{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T03:57:42Z","timestamp":1777089462654,"version":"3.51.4"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["409262\/2018-8"],"award-info":[{"award-number":["409262\/2018-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["301641\/2019-6"],"award-info":[{"award-number":["301641\/2019-6"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The bacterial genus Borrelia comprises vector-borne spirochetes that have been classified into three major groups: the relapsing fever group (RFG), the Borrelia burgdorferi Johnson, Schmid, Hyde, Steigerwalt &amp; Brenner sensu lato group (Bbsl), and the reptile-monotreme group (RMG). All three groups have been associated mainly with ticks and wild animals, especially rodents, birds, and reptiles. Here, we searched for Borrelia infection among 99 vampire bats [Desmodus rotundus (\u00c9. Geoffroy)] (Chiroptera: Phyllostomidae) from the Brazilian semiarid region. Through molecular investigation of bat internal organs, haplotypes of a potentially novel Borrelia organism were detected in 5% (5\/99) of the bats. Borrelia DNA was detected in the liver, blood, spleen, kidney and brain, suggesting a systemic infection. Phylogenetic analyses inferred from partial sequences of the borrelial rrs and flaB genes indicated that the vampire bat-associated Borrelia sp. of this study form a monophyletic group with a newly reported Borrelia associated with a Colombia bat, distinct from the three main currently recognized groups of Borrelia spp., Bbsl, RFG, and RMG. These novel bat-associated Borrelia spp. from South America might have arisen through an independent event along the borrelial evolutionary history, since previous molecular reports of Borrelia organisms in bats or bat-associated ticks from Africa, Europe, and North America were all classified in the RFG.<\/jats:p>","DOI":"10.1093\/jme\/tjac160","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T15:51:10Z","timestamp":1666367470000},"page":"213-217","source":"Crossref","is-referenced-by-count":10,"title":["Novel <i>Borrelia<\/i> Genotypes from Brazil Indicate a New Group of <i>Borrelia<\/i> spp. Associated with South American Bats"],"prefix":"10.1093","volume":"60","author":[{"given":"Felipe R","family":"Jorge","sequence":"first","affiliation":[{"name":"Department of Preventive Veterinary Medicine and Animal Health, Faculty of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, Av. Orlando Marques de Paiva, 87, Cidade Universit\u00e1ria, S\u00e3o Paulo , SP, 05508-270 , Brazil"},{"name":"PostGraduate Program in Veterinary Sciences, Faculty of Veterinary, State University of Cear\u00e1 - Av. Dr. Silas Munguba, 1700 - Itaperi , Fortaleza, CE , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebasti\u00e1n","family":"Mu\u00f1oz-Leal","sequence":"additional","affiliation":[{"name":"Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepci\u00f3n, Av. Vicente M\u00e9ndez 595 , casilla 537, Chill\u00e1n, \u00d1uble , Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glauber M B","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine and Animal Health, Faculty of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, Av. Orlando Marques de Paiva, 87, Cidade Universit\u00e1ria, S\u00e3o Paulo , SP, 05508-270 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Carolina A","family":"Serpa","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine and Animal Health, Faculty of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, Av. Orlando Marques de Paiva, 87, Cidade Universit\u00e1ria, S\u00e3o Paulo , SP, 05508-270 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meylling M L","family":"Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"PostGraduate Program in Veterinary Sciences, Faculty of Veterinary, State University of Cear\u00e1 - Av. Dr. Silas Munguba, 1700 - Itaperi , Fortaleza, CE , Brazil"},{"name":"Faculty of Veterinary Medicine, INTA University Center - UNINTA, R. Ant\u00f4nio Rodrigues Magalh\u00e3es, 359 - Dom Expedito , Sobral, CE , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena M B","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"PostGraduate Program in Veterinary Sciences, Faculty of Veterinary, State University of Cear\u00e1 - Av. Dr. Silas Munguba, 1700 - Itaperi , Fortaleza, CE , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco B P","family":"Moura","sequence":"additional","affiliation":[{"name":"Department of Anthropozoonoses, Department of Health of Cear\u00e1, Av. Almirante Barroso , 600 \u2013 Praia de Iracema, Fortaleza, CE , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno M","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, INTA University Center - UNINTA, R. Ant\u00f4nio Rodrigues Magalh\u00e3es, 359 - Dom Expedito , Sobral, CE , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9675-3132","authenticated-orcid":false,"given":"Marcelo B","family":"Labruna","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine and Animal Health, Faculty of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, Av. Orlando Marques de Paiva, 87, Cidade Universit\u00e1ria, S\u00e3o Paulo , SP, 05508-270 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,10,21]]},"reference":[{"key":"2023011214432816000_CIT0001","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1093\/jme\/tjab055","article-title":"The family Borreliaceae (Spirochaetales), a diverse group in two genera of tick-borne spirochetes of mammals, birds, and reptiles","volume":"58","author":"Barbour","year":"2021","journal-title":"J. Med. Entomol"},{"key":"2023011214432816000_CIT0002","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1645\/GE-2840.1","article-title":"Description of a new species of bat-associated argasid tick (Acari: Argasidae) from Brazil","volume":"98","author":"Dantas-Torres","year":"2012","journal-title":"J. Parasitol"},{"key":"2023011214432816000_CIT0003","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.3201\/eid1508.090475","article-title":"Fatal borreliosis in bat caused by relapsing fever spirochete, United Kingdom","volume":"15","author":"Evans","year":"2009","journal-title":"Emerg. Infect. Dis"},{"key":"2023011214432816000_CIT0004","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s13071-022-05289-5","article-title":"Historical overview and update on relapsing fever group Borrelia in Latin America","volume":"15","author":"Faccini-Mart\u00ednez","year":"2022","journal-title":"Parasit. Vectors"},{"key":"2023011214432816000_CIT0005","volume-title":"Perfil Municipal, Fortaleza","author":"(IPECE) Instituto de Pesquisa e Estrat\u00e9gia Econ\u00f4mica do Cear\u00e1.","year":"2017"},{"key":"2023011214432816000_CIT0006","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s10493-022-00709-8","article-title":"New records of soft ticks (Acari: Argasidae) in the Caatinga biome of Brazil, with a phylogenetic analysis of argasids using the nuclear Histone 3 (H3) gene","volume":"86","author":"Jorge","year":"2022","journal-title":"Exp. Appl. Acarol"},{"key":"2023011214432816000_CIT0007","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1093\/nar\/gkf436","article-title":"MAFFT: A novel method for rapid multiple sequence alignment based on fast Fourier transform","volume":"30","author":"Katoh","year":"2002","journal-title":"Nucleic Acids Res. Spec. 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Infect. Dis"},{"key":"2023011214432816000_CIT0014","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1093\/cid\/ciy850","article-title":"Human borreliosis caused by a New World relapsing fever Borrelia-like organism in the Old World","volume":"69","author":"Qiu","year":"2019","journal-title":"Clin. Infect. Dis"},{"key":"2023011214432816000_CIT0015","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/sysbio\/sys029","article-title":"MrBayes 3.2: Efficient Bayesian phylogenetic inference and model choice across a large model space","volume":"61","author":"Ronquist","year":"2012","journal-title":"Syst. Biol"},{"key":"2023011214432816000_CIT0016","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.1128\/JCM.43.8.3851-3859.2005","article-title":"Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida.","volume":"43","author":"Schwan","year":"2005","journal-title":"J. Clin. 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