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It is often overlooked by people that skin, well-known as a solid physical barrier, is also a strong immunological barrier, considering the abundant presence of immune cells including lymphocytes, granulocytes, dendritic cells, and macrophages. What's more, humoral immune components including cytokines, immunoglobulins, and antimicrobial peptides are also rich in the skin. This review centers on skin inflammation (acute and chronic, infection and aseptic inflammation), wound healing, and skin cancer to elucidate the elaborate network of immune cells in skin diseases.<\/jats:p>","DOI":"10.1093\/jleuko\/qiad107","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T03:35:57Z","timestamp":1695008157000},"page":"852-865","source":"Crossref","is-referenced-by-count":24,"title":["Immune cells in skin inflammation, wound healing, and skin cancer"],"prefix":"10.1093","volume":"115","author":[{"given":"Yuhan","family":"Zhang","sequence":"first","affiliation":[{"name":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College , Jiangwangmiao Street No. 12, Xuanwu, Nanjing 210042 , China"},{"name":"Key Laboratory of Basic and Translational Research on Immune-Mediated Skin Diseases, Chinese Academy of Medical Sciences , Jiangwangmiao Street No. 12, Xuanwu, Nanjing 210042 , China"},{"name":"Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs , Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1504-4896","authenticated-orcid":false,"given":"Qianjin","family":"Lu","sequence":"additional","affiliation":[{"name":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College , Jiangwangmiao Street No. 12, Xuanwu, Nanjing 210042 , China"},{"name":"Key Laboratory of Basic and Translational Research on Immune-Mediated Skin Diseases, Chinese Academy of Medical Sciences , Jiangwangmiao Street No. 12, Xuanwu, Nanjing 210042 , China"},{"name":"Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs , Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,18]]},"reference":[{"issue":"5","key":"2024042918514477000_qiad107-B1","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.stem.2020.01.017","article-title":"C\/EBP\u03b2-dependent epigenetic memory induces trained immunity in hematopoietic stem cells","volume":"26","author":"de Laval","year":"2020","journal-title":"Cell Stem Cell"},{"issue":"1","key":"2024042918514477000_qiad107-B2","first-page":"1","article-title":"Antigen-presenting cell engineering. 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