"Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo","volume":"111","author":"Cui","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"12","key":"2023102617151662800_qiad027-B171","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1038\/ni.3566","article-title":"Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs","volume":"17","author":"Gil-Cruz","year":"2016","journal-title":"Nat Immunol"},{"issue":"15","key":"2023102617151662800_qiad027-B172","doi-asserted-by":"crossref","first-page":"5616","DOI":"10.1073\/pnas.0307442101","article-title":"Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor \u03b1 expression","volume":"101","author":"Schluns","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2023102617151662800_qiad027-B173","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1182\/blood-2011-10-384362","article-title":"Circulating IL-15 exists as heterodimeric complex with soluble IL-15R\u03b1 in human and mouse serum","volume":"120","author":"Bergamaschi","year":"2012","journal-title":"Blood"},{"issue":"24","key":"2023102617151662800_qiad027-B174","doi-asserted-by":"crossref","first-page":"9166","DOI":"10.1073\/pnas.0600240103","article-title":"Converting IL-15 to a superagonist by binding to soluble IL-15R\u03b1","volume":"103","author":"Rubinstein","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2023102617151662800_qiad027-B175","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1073\/pnas.1911678117","article-title":"Trans-endocytosis of intact IL-15R\u03b1\u2013IL-15 complex from presenting cells into NK cells favors signaling for proliferation","volume":"117","author":"Anton","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"9","key":"2023102617151662800_qiad027-B176","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.bbmt.2009.06.002","article-title":"The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34+ cord blood hematopoietic progenitor cells","volume":"15","author":"Beck","year":"2009","journal-title":"Biol Blood Marrow Transplant"},{"issue":"10","key":"2023102617151662800_qiad027-B177","doi-asserted-by":"crossref","first-page":"6168","DOI":"10.4049\/jimmunol.0803036","article-title":"Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15","volume":"182","author":"Haraguchi","year":"2009","journal-title":"J Immunol"},{"issue":"7","key":"2023102617151662800_qiad027-B178","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1084\/jem.194.7.991","article-title":"Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation","volume":"194","author":"Jaleco","year":"2001","journal-title":"J Exp Med"},{"issue":"9","key":"2023102617151662800_qiad027-B179","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.1182\/blood-2004-11-4237","article-title":"Jagged2 promotes the development of natural killer cells and the establishment of functional natural killer cell lines","volume":"105","author":"DeHart","year":"2005","journal-title":"Blood"},{"issue":"1","key":"2023102617151662800_qiad027-B180","doi-asserted-by":"crossref","first-page":"352","DOI":"10.4049\/jimmunol.0803183","article-title":"Notch ligands expressed by follicular dendritic cells protect germinal center B cells from apoptosis","volume":"183","author":"Yoon","year":"2009","journal-title":"J Immunol"},{"issue":"11","key":"2023102617151662800_qiad027-B181","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.3324\/haematol.2019.230854","article-title":"Notch in the niche: new insights into the role of notch signaling in the bone marrow","volume":"104","author":"Vanderbeck","year":"2019","journal-title":"Haematologica"},{"issue":"6","key":"2023102617151662800_qiad027-B182","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/sj.cdd.4400374","article-title":"Expression of the lymphotoxin \u03b2 receptor on follicular stromal cells in human lymphoid tissues","volume":"5","author":"Murphy","year":"1998","journal-title":"Cell Death Differ"},{"issue":"3","key":"2023102617151662800_qiad027-B183","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.4049\/jimmunol.166.3.1684","article-title":"Signal via lymphotoxin-\u03b2R on bone marrow stromal cells is required for an early checkpoint of NK cell development","volume":"166","author":"Wu","year":"2001","journal-title":"J Immunol"},{"issue":"11","key":"2023102617151662800_qiad027-B184","doi-asserted-by":"crossref","first-page":"6336","DOI":"10.1073\/pnas.96.11.6336","article-title":"Requirement for membrane lymphotoxin in natural killer cell development","volume":"96","author":"Iizuka","year":"1999","journal-title":"Proc Natl Acad ScI U S A"},{"key":"2023102617151662800_qiad027-B185","first-page":"13","article-title":"Role of lymphotoxin and homeostatic chemokines in the development and function of local lymphoid tissues in the respiratory tract","volume":"26","author":"Rangel-Moreno","year":"2007","journal-title":"Inmunologia"},{"issue":"25","key":"2023102617151662800_qiad027-B186","doi-asserted-by":"crossref","first-page":"14661","DOI":"10.1074\/jbc.271.25.14661","article-title":"TRAF5, an activator of NF-\u03baB and putative signal transducer for the lymphotoxin-\u03b2 receptor","volume":"271","author":"Nakano","year":"1996","journal-title":"J Biol Chem"},{"issue":"6","key":"2023102617151662800_qiad027-B187","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1002\/eji.201444885","article-title":"Dendritic cell regulation of NK-cell responses involves lymphotoxin-\u03b1, IL-12, and TGF-\u03b2","volume":"45","author":"Sarhan","year":"2015","journal-title":"Eur J Immunol"},{"issue":"5136","key":"2023102617151662800_qiad027-B188","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1126\/science.8235625","article-title":"Immune responses in interleukin-2-deficient mice","volume":"262","author":"K\u00fcndig","year":"1993","journal-title":"Science"},{"issue":"1","key":"2023102617151662800_qiad027-B189","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3390\/biom12010004","article-title":"Role of IL-10-producing natural killer cells in the regulatory mechanisms of inflammation during systemic infection","volume":"12","author":"Martinez-Espinosa","year":"2021","journal-title":"Biomolecules"},{"issue":"4","key":"2023102617151662800_qiad027-B190","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1365-2567.2007.02730.x","article-title":"Interleukin-21 activates human natural killer cells and modulates their surface receptor expression","volume":"123","author":"Skak","year":"2008","journal-title":"Immunology"},{"issue":"12","key":"2023102617151662800_qiad027-B191","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.1002\/eji.200324533","article-title":"IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors","volume":"33","author":"Sivori","year":"2003","journal-title":"Eur J Immunol"},{"issue":"415","key":"2023102617151662800_qiad027-B192","doi-asserted-by":"crossref","first-page":"ra19","DOI":"10.1126\/scisignal.aad1884","article-title":"TGF-beta inhibits the activation and functions of NK cells by repressing the mTOR pathway","volume":"9","author":"Viel","year":"2016","journal-title":"Sci Signal"},{"issue":"9","key":"2023102617151662800_qiad027-B193","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0022842","article-title":"Human tumour immune evasion via TGF-beta blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity","volume":"6","author":"Wilson","year":"2011","journal-title":"PLoS One"},{"issue":"7","key":"2023102617151662800_qiad027-B194","doi-asserted-by":"crossref","first-page":"4120","DOI":"10.1073\/pnas.0730640100","article-title":"Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells","volume":"100","author":"Castriconi","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"2023102617151662800_qiad027-B195","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.immuni.2006.03.016","article-title":"Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells","volume":"24","author":"Yu","year":"2006","journal-title":"Immunity"},{"key":"2023102617151662800_qiad027-B196","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01502","article-title":"Liver-derived TGF-beta maintains the eomes(hi)Tbet(lo) phenotype of liver resident natural killer cells","volume":"10","author":"Harmon","year":"2019","journal-title":"Front Immunol"},{"issue":"3","key":"2023102617151662800_qiad027-B197","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1002\/1521-4141(200103)31:3<792::AID-IMMU792>3.0.CO;2-U","article-title":"Interleukin-1beta costimulates interferon-gamma production by human natural killer cells","volume":"31","author":"Cooper","year":"2001","journal-title":"Eur J Immunol"},{"issue":"25","key":"2023102617151662800_qiad027-B198","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1091\/mbc.e17-08-0508","article-title":"Acquisition of cell migration defines NK cell differentiation from hematopoietic stem cell precursors","volume":"28","author":"Lee","year":"2017","journal-title":"Mol Biol Cell"},{"issue":"4","key":"2023102617151662800_qiad027-B199","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1002\/JLB.1MA0420-635R","article-title":"Generation of cell-derived matrices that support human NK cell migration and differentiation","volume":"108","author":"Lee","year":"2020","journal-title":"J Leukoc Biol"},{"issue":"1","key":"2023102617151662800_qiad027-B200","doi-asserted-by":"crossref","first-page":"12171","DOI":"10.1038\/ncomms12171","article-title":"Human NK cell development requires CD56-mediated motility and formation of the developmental synapse","volume":"7","author":"Mace","year":"2016","journal-title":"Nat Commun"},{"issue":"1","key":"2023102617151662800_qiad027-B201","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1749-6632.2009.04609.x","article-title":"Novel trafficking routes for hematopoietic stem and progenitor cells","volume":"1176","author":"Massberg","year":"2009","journal-title":"Ann N Y Acad Sci"},{"issue":"5","key":"2023102617151662800_qiad027-B202","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s004290100210","article-title":"Morphology and immunology of the human palatine tonsil","volume":"204","author":"Nave","year":"2001","journal-title":"Anat Embryol (Berl)"},{"issue":"2","key":"2023102617151662800_qiad027-B203","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/0196-0709(89)90135-X","article-title":"Functional architecture of the nasopharyngeal tonsil","volume":"10","author":"Fujiyoshi","year":"1989","journal-title":"Am J Otolaryngol"},{"issue":"6","key":"2023102617151662800_qiad027-B204","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/nri3846","article-title":"Lymph node fibroblastic reticular cells in health and disease","volume":"15","author":"Fletcher","year":"2015","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"2023102617151662800_qiad027-B205","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/imr.12748","article-title":"Fibroblastic reticular cells at the nexus of innate and adaptive immune responses","volume":"289","author":"Perez-Shibayama","year":"2019","journal-title":"Immunol Rev"},{"issue":"6","key":"2023102617151662800_qiad027-B206","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.immuni.2006.10.011","article-title":"Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes","volume":"25","author":"Baj\u00e9noff","year":"2006","journal-title":"Immunity"},{"key":"2023102617151662800_qiad027-B207","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/402038","article-title":"Multifunctional roles of reticular fibroblastic cells: more than meets the eye?","volume":"2014","author":"Alvarenga","year":"2014","journal-title":"J Immunol Res"},{"key":"2023102617151662800_qiad027-B208","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.683396","article-title":"In situ characterization of human lymphoid tissue immune cells by multispectral confocal imaging and quantitative image analysis; implications for HIV reservoir characterization","volume":"12","author":"Moysi","year":"2021","journal-title":"Front Immunol"},{"issue":"1","key":"2023102617151662800_qiad027-B209","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1038\/s41467-021-21994-8","article-title":"Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells","volume":"12","author":"Pascual-Reguant","year":"2021","journal-title":"Nat Commun"},{"issue":"3","key":"2023102617151662800_qiad027-B210","doi-asserted-by":"crossref","first-page":"950","DOI":"10.4049\/jimmunol.2100162","article-title":"Differential integrin adhesome expression defines human NK cell residency and developmental stage","volume":"207","author":"Hegewisch-Solloa","year":"2021","journal-title":"J Immunol"},{"key":"2023102617151662800_qiad027-B211","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.647358","article-title":"Natural killer cell integrins and their functions in tissue residency","volume":"12","author":"Shannon","year":"2021","journal-title":"Front Immunol"},{"issue":"8","key":"2023102617151662800_qiad027-B212","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1369\/jhc.4A6253.2004","article-title":"Differential expression of basement membrane components in lymphatic tissues","volume":"52","author":"M\u00e4\u00e4tt\u00e3","year":"2004","journal-title":"J Histochem Cytochem"},{"issue":"3","key":"2023102617151662800_qiad027-B213","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1084\/jem.20051474","article-title":"Natural killer cell behavior in lymph nodes revealed by static and real-time imaging","volume":"203","author":"Bajenoff","year":"2006","journal-title":"J Exp Med"},{"issue":"29","key":"2023102617151662800_qiad027-B214","doi-asserted-by":"crossref","first-page":"12081","DOI":"10.1073\/pnas.0702867104","article-title":"Natural killer cells actively patrol peripheral lymph nodes forming stable conjugates to eliminate MHC-mismatched targets","volume":"104","author":"Garrod","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2023102617151662800_qiad027-B215","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00062752-199901000-00007","article-title":"Integrins and signal transduction","volume":"6","author":"Dedhar","year":"1999","journal-title":"Curr Opin Hematol"},{"issue":"5","key":"2023102617151662800_qiad027-B216","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/jcb.20127","article-title":"Structural and functional characteristics of S1P receptors","volume":"92","author":"Sanchez","year":"2004","journal-title":"J Cell Biochem"},{"issue":"11","key":"2023102617151662800_qiad027-B217","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1084\/jem.20090525","article-title":"T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow","volume":"206","author":"Jenne","year":"2009","journal-title":"J Exp Med"},{"issue":"7","key":"2023102617151662800_qiad027-B218","doi-asserted-by":"crossref","first-page":"E700","DOI":"10.1073\/pnas.1413886112","article-title":"PTEN regulates natural killer cell trafficking in vivo","volume":"112","author":"Leong","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"2023102617151662800_qiad027-B219","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/MOT.0000000000000488","article-title":"Harnessing the lymph node microenvironment","volume":"23","author":"O\u2019Neill","year":"2018","journal-title":"Curr Opin Organ Transplant"},{"issue":"11","key":"2023102617151662800_qiad027-B220","doi-asserted-by":"crossref","first-page":"7833","DOI":"10.4049\/jimmunol.177.11.7833","article-title":"Evidence for NK cell subsets based on chemokine receptor expression","volume":"177","author":"Berahovich","year":"2006","journal-title":"J Immunol"},{"issue":"12","key":"2023102617151662800_qiad027-B221","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1038\/ni1523","article-title":"Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor","volume":"8","author":"Walzer","year":"2007","journal-title":"Nat Immunol"},{"issue":"10","key":"2023102617151662800_qiad027-B222","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1182\/blood-2009-08-237784","article-title":"CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus","volume":"115","author":"Zlotoff","year":"2010","journal-title":"Blood"},{"key":"2023102617151662800_qiad027-B223","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103794","article-title":"Implications of the accumulation of CXCR5(+) NK cells in lymph nodes of HIV-1 infected patients","volume":"75","author":"Guo","year":"2022","journal-title":"EBioMedicine"},{"issue":"8","key":"2023102617151662800_qiad027-B224","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/s41423-019-0244-y","article-title":"CXCR4 And CXCR5 orchestrate dynamic germinal center reactions and may contribute to the pathogenesis of systemic lupus erythematosus","volume":"16","author":"Wu","year":"2019","journal-title":"Cell Mol Immunol"},{"issue":"5","key":"2023102617151662800_qiad027-B225","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1002\/1521-4141(200105)31:5<1544::AID-IMMU1544>3.0.CO;2-I","article-title":"BLC (CXCL13) is expressed by different dendritic cell subsets in vitro and in vivo","volume":"31","author":"Vissers","year":"2001","journal-title":"Eur J Immunol"},{"issue":"5447","key":"2023102617151662800_qiad027-B226","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1126\/science.286.5447.2098","article-title":"Chemokines and cell migration in secondary lymphoid organs","volume":"286","author":"Cyster","year":"1999","journal-title":"Science"},{"issue":"2","key":"2023102617151662800_qiad027-B227","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1182\/blood-2010-04-277897","article-title":"CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice","volume":"117","author":"Noda","year":"2011","journal-title":"Blood"},{"issue":"18","key":"2023102617151662800_qiad027-B228","doi-asserted-by":"crossref","first-page":"4863","DOI":"10.1182\/blood-2011-06-362574","article-title":"Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking","volume":"118","author":"Mayol","year":"2011","journal-title":"Blood"},{"issue":"10","key":"2023102617151662800_qiad027-B229","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1038\/s41422-021-00529-2","article-title":"Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells","volume":"31","author":"Liu","year":"2021","journal-title":"Cell Res"},{"issue":"5","key":"2023102617151662800_qiad027-B230","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1084\/jem.20171934","article-title":"Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine","volume":"215","author":"Li","year":"2018","journal-title":"J Exp Med"},{"key":"2023102617151662800_qiad027-B231","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1044398","article-title":"Single-cell transcriptomics in bone marrow delineates CD56(dim)GranzymeK(+) subset as intermediate stage in NK cell differentiation","volume":"13","author":"Melsen","year":"2022","journal-title":"Front Immunol"},{"issue":"2","key":"2023102617151662800_qiad027-B232","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.stem.2018.11.007","article-title":"Human intestinal allografts contain functional hematopoietic stem and progenitor cells that are maintained by a circulating pool","volume":"24","author":"Fu","year":"2019","journal-title":"Cell Stem Cell"}],"container-title":["Journal of Leukocyte Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jleukbio\/advance-article-pdf\/doi\/10.1093\/jleuko\/qiad027\/49789034\/qiad027.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jleukbio\/article-pdf\/114\/5\/487\/52599413\/qiad027.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jleukbio\/article-pdf\/114\/5\/487\/52599413\/qiad027.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T17:18:01Z","timestamp":1698340681000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jleukbio\/article\/114\/5\/487\/7069611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,4]]},"references-count":232,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,3,4]]},"published-print":{"date-parts":[[2023,10,26]]}},"URL":"https:\/\/doi.org\/10.1093\/jleuko\/qiad027","relation":{},"ISSN":["1938-3673"],"issn-type":[{"value":"1938-3673","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,11]]},"published":{"date-parts":[[2023,3,4]]}}}